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| 1 | 三相并网逆变器比例谐振控制及其网压前馈问题分析显示文摘静止坐标系下的比例谐振控制因其具有对特定频率响应速度快、不存在耦合项并易实现谐波补偿这三个显著特点得到了广泛的关注,并被应用于多种分布式发电系统当中。本文对静止坐标系下的比例谐振控制进行了说明与分析,同时针对比例谐振控制的特点,提出了一种带有比例系数的正序网压前馈控制方法。该方法通过引入正序网压前馈环节,相比传统的比例谐振控制方法进一步提高了系统的动态响应能力,在逆变器公用接入点(PCC)电压畸变的情况下,正序网压前馈环节降低了网压畸变对并网电流造成的负面影响,并得到了实验的验证。 | 马琳 金新民 唐芬 Pedro Rodriguez 孙凯 | 2012 | 电工技术学报2012，27，8： | 63 |
| 2 | ESCRT-I Component VPS23A Affects ABA Signaling by Recognizing ABA Receptors for Endosomal Degradation显示文摘受体在过去的十年在植物科学成为了很重要的进展之一的 PYR/PYL/RCAR-type abscisic 酸(骆驼毛的织物) 的最近的发现。在哺乳动物,排序的 endosomal 充当一条重要小径到 downregulate 受体的不同类型,而是它在植物荷尔蒙发信号的角色糟糕被理解。这里,我们报导那 ubiquitin 象 E2 一样蛋白质, VPS23A,是 ESCRT-I 的一个关键部件,否定地调整骆驼毛的织物发信号。VPS23A 与 PYR/PYL/RCAR-type 骆驼毛的织物受体和提高的 VPS23A 的混乱有 epistatic 关系在在骆驼毛的织物处理下面表明小径的 ABA 的关键 kinase OST1 的活动。而且, VPS23A 与 PYR1/PYLs 交往,连接 K63 的 diubiquitin,和 PYL4 在 vivo 拥有连接 K63 的 ubiquitinated 修正。进一步的分析表明 VPS23A 影响 PYR1 和 PYL4 的稳定性的 subcellular 本地化。一起拿,我们的结果建议 VPS23A 经由调停液泡的降级影响 PYR1/PYL4,提供两个的先进理解在植物荷尔蒙发信号的骆驼毛的织物受体和 ESCRT 的周转。 | Feifei Yu Lijuan Lou Miaomiao Tian Qingliang Li Yanglin Ding Xiaoqiang Cao Yaorong Wu Borja Belda-Palazon Pedro L. Rodriguez Shuhua Yang Qi Xie | 2016 | Molecular Plant2016，9，12： | 17 |
| 3 | A Direct Link between Abscisic Acid Sensing and the Chromatin-Remodeling ATPase BRAHMA via Core ABA Signaling Pathway ComDonents显示文摘对干旱的最佳的反应为植物幸存是批评的并且将在气候变化期间影响生物多样性和庄稼性能。有丝分裂地可继承的 epigenetic 或动态染色质状态变化在对干旱压力荷尔蒙 abscisic 酸(骆驼毛的织物) 的植物反应被含有。Arabidopsis SWI/SNF 改变染色质的 ATPase 梵天(BRM ) 由在萌芽期间阻止压力反应小径的早熟的激活调制反应到骆驼毛的织物。我们证明核心骆驼毛的织物发信号小径部件身体上与 BRM 交往并且 post-translationally 由 phosphorylation/dephosphorylation 修改 BRM。基因证据建议 SnRK2.2/2.3 kinases 下游的 BRM 行为,和生物化学的研究鉴别在在 SnRK2 的 BRM 的 C 终端区域的 phosphorylation 地点指向 evolutionarily 被保存的地点。最后, phosphomimetic BRM S1760D S1762D 异种显示骆驼毛的织物超敏性。优先的研究证明 BRM 当面在 ABA 小径住在目标 loci 并且刺激的缺席,但是当骆驼毛的织物不在时仅仅是活跃的。我们的数据建议 BRM 的 SnRK2 依赖的 phosphorylation 导致它的抑制,并且 BRM 的调停 PP2CA 的 dephosphorylation 恢复 BRM 的能力镇压骆驼毛的织物反应。这些调查结果点到存在一快速基于 phosphorylation 换到控制 BRM 活动;这个性质能潜在地被利用在植物改进干旱忍耐。 | Marta Peirats-Llobet Soon-Ki Han Miguel Gonzalez-Guzman Cheol Woong Jeong Lesia Rodriguez Borja Belda-Palazon Doris Wagner Pedro L. Rodriguez | 2016 | Molecular Plant2016，9，1： | 13 |
| 4 | Low platelet count: Predictor of death and graft loss after liver transplantation显示文摘BACKGROUND The impact of platelets on liver transplantation(LT) is well recognized, but not completely understood. Platelets exert dichotomous effects on the graft and on the patient. On the one hand, they are essential for primary hemostasis and tissue repair and regeneration. On the other hand, they support ischemia/reperfusion injury and inflammatory processes. Recent evidence has shown a new role for platelet count(PC) in predicting outcomes after LT.AIM To evaluate if low PC is a predictor of short-and long-term outcomes after LT.METHODS Four hundred and eighty consecutive LT patients were retrospectively assessed.PC from the preoperative to the seventh postoperative day(POD) were considered. C-statistic analysis defined the ideal cutoff point for PC. Cox regression was performed to check whether low PC was a predictor of death,retransplantation or primary changes in graft function within one year after LT.RESULTS The highest median PC was 86 × 109/L [interquartile range(IQR) = 65–100 ×109/L] on seventh POD, and the lowest was 51 × 109/L(IQR = 38–71 × 109/L) on third POD. The C-statistic defined a PC < 70 × 109/L on fifth POD as the ideal cutoff point for predicting death and retransplantation. In the multivariate analysis, platelets < 70 × 109/L on 5 POD was an independent risk factor for death at 12 mo after LT [hazard