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| 1 | Biodegradable magnesium barrier membrane used for guided bone regeneration in dental surgery显示文摘Barrier membranes are commonly used as part of the dental surgical technique guided bone regeneration(GBR)and are often made of resorbable collagen or non-resorbable materials such as PTFE.While collagen membranes do not provide sufficient mechanical protection of the covered bone defect,titanium reinforced membranes and non-resorbable membranes need to be removed in a second surgery.Thus,biodegradable GBR membranes made of pure magnesium might be an alternative.In this study a biodegradable pure magnesium(99.95%)membrane has been proven to have all of the necessary requirements for an optimal regenerative outcome from both a mechanical and biological perspective.After implantation,the magnesium membrane separates the regenerating bone from the overlying,faster proliferating soft tissue.During the initial healing period,the membrane maintained a barrier function and space provision,whilst retaining the positioning of the bone graft material within the defect space.As the magnesium metal corroded,it formed a salty corrosion layer and local gas cavities,both of which extended the functional lifespan of the membrane barrier capabilities.During the resorption of the magnesium metal and magnesium salts,it was observed that the membrane became surrounded and then replaced by new bone.After the membrane had completely resorbed,only healthy tissue remained.The in vivo performance study demonstrated that the magnesium membrane has a comparable healing response and tissue regeneration to that of a resorbable collagen membrane.Overall,the magnesium membrane demonstrated all of the ideal qualities for a barrier membrane used in GBR treatment. | Patrick Rider Zeljka Peric Kacarevic Akiva Elad Drazen Tadic Daniel Rothamel Gerrit Sauer Fabien Bornert Peter Windisch David Botond Hangyasi Balint Molnar Emely Bortel Bernhard Hesse Frank Witte | 2022 | Bioactive Materials2022，7，8： | 7 |
| 2 | Anglo- genesis pattern of native and cross-linked collagen membranes: an immunohistochemical study in the rat显示文摘 | Schwarz F Rothamel D Herren M | 2006 | Clin Oral Implants Res2006，17，4： | 1 |
| 3 | Immunohistochemi- cal characterization of guided bone regeneration at a dehis- cence-type defect using different barrier membranes: an exper- imental study in dogs 显示文摘 | Schwarz F Rothamel D Herten M | 2008 | Clin Oral Implants Res2008，19，4： | 1 |
| 4 | Salivary calculus diagnosis with 3-dimensional cone-beam computed tomography 显示文摘 | Dreiseidler T Ritter L Rothamel D | 2010 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2010，110，1： | 1 |
| 5 | Clinical evalua- tion of an Er: YAG laser for nonsurgical treatment of peri-im-plantitis: a pilot study 显示文摘 | Schwarz F Sculean A Rothamel D | 2005 | Clin Oral Implants Res2005，16，1： | 1 |
| 6 | Surface- and nonsurface- dependent in vitro effects of bone substitutes on cell viability 显示文摘 | Herren M Rothamel D Schwarz F | 2009 | Clin Oral Inwestig2009，13，2： | 1 |
| 7 | Dimensional ridge alterations following socket preservation using a nanocrystalline hydroxyapatite paste, A histomorphometrical stndy in dogs 显示文摘 | Rothamel D Schwarz F Herten M | | Int J Oral Maxillofac Surg 2OOS 37 (S)0，，： | 1 |
| 8 | High frequency of ep- ithelia/ chimerism in liver transplants demonstrated by microdissection and STR-analysis 显示文摘 | Kleeberger W Rothamel T Gltickner S | 2002 | Hepatology2002，35，1： | 1 |
| 9 | Immunohistochemical characterization of guided bone regeneration at a dehiscence-type defect using different barrier membranes: an experimental study in dogs 显示文摘 | Schwarz F Rothamel D Herren M | 2008 | Clin Oral Implants Res2008，19，4： | 1 |
| 10 | Immunohisto- chemical characterization of guided bone regeneration at a dehiscence-type defect using different barrier membranes: an experimental study in dogs 显示文摘 | Schwarz F Rothamel D Herten M | 2008 | Clin Oral Implants Res2008，19，4： | 1 |
| 11 | Accuracy of peri -Implant bone evaluation using Cone -Beam Computed Tomography, digital intraoral radiographs and histology显示文摘 | Ritter L Elger MC Rothamel D | 2014 | Dent Radio2014，43，20： | 1 |
| 12 | Effects of an Er: YAG laser on mitochondrial activity of human osteosarcoma erived osteoblasts in vitro显示文摘 | Schwarz F Rothamel D Herten M | 2004 | Lasers in Medical Science2004，19，1： | 1 |
| 13 | Yertical ridge augmentation using xenogenous bone blocks : A histomorpho- metric study in dogs 显示文摘 | Rothamel D Schwarz F Herren M el al | 2009 | Int J Oral Maxillofac Implants2009，24，2： | 1 |
| 14 | Evaluation of serological screening of cadaveric sera for donor selection for cornea transplantation 显示文摘 | Heim A Wagner D Rothamel T | 1999 | J Med Virol1999，58，3： | 1 |
| 15 | Laser-assisted microdissection and short tandem repeat PCR for the investigation of graft chimerism after solid organ transplantation显示文摘 | KLEEBERGER W ROTHAMEL T GLOCKNER S | 2000 | Pathobiology2000，68，4： | 1 |
| 16 | Immunohistochemical characterization of guided bone regeneration at a dehis- cence-type defect using different barrier membranes: an experi- mental study in dogs 显示文摘 | Schwarz F Rothamel D Herten M | 2008 | Clin Oral Implants Re s2008，19，4： | 1 |
| 17 | Dimensional ridge alterations following socket preservation using a nanocrystal- line hydroxyapatite paste: a histomorphometrical study in dogs显示文摘 | Rothamel D Schwarz F Herten M | 2008 | Int J Oral Maxillo fac Surq2008，37，8： | 1 |
| 18 | Immunohistochemical characterization of guided bone regeneration at a dehiscence-type defect using different barrier membranes:an experimental study in dogs显示文摘 | Schwarz F Rothamel D Herten M | | 0，，04： | 1 |
| 19 | Biodegradation of differently cross-linked collagen membranes: an experimental study in the rat 显示文摘 | Rothamel D Schwarz F Becker J | 2005 | Clinical Oral Implants Research2005，16，3： | 1 |
| 20 | Immunohistochemical characterization of guided bone regeneration at a dehiscencetype defect using different barrier membranes:an experimental study in dogs 显示文摘 | Schwarz F Rothamel D Herren M | 2008 | Clinical Oral Implants Research2008，19，： | 1 |
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