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624篇 您的检索式：作者名="Rother"

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	题名	作者	年代	出处	被引量
1	Collagen/hyaluronan based hydrogels releasing sulfated hyaluronan improve dermal wound healing in diabetic mice via reducing inflammatory macrophage activity显示文摘Sustained inflammation associated with dysregulated macrophage activation prevents tissue formation and healing of chronic wounds.Control of inflammation and immune cell functions thus represents a promising approach in the development of advanced therapeutic strategies.Here we describe immunomodulatory hyaluronan/collagen(HA-AC/coll)-based hydrogels containing high-sulfated hyaluronan(sHA)as immunoregulatory component for the modulation of inflammatory macrophage activities in disturbed wound healing.Solute sHA downregulates inflammatory activities of bone marrow-derived and tissue-resident macrophages in vitro.This further affects macrophage-mediated pro-inflammatory activation of skin cells as shown in skin ex-vivo cultures.In a mouse model of acute skin inflammation,intradermal injection of sHA downregulates the inflammatory processes in the skin.This is associated with the promotion of an anti-inflammatory gene signature in skin macrophages indicating a shift of their activation profile.For in vivo translation,we designed HA-AC/coll hydrogels allowing delivery of sHA into wounds over a period of at least one week.Their immunoregulatory capacity was analyzed in a translational experimental approach in skin wounds of diabetic db/db mice,an established model for disturbed wound healing.The sHA-releasing hydrogels improved defective tissue repair with reduced inflammation,augmented pro-regenerative macrophage activation,increased vascularization,and accelerated new tissue formation and wound closure.	Sophia Hauck Paula Zager Norbert Halfter Elke Wandel Marta Torregrossa Ainur Kakpenova Sandra Rother Michelle Ordieres Susann Räthel Albrecht Berg Stephanie Möller Matthias Schnabelrauch Jan C.Simon Vera Hintze Sandra Franz	2021	Bioactive Materials2021，6，12：	7
2	'GrabCut'显示文摘	Carsten Rother Vladimir Kolmogorov Andrew Blake	2004	ACM Transactions on Graphics (TOG)2004，，3：	3
3	莱茵河流域防洪规划——发展及其实施(论文摘编)(英文)显示文摘The River Rhine situated in the middle of central Europe is a striking example for the diverging concerns of natural wetland schemes and human uses. The River Rhine basin covers an area of 190 000 km2 and is settled by 50 million people, living in nine different countries. Only in the 19th century the natural moving water courses of the River Rhine were fixed in a singular riverbed allowing the human utilization of the flood prone areas by agriculture, settlement and infrastructure.	KARL-Heinz Rother	2006	长江流域资源与环境2006，15，5：	3
4	Subtype-selective antagonists of lysophosphatidic acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques显示文摘	ROTHER E BRANDL R BAKER D L	2003	Circulation2003，108，6：	2
5	An unusual case of the nonketotic hyperglycemic Syndrome during childhood显示文摘	Rother KI Schwenk WF	1995	Mayo Clin P Rroc1995，70，1：	1
6	Improvement in the symptoms of smooth muscle dystonia during Eculizumab therapy in paroxysmal nocturnal hemoglobinuria显示文摘	Hill A Rother R P Hillmen P	2005	Haematologica2005，90，12：	1
7	Discovery and development of the complement inhibitor ecuJizumab for the treatment of paroxysmal nocturnal hemoglobinuria 显示文摘	Rother RP Rollins SA Mojcik CF	2007	Nature Biotechnology2007，25，11：	1
8	Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria 显示文摘	Rother RP Rollins SA Mojcik CF	2007	Nat Biotechnol2007，25，11：	1
9	Acute stroke evaluated by time-to-peak mapping during initial and early follow-up perfusion CT studies显示文摘	Rother J Jonetz-Mentzel	1999	AJNR1999，20，10：	1
10	P53downregulates expression of the GI/S cell cycle phosphatase CDC25A显示文摘	Rother K Kirschner R Sanger K	2007	Oncogene2007，26，13：	1
11	Blockade of intravascular hemolysis in PNH with the Terminal Complement Inhibitor Eculizumab Unmasks Low-level hemolysis potentially occurring through C3 opsonization显示文摘	Hill A P Rother R M Risitano A	2006	Blood2006，，108：	1
12	Digital transversal slice imaging in dentalmaxillofacial radiology: from pantomography to cone-beam computed tomography 显示文摘	Fuhrmann A Schulze D Rother U	2003	Int J Comput Dent2003，6，2：	1
13	Grabcut-interactive fore- ground extraction using iterated graph cuts显示文摘	Rother C Kolmogorov V Blake A	2004	ACM Transac- tions on Graphics2004，23，3：	1
14	Disturbed T cell signaling and altered Thl7 and regulatory T cell subsets in the pathogenesis of systemic lupus erythematosus显示文摘	ROTHER N VLAG J	2015	Frontiers in Immunology2015，30，11：	1
15	Hemodynamic assessment of acute stroke using dynamic single-slice computed tomographic perfusion imaging显示文摘	Rother J Jonetzel-Mentzel L Fiala A	2000	Arch Neurol2000，57，：	1
16	Microvascular damage following experimental sinus-vein thrombosis in rats显示文摘	Vosko MR Rother J Friedl B	2003	Acta Neuropathol2003，106，5：	1
17	Depthsensing Indentation Measurements with Vickersand Berkovich Indenters显示文摘	ROTHER B STEINER A DIETRICH D A	1998	J Mater Res1998，13，：	1
18	The Effect of Slight Deformation on Droplet Coalescence in Linear Flows显示文摘	Rother M Davis R	2001	Physics of Fluids2001，13，5：	1
19	Subtype-selective an tagon is oflysophosphatidic Acid recep tors inhibit platelet activation triggered by thelipid core of atherosclerotic plaques显示文摘	ROTHER E BRANDL R BAKER D L	2003	Circulation2003，108，3：	1
20	Subtype-selective antagonists of lysophosphatidic Acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques 显示文摘	Rother E Brandl R Baker DL	2003	Circulation2003，108，6：	1

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