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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Finite element modeling of the three-dimensional ground deformations due to tunnelling in son cohesive soils: pant Ⅰ -method of analysis显示文摘 | Lee K M Rowe R K | 1990 | Con'' puters and Geotechnics1990，，10： | 2 |
| 3 | Subsidence owing to unnelling (Ⅱ): Evaluztionof a prediction technique显示文摘 | Rowe R K Lo K Y | 1992 | Canadian Geotechnical Journal1992，29，： | 1 |
| 4 | Selected factors influencing GCL hydraulic conductivity显示文摘 | PETROV R J ROWE R K QUIGLEY R M | 1997 | Journal Geotechnical and Geoenvironmental Engineering1997，123，8： | 1 |
| 5 | Analysis of the three-dimensional ground movements,the Thunder Bay Tunnel显示文摘 | Lee K M Rowe R K | 1991 | Canadian Geotechnical Journal1991，，1： | 1 |
| 6 | A Repeated Nested- logit Model of Atlantic Salmon Fishing 显示文摘 | MOREY R ROWE R WATSON M | 1993 | American Journal of Agricultural Economics1993，75，10： | 1 |
| 7 | High-temperature refractory metal-intermetallic composites显示文摘 | BEWLAY B P ROWE R G | 1996 | JOM1996，1996，： | 1 |
| 8 | An evaluation of simplified techniques for estimating three-dimensional undrained ground movements due to tunneling in soft soils显示文摘 | ROWE R K LEE K M | 1992 | Canadian Geotechnical Journal1992，29，： | 1 |
| 9 | Operative intervention in delivery is associated with compromised early mother-infant interaction显示文摘 | Rowe M H J Fisher J R | 2001 | British Journal of Obstetrics and Gynaecology2001，108，10： | 1 |
| 10 | Finite dement modeling of the three di- mensional ground deformations due to tunneling in soft cohesive soil:part I- method of analysis显示文摘 | LEE K M ROWE R K | 1990 | Computers and Geotechnics1990，2，2： | 1 |
| 11 | Back propagation artificial neural networks for the analysis of quality control charts显示文摘 | Velasco T Rowe M R | 1993 | Computers & Industrial Engineertng1993，25，： | 1 |
| 12 | Predicting thermal cracking of pavements fi'om binder properties: Theoretical basis and field validation 显示文摘 | Bouldin M G Dongre R Rowe G M M | 2000 | Proceedings of the Association of Asphalt Paving Technologists2000，69，： | 1 |
| 13 | Subsidence owing to tunnelling Ⅰ: estimating the gap parameter显示文摘 | LEE K M ROWE R K LO K Y | 1992 | Canadian Geotectmical Journal1992，29，6： | 1 |
| 14 | An evaluation of simplified techniques for estimating three-dimensional undrained ground movements due to tunneling in soft soils显示文摘 | Rowe R K Lee K M | 1992 | Canada Geotech J1992，29，3： | 1 |
| 15 | High temperature refractory metal intermetallic composites 显示文摘 | JACKSON M R BEWLAY B P ROWE R G | 1996 | JOM1996，48，： | 1 |
| 16 | Manufacturing Technology 显示文摘 | Alexander J M Brewer R C Rowe G W | 1999 | Tribology Transactions1999，59，2： | 1 |
| 17 | Modelling of thermally induced desiccation of geosynthetic clay liners显示文摘 | Southen J M Rowe R K | 2005 | Geotextiles and Geomembranes2005，23，： | 1 |
| 18 | Extraction and HPLC Analysis of Halofuginone in Chicken Serum显示文摘 | Beier R C Rowe L D Abd El-Aziz Nasr M I | 1994 | J Liquid Chromatogr1994，17，13： | 1 |
| 19 | Analysis of three-dimensional ground movements: the Thunder Bay Tunnel显示文摘 | Lee K M Rowe R K | 1991 | Canadian Geotechnical Journal1991，28，1： | 1 |
| 20 | Facile Synthesis of Carboxylic Linker on Halofuginone:A Method to Derivatize Haptens Containing both Amine and Hydroxy Functionalities显示文摘 | Rowe L D Beier R C Elissalde M H | 1993 | Synthetic Conmunications1993，23，15： | 1 |
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