ratio(HR) = 2.01; 95% confidence interval(CI) 1.06-3.79;P = 0.031]. In the Cox regression, patients with PC < 70 × 109/L on 5 POD had worse graft survival rates up to one year after LT(HR = 2.76; 95%CI 1.52-4.99; P =0.001).CONCLUSION PC < 70 × 109/L on 5 POD is an independent predictor of death in the first year after LT. These results are in agreement with other studies that indicate that low PC after LT is associated with negative outcomes. | Pedro Beltrame Santiago Rodriguez Ajacio Bandeira de Mello Brand?o | 2019 | World Journal of Hepatology2019，11，1： | 2 |
| 5 | Benchmarking of two three-dimensional numerical models in time/space domain to predict railway-induced ground vibrations显示文摘In the last 30 years,the scientific community has developed and proposed different models and numerical approaches for the study of vibrations induced by railway traffic.Most of them are formulated in the frequency/wave number domain and with a 2.5D approach.Three-dimensional numerical models formulated in the time/space domain are less frequently used,mainly due to their high computational cost.Notwithstanding,these models present very attractive characteristics,such as the possibility of considering nonlinear behaviors or the modelling of excess pore pressure and non-homogeneous and non-periodic geometries in the longitudinal direction of the track.In this study,two 3D numerical approaches formulated in the time/space domain are compared and experimentally validated.The first one consists of a finite element approach and the second one of a finite difference approach.The experimental validation in an actual case situated in Carregado(Portugal)shows an acceptable fitting between the numerical results and the actual measurements for both models.However,there are some differences among them.This study therefore includes some recommendations for their use in practical soil dynamics and geotechnical engineering. | Jesus Fernandez-Ruiz Luis E.Medina Rodriguez Pedro Alves Costa Margarita Martinez-Diaz | 2021 | Earthquake Engineering and Engineering Vibration2021，20，1： | 2 |
| 6 | Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction显示文摘In vivo genome editing represents a powerful strategy for both understanding basic biology and treating inherited diseases.However,it remains a challenge to develop universal and efficient in vivo genome-editing tools for tissues that comprise diverse cell types in either a dividing or non-dividing state.Here,we describe a versatile in vivo gene knock-in methodology that enables the targeting of a broad range of mutations and cell types through the insertion of a minigene at an intron of the target gene locus using an intracellularly linearized single homology arm donor.As a proof-of-concept,we focused on a mouse model of prematureaging caused by a dominant point mutation,which is difficult to repair using existing in vivo genome-editing tools.Systemic treatment using our new method ameliorated aging-associated phenotypes and extended animal lifespan,thus highlighting the potential of this methodology for a broad range of in vivo genome-editing applications. | Keiichiro Suzuki Mako Yamamoto Reyna Hernandez-Benitez Zhe Li Christopher Wei Rupa Devi Soligalla Emi Aizawa Fumiyuki Hatanaka Masakazu Kurita Pradeep Reddy Alejandro Ocampo Tomoaki Hishida Masahiro Sakurai Amy NNemeth Estrella Nunez Delicado Josep MCampistol Pierre Magistretti Pedro Guillen Concepcion Rodriguez Esteban Jianhui Gong Yilin Yuan Ying Gu Guang-Hui Liu Carlos Lopez-Otin Jun Wu Kun Zhang Juan Carlos Izpisua Belmonte | 2019 | Cell Research2019，29，10： | 2 |
