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| 1 | Inflammatory bowel disease: A descriptive study of 716 local Chilean patients显示文摘AIM: To demographically and clinically characterize inflammatory bowel disease(IBD) from the local registry and update data previously published by our group.METHODS: A descriptive study of a cohort based on a registry of patients aged 15 years or older who were diagnosed with IBD and attended the IBD program at Clínica Las Condes in Santiago, Chile. The registry was created in April 2012 and includes patients registered up to October 2015. The information was anonymously downloaded in a monthly report, and the information on patients with more than one visit was updated. The registry includes demographic, clinical and disease characteristics, including the Montreal Classification, medical treatment, surgeries and hospitalizations for crisis. Data regarding infection with Clostridium difficile(C. difficile) were incorporated in the registry in 2014. Data for patients who received consultations as second opinions and continued treatment at this institution were also analyzed. RESULTS: The study included 716 patients with IBD: 508 patients(71%) were diagnosed with ulcerative colitis(UC), 196 patients(27%) were diagnosed with Crohn's disease(CD) and 12 patients(2%) were diagnosed with unclassifiable IBD. The UC/CD ratio was 2.6/1. The median age was 36 years(range 16-88), and 58% of the patients were female, with a median age at diagnosis of 29 years(range 5-76). In the past 15 years, a sustained increase in the number of patients diagnosed with IBD was observed, where 87% of the patients were diagnosed between the years 2001 and 2015. In the cohort examined in the present study, extensive colitis(50%) and colonic involvement(44%) predominated in the patients with UC and CD, respectively. In CD patients, nonstricturing/non-penetrating behavior was more frequent(80%), and perianal disease was observed in 28% of the patients. There were significant differences in treatment between UC and CD, with a higher use of corticosteroids, and immunosuppressive and biological therapies was observed in the patients with CD(P < 0.05 and P < 0.01). Significant surgical differences were also observed: 5% of the UC patients underwent surgery, whereas 38% of the CD patients required at least one surgery(P < 0.01). The patients with CD were hospitalized more often during their disease course than the patients with UC(55% and 35% of the patients, respectively; P < 0.01). C. difficile infection was acquired by 5% of the patients in each group at some point during the disease course. Nearly half of the patients consulted at the institution for a second opinion, and 32% of these individuals continued treatment at the institution. CONCLUSION: IBD has continued to increase in the study cohort, slowly approaching the level reported in developed countries. | Daniela Simian Daniela Fluxá Lilian Flores Jaime Lubascher Patricio Ibánez Carolina Figueroa Udo Kronberg Raúl Acuna Mauricio Moreno Rodrigo Quera | 2016 | World Journal of Gastroenterology2016，22，22： | 2 |
| 2 | Oil Dispersion of Alumina for Tape Casting显示文摘 | Rodrigo Moreno Gonzalo Cordoba | 1995 | American Ceramic Society Bulletin1995，74，7： | 1 |
| 3 | Synthesis of γ-Al203 anopowders by freeze-drying显示文摘 | Carolina Tallon Rodrigo Moreno M Isabel Nieto | 2006 | Materials Research Bulletin2006，41，： | 1 |
| 4 | Channel plasmon-polaritons:modal shape,dispersion,and losses显示文摘 | Moreno E Garcia-Vidal F J Rodrigo S G | | 0，，23： | 1 |
| 5 | Guiding and focusing of electromagnetic fields with wedge plasmon polaritons显示文摘 | Moreno E Rodrigo S G Bozhevolnyi S I | | 0，，02： | 1 |
| 6 | Direct synthesis of A2(Ti1-yZry)2O7(A=Gd3+,Y3+) solid solutions by ball milling constituent oxides显示文摘 | MORENO K J RODRIGO R S FUENTES A F | 2005 | J Alloys Compounds2005，390，12： | 1 |
| 7 | Guiding and focusing of electromagnetic fields with wedge plasmon polaritons 显示文摘 | MORENO E RODRIGO S G BOZHEVOLNYI S I | 2008 | Physical Review Letters2008，100，02： | 1 |
| 8 | Guiding and Focusing of Electromagnetic Fields with Wedge Plasmon Polaritons 显示文摘 | Moreno E Rodrigo S G Bozhevolnyi S I | 2008 | Phys Rev Lett2008，100，02： | 1 |
| 9 | Influence of Slip Preparation and Casting Conditions on Aqueous Tape Casting of Al2O3显示文摘 | Carlos A Gutie Rrez Rodrigo Moreno | 2001 | Materials Research Bulletin2001，36，： | 1 |
| 10 | White coat effect is not associated with additional increase of target organ damage in true resistant hypertension显示文摘 | Valéria Nasser Figueiredo Luiz Cláudio Martins Leandro Boer-Martins Ana Paula Cabral de Faria Carolina de Haro Moraes Rodrigo Cardoso Santos Armando R. Nogueira Heitor Moreno | 2012 | Medicina Clinica2012，，： | 1 |
| 11 | Direct Synthesis of A22O7 (A=Gd3+,Y3+) Solid Solutions by Ball Milling Constituent Oxides显示文摘 | Karla J Moreno Silva Rodrigo R Antonio F Fuentes | 2005 | Journal of Alloys and Compounds2005，390，： | 1 |
| 12 | Expression,tissue distribution and subcellular localization ofdehydrin TAS14 in salt-stressed tomato plants显示文摘 | Godoy J Lunar R Torres-Schumarm S Moreno J Rodrigo R M Pintor-Toro J A | | 0，，： | 1 |
| 13 | Channel plasmon-polaritons : modal shape, dispersion, and losses显示文摘 | Moreno E Garacial-Vidal F J Rodrigo S G | 2006 | Opt Lett2006，31，： | 1 |
| 14 | Effect of mullite additions on the fracture mode of alumin显示文摘 | Burgos Montes Rodrigo Moreno Carmen Baud in | 2010 | Journal of the European Ceramics Society2010，30，： | 1 |
| 15 | Channel plasmon-polaritons : modal shape, dispersion, and losses 显示文摘 | Moreno E Garcia-Vidal F J Rodrigo S G | 2006 | Optics Letters2006，31，23： | 1 |
| 16 | Effect of mullite additions on the fracture mode of alumin显示文摘 | Burgos Montes Rodrigo Moreno Carmen Baud i n | 2010 | Journal of the European Ceramics Society2010，30，： | 1 |
| 17 | Influence of slip preparation and casting conditions on aqueous tape casting of Al2O3 materials显示文摘 | CARLOS A GUTIERREZ RODRIGO MORENO | 2001 | Research Bulletin2001，36，： | 1 |
| 18 | Influence of Skeletal Site of Origin and Donor Age on Osteoblastic Cell Growth and Differentiation显示文摘 | M. E. Martínez M. T. del Campo S. Medina M. Sánchez M. J. Sánchez-Cabezudo P. Esbrit P. Martínez I. Moreno A. Rodrigo M. V. Garcés L. Munuera | 1999 | Calcified Tissue International1999，，4： | 1 |
| 19 | Colloidal behaviour of mullite powders produced by combustion synthesis 显示文摘 | BURGOS-MONTES Olga MORENO Rodrigo | 2007 | J Eur Ceram Soc2007，27，16： | 1 |
| 20 | Channel plasmon polaritons : modal shape, dispersion, and losses显示文摘 | Moreno E Garcia Vidal F J Rodrigo S G | 2006 | Opt Lett2006，31，： | 1 |
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