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| 1 | Dietary modulation of endogenous host defense peptide synthesis as an alternative approach to in-feed antibiotics显示文摘Traditionally, antibiotics are included in animal feed at subtherapeutic levels for growth promotion and disease prevention.However, recent links between in-feed antibiotics and a rise in antibiotic-resistant pathogens have led to a ban of all antibiotics in livestock production by the European Union in January 2006 and a removal of medically important antibiotics in animal feeds in the United States in January 2017.An urgent need arises for antibiotic alternatives capable of maintaining animal health and productivity without triggering antimicrobial resistance.Host defense peptides(HDP) are a critical component of the animal innate immune system with direct antimicrobial and immunomodulatory activities.While in-feed supplementation of recombinant or synthetic HDP appears to be effective in maintaining animal performance and alleviating clinical symptoms in the context of disease, dietary modulation of the synthesis of endogenous host defense peptides has emerged as a cost-effective,antibiotic-alternative approach to disease control and prevention.Several different classes of smallmolecule compounds have been found capable of promoting HDP synthesis.Among the most efficacious compounds are butyrate and vitamin D.Moreover, butyrate and vitamin D synergize with each other in enhancing HDP synthesis.This review will focus on the regulation of HDP synthesis by butyrate and vitamin D in humans, chickens, pigs, and cattle and argue for potential application of HDP-inducing compounds in antibiotic-free livestock production. | Kelsy Robinson Xi Ma Yulan Liu Shiyan Qiao Yongqing Hou Guolong Zhang | 2018 | Animal Nutrition2018,,2: | 9 |
| 2 | CMOS micromachined low power microlamp vacuum sensor显示文摘 | MA Y ROBINSON A M LAWSON R P W | 2002 | IEEE2002,,: | 2 |
| 3 | Components of complex interventions for healthcare: A narrative synthesis of qualitative studies显示文摘Objective:Qualitative research on therapeutic components is necessary to evaluate the efficacy of complex interventions in healthcare.As few qualitative syntheses have been conducted,this study aimed to derive a new conceptual framework for understanding the components of complex interventions and provide evidence for the implementation and evaluation of complex healthcare interventions.Methods:A systematic search of seven databases was conducted to identify qualitative studies that explored components of complex healthcare interventions.Meta-ethnography was used to analyze the data and thematic analysis was used to build the conceptual framework.Results:Of the 35 included studies,most complex interventions were non-pharmacological,with cancer accounting for 22%,mental health for 14%,and stroke for 8%.Half of the studies were conducted in the United Kingdom.Three main categories emerged:what should healthcare workers do?what qualifications should they have?and what should patients do?Five main themes were identified:psychological,biological,cognitive and behavioral,environmental,and social support.Conclusion:This analysis provides a reference for designing components of complex interventions in further studies. | Sisi Ma He Yu Ning Liang Sijia Zhu Xun Li Nicola Robinson Jianping Liu | 2020 | Journal of Traditional Chinese Medical Sciences2020,7,2: | 2 |
| 4 | Arterial baroreceptor-cardiac reflex sensitivity in the elderly显示文摘 | James MA Robinson TG Panerai RB | | 0,,: | 1 |
| 5 | mTHPC-mediated photodynamic therapy in patients with advanced,incurable head and neck cancer:a multicenter study of 128 patients显示文摘 | D'Cruz AK Robinson MH Biel MA | 2004 | Head Neck2004,26,: | 1 |
| 6 | Treatment of anterior fracture- dislocations of the proximal humerus by open reduction and internal fixation 显示文摘 | Robinson CM Khan LA Akhtar MA | 2006 | J Bone Joint Surg Br2006,4,: | 1 |
| 7 | Treatment of anterior fracture - dislocations of the proximal humerus by open reduction and inter- nal fixation显示文摘 | Robinson CM Khan LAK Akhtar MA | 2006 | J Bone Joint Surg Br2006,4,: | 1 |
| 8 | ChREBP · Mlx is the principal mediator of glucose-induced gene expression in the liver显示文摘 | Ma L Robinson L N Towle H C | 2006 | J Biol Chem2006,281,28: | 1 |
| 9 | An analysis of causes of apical root resorption in patients not treated orthodontically 显示文摘 | Harris EF Robinson QC Woods MA | 1993 | Quintessence Int1993,24,6: | 1 |
| 10 | Restriction of the CD4 T-cell receptor repertoire prevents immune pathology inTGF-betal knockout mice显示文摘 | Robinson RT French MA Kitzmiller TJ | 2006 | Lab Invest2006,86,8: | 1 |
| 11 | Ethnic variation in cardiovascular disease risk factors among children and young adults: findings from the Third National Health and Nutrition Examination Survey, 1988 - 1994 显示文摘 | Winkleby MA Robinson IN Sundquist J | 1999 | JAMAM1999,281,: | 1 |
| 12 | CWR22: androgen--dependent xenograft model derived from a primary human prostatic carcinoma显示文摘 | Wainstein MA He F Robinson D | 1994 | Cancer Res1994,54,23: | 1 |
| 13 | Arterial baroreceptor-eardiac reflex sensitivity in the elderly显示文摘 | James MA Robinson TG Panerai RB | 1996 | Hypertension1996,28,6: | 1 |
| 14 | ChREBP * Mlx is the principal mediator of glucose-induced gene expres- sion in the liver显示文摘 | Ma L Robinson LN Towle HC | 2006 | J Biol Chem2006,281,28: | 1 |
| 15 | Comprehensive geriatric assessment for older adults admitted to hospital: meta-analysis of randomised controlled trials 显示文摘 | Ellis G Whitehead MA Robinson D | 2011 | BMJ2011,343,8878: | 1 |
| 16 | Isomers of conjugated linoleic acid(CLA)are incorporated into egg yolk lipids by CLA-fed laying hens显示文摘 | Jones S Ma D W Robinson F E | 2000 | The Journal of Nutrition2000,130,8: | 1 |
| 17 | ChREBP * Mix is the principal mediator of glucose-induced gene expression in the liver 显示文摘 | Ma L Robinson LN Towle HC | 2006 | J Biol Chem2006,281,28: | 1 |
| 18 | mTHPC-mediated photodynamic therapy in patients with advanced, incurable head and neck cancer: a multicenter study of 128 patients显示文摘 | D' Cruz AK Robinson MH Biel MA | 2004 | Head Neck2004,26,: | 1 |
| 19 | Characterization of a conserve d he lper-T-cellepitope from group A streptococcal M proteins显示文摘 | Robinson JH Case MC Kehoe MA | 1993 | Infect Immun ity1993,61,: | 1 |
| 20 | Arterial baroreceptor cardiac reflex sensitivity in the eldedy显示文摘 | Jamse MA Robinson TG Panerai RB | 1996 | Hypertension1996,28,6: | 1 |