| 7 | αKLOTHO and sTGFβR2 treatment counteract the osteoarthritic phenotype developed in a rat model显示文摘Dear Editor,Homeostasis and repair are critical biological processes that allow for tissue and organ preservation and function in multicellular organisms.Their regulation and extension vary drastically across the animal kingdom,and mammals show limited tissue-specific regenerative capacity that declines with age.During aging,articular cartilage is one of the tissues that undergo substantial changes in the matrix structure,molecular composition,metabolic activity,and mechanical properties(Loeser et al.2016). | Paloma Martinez-Redondo Isabel Guillen-Guillen Noah Davidsohn Chao Wang Javier Prieto Masakazu Kurita Fumiyuki Hatanaka Cuiqing Zhong Reyna Hernandez-Benitez Tomoaki Hishida Takashi Lezaki Akihisa Sakamoto Amy NNemeth Yuriko Hishida Concepcion Rodriguez Esteban Kensaku Shojima Ling Huang Maxim Shokhirev Estrella Nunez-Delicado Josep MCampistol Isabel Guillen-Vicente Elena Rodriguez-Inigo Juan Manuel Lopez-Alcorocho Marta Guillen-Vicente George Church Pradeep Reddy Pedro Guillen-Garcia Guang-Hui Liu Juan Carlos Izpisua Belmonte | 2020 | Protein & Cell2020，11，3： | 2 |
| 8 | Massive hemorrhage in hemangioblastomas Literature review显示文摘 | de San Pedro JR Rodriguez FA Niguez BF | 2010 | Neurosurg Rev2010，33，1： | 1 |
| 9 | Spatial and temporal variation in marine bacterioplankton diversity as shown by RFLP finger-printing of PCR amplified 16S rDNA 显示文摘 | Acinas S Rodriguez V F Pedros A | 1997 | FEMS Microbiol Ecol1997，24，1： | 1 |
| 10 | Antegrade nailing for fractures of the distal femur显示文摘 | DOMINGUEZ I MORO RODRIGUEZ E De PEDRO MORO JA | 1998 | Clin Orthop1998，，350： | 1 |
| 11 | A new high-efficiency single-phase transformerless PV inverter topo-logy 显示文摘 | Tamas Kerekes Remus Teodorescu Pedro Rodriguez | 2011 | IEEE Transactions on Industrial Electronic s2011，58，1： | 1 |
| 12 | Massive hemorrhage in hemangioblastomas Literature review 显示文摘 | de San Pedro JR Rodriguez FA Niguez BF | 2010 | Neurosurg Rev2010，33，： | 1 |
| 13 | Ascorbate, green tea and grape seed extracts increase the shelf life of low sulphite beef patties 显示文摘 | Sancho Banon Pedro Diaz Mariano Rodriguez | 2007 | Meat Science2007，5，15： | 1 |
| 14 | Decoupled Doub-le Synchronous Reference Frame PLL for Power Converters Control 显示文摘 | Pedro Rodriguez Josep Pou Joan Beragas | 2007 | IEEE Transactions on power electronics2007，22，2： | 1 |
| 15 | Decoupled double synchronous reference frame PLL for power con- verters control显示文摘 | Rodriguez Pedro Pou Josep Bergas Joan | 2007 | IEEE Transactions on Power Electronics2007，22，2： | 1 |
| 16 | Spatial and temporal variation in marine bacterial plankton diversity as shown by RFLP fingerprinting of PCR amplified 16SrDNA显示文摘 | Acinas S G Rodriguez Valera F Pedros Alio C | 1997 | FEMS Microbiological Ecology1997，24，1： | 1 |
| 17 | Reduction of switching losses in active power filters with a new generalized discontinuous-PWM strategy 显示文摘 | Lucian Asiminoaei Pedro Rodriguez Frede Blaabjerg | 2008 | IEEE Transac- tions on Industrial Electronics2008，，： | 1 |
| 18 | Grid-Filter Design for a Multi-megawatt Medium-voltage Voltage-Source Inverter显示文摘 | A A Rockhill Marco Liserre Remus Teoclorescu Pedro Rodriguez | | 0，，04： | 1 |
| 19 | Flexible Active Power Control of Distributed Power Generation Systems During Grid Faults显示文摘 | Pedro Rodriguez Adrian V Timbus Remus Teodorescu | 2009 | IEEE Trans- action on Industrial Electronics2009，54，5： | 1 |
| 20 | Rotor voltage dynamics in the doubly-fed induction generator during grid faults显示文摘 | Francisco K A Lima Alvaro Luna Pedro Rodriguez | 2010 | IEEE Transactions on Power Electronics2010，25，1： | 1 |
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