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316篇 您的检索式:作者名="Rowland P"
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1Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma显示文摘The major type of human liver cancer is hepatocellular carcinoma(HCC), and there are currently many risk factors that contribute to this deadly disease. The majority of HCC occurrences are associated with chronic hepatitis viral infection, and hepatitis B viral(HBV) infection is currently a major health problem in Eastern Asia. Elucidating the genetic mechanisms associated with HBV-induced HCC has been difficult due to the heterogeneity and genetic complexity associated with this disease. A repertoire of animal models has been broadly used to study the pathophysiology and to develop potential treatment regimens for HBVassociated HCC. The use of these animal models has provided valuable genetic information and has been an important contributor to uncovering the factors involved in liver malignant transformation, invasion and metastasis. Recently, transposon-based mouse models are becoming more widely used in liver cancer research to interrogate the genome by forward genetics and also used to validate genes rapidly in a reverse genetic manner. Importantly, these transposon-based rapid reverse genetic mouse models could become crucial in testing potential therapeutic agents before proceeding to clinical trials in human. Therefore, this review will cover the use of transposon-based mouse models toaddress the problems of liver cancer, especially HBVassociated HCC occurrences in Asia.Amy P Chiu Barbara R Tschida Lilian H Lo Branden S Moriarity Dewi K Rowlands David A Largaespada Vincent W Keng 2015World Journal of Gastroenterology2015,21,42:2
2Impact of polymer films thickness and cavity size on polymer flow during embossing: Toward proces design rules for nanoimprint lithography显示文摘ROWLAND H D SUN A C SCHUNK P R 2005Journal of Micromechanics and Microengineering2005,15,:1
31H-MRS at 4 Tesla in minimally treated early schizophrenia 显示文摘Bustillo JR Rowland LM Mullins P 2010Mol Psychiatry2010,15,:1
4Sequence and location of the poly ctract in aphtho-and cardiovirus RNA显示文摘Black D N Stephenson P Rowlands D J 0,,:1
5Biodegradation of aromatic hydrocarbons in crudes oils from the Barrow Sub-basin of Western Australia显示文摘Volkman J K Alexander R Kagi R I Rowland S J Sheppard P N 1984Org Geochem1984,6,62:1
6Researchers' e-journal use and information seeking behavior显示文摘Nicholas D Williams P Rowlands I Jamali H R 2010Journal of Information Science2010,,36:1
7The primary neutralization epitope of porcine respiratory and reproductive syndrome virus strain VR-2332 is located in the middle of the GP5 ectodomain 显示文摘Plagemann P G Rowland R R Faaberg K S 2002Arch Virol2002,147,12:1
8The Attitudes and Behaviours of Illegal Downloaders显示文摘Williams P Nicholas D Rowlands I 2010Aslib Proceedings2010,62,3:1
9Student digital information-seeking behavior in context显示文摘Nicholas D Huntington P Jamali H R Rowlands I Fieldhouse M 2009Journal of Documentation2009,65,1:1
10cDNA - AFLP reveals a striking overlap in race - specific resistance and wound response gene expression profiles 显示文摘Durrant W E Rowland O Piedras P 2000Plant Cell2000,12,:1
11Vege- tation diversity in an interconnected ephemeral ripari- an system of north central Arizona,USA显示文摘Zimmerman J C de Wald L E Rowlands P G 1999Biolog- ical Conservation1999,90,:1
12Neutralizing epitopes of type O foot-and-mouth disease virus: 1 Identification and charaterization of three functionally independent conformational sites 显示文摘Barnett P V Ouldridge E J Rowlands D J 1989J Gen Virol1989,70,:1
13Applications of anion chromatography in terrestrial environmental research 显示文摘WOODS C ROWLAND A P 1997J Chromat A1997,789,:1
14Tissue rupture and bubble formation during radiofrequency catheter ablation : 'Echoes of a Pop' 显示文摘Juneja R O'Callaghan P Rowland E 2001Circulation2001,103,9:1
15Polymer Deformation and Filling Modes during Microembossing显示文摘Rowland H D King W P 2004Journal of Micromechanics and Microengineering2004,14,:1
16Prebiotic effects: metabolic and health benefits显示文摘Roberfroid M Gibson G R Hoyles L McCartney A L Rastall R Rowland I Wolvers D Watztl B Szajewska H Stahl B Guarner F Respondek F Whelan K Coxam V Davieco M Laotoing L Wittrant Y Delzenne N Cani P Neyrinek A Meheust A 2010British Journal of Nutrition2010,104,2:1
17Physicochemical and thermal characterization of wheat straw hemicelluloses and celluloses 显示文摘SUN R C FANG J M ROWLANDS P 1998Journal of Agricultural and Food Chemistry1998,,46:1
18Impact of Polymer Film Thickness and Cavity Size on Polymer Flow during Embossing:toward Process Design Rules for Nanoimprint Lithography显示文摘Rowland H D Sun A C Schunk P R 2005Journal of Micromechanics and Microengineering2005,15,:1
19Analysis of gene expression associated with cold acclimation in blueberry floral buds using expressed sequence tags 显示文摘DHANARAJ A L SLOVIN J P ROWLAND L J 2004Plant Sci2004,166,:1
201H-MRS at 4 tesla in minimally treated early schizophrenia显示文摘Bustillo JR Rowland LM Mullins P 2010Mol Psychiatry2010,15,6:1
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