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| 1 | Liver surgery in cirrhosis and portal hypertension显示文摘The prevalence of hepatic cirrhosis in Europe and the United States, currently 250 patients per 100000 inhabitants, is steadily increasing. Thus, we observe a significant increase in patients with cirrhosis and portal hypertension needing liver resections for primary ormetastatic lesions. However, extended liver resections in patients with underlying hepatic cirrhosis and portal hypertension still represent a medical challenge in regard to perioperative morbidity, surgical management and postoperative outcome. The Barcelona Clinic Liver Cancer classification recommends to restrict curative liver resections for hepatocellular carcinoma in cirrhotic patients to early tumor stages in patients with Child A cirrhosis not showing portal hypertension. However, during the last two decades, relevant improvements in preoperative diagnostic, perioperative hepatologic and intensive care management as well as in surgical techniques during hepatic resections have rendered even extended liver resections in higher-degree cirrhotic patients with portal hypertension possible. However, there are few standard indications for hepatic resections in cirrhotic patients and risk stratifications have to be performed in an interdisciplinary setting for each individual patient. We here review the indications, the preoperative risk-stratifications, the morbidity and the mortality of extended resections for primary and metastatic lesions in cirrhotic livers. Furthermore, we provide a review of literature on perioperative management in cirrhotic patients needing extrahepatic abdominal surgery and an overview of surgical options in the treatment of hepatic cirrhosis. | Christina Hackl Hans J Schlitt Philipp Renner Sven A Lang | 2016 | World Journal of Gastroenterology2016，22，9： | 21 |
| 2 | Implication of the intestinal microbiome in complications of cirrhosis显示文摘The intestinal microbiome(IM) is altered in patients with cirrhosis,and emerging literature suggests that this impacts on the development of complications.The Pub Med database was searched from January 2000 to May 2015 for studies and review articles on the composition,pathophysiologic effects and therapeutic modulation of the IM in cirrhosis.The following combination of relevant text words and MeS H terms were used,namely intestinal microbiome,microbiota,or dysbiosis,and cirrhosis,encephalopathy,spontaneous bacterial peritonitis,hepatorenal syndrome,variceal bleeding,hepatopulmonary syndrome,portopulmonary hypertension and hepatocellular carcinoma.The search results were evaluated for pertinence to the subject of IM and cirrhosis,as well as for quality of study design.The IM in cirrhosis is characterized by a decreased proportion of Bacteroides and Lactobacilli,and an increased proportion of Enterobacteriaceae compared to healthy controls.Except for alcoholic cirrhosis,the composition of the IM in cirrhosis is not affected by the etiology of the liver disease.The percentage of Enterobacteriaceae increases with worsening liver disease severity and decompensation and is associated with bacteremia,spontaneous bacterial peritonitis and hepatic encephalopathy.Lactulose,rifaximin and Lactobacillus-containing probiotics have been shown to partial y reverse the cirrhosis associated enteric dysbiosis,in conjunction with improvement in encephalopathy.The IM is altered in cirrhosis,and this may contribute to the development of complications associated with end-stage liver disease.Therapies such as lactulose,rifaximin and probiotics may,at least partially,reverse the cirrhosisassociated changes in the IM.This,in turn,may prevent or alleviate the severity of complications. | Mamatha Bhat Bianca M Arendt Venkat Bhat Eberhard L Renner Atul Humar Johane P Allard | 2016 | World Journal of Hepatology2016，8，27： | 13 |
| 3 | Liver transplantation and non-alcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD) is an important health problem worldwide. NAFLD encompasses a histological spectrum ranging from bland liver steatosis to severe steatohepatitis(nonalcoholic steatohepatitis, NASH) with the potential of progressing to cirrhosis and its associated morbidity and mortality. NAFLD is thought to be the hepatic manifestation of insulin resistance(or the metabolic syndrome); its prevalence is increasing worldwide in parallel with the obesity epidemic. In many developed countries, NAFLD is the most common cause of liver disease and NASH related cirrhosis is currently the third most common indication for liver transplantation. NASH related cirrhosis is anticipated to become the leading indication for liver transplantation within the next one or two decades. In this review, we discuss how liver transplantation is affected by NAFLD, specifically the following:(1) the increasing need for liver transplantation due to NASH;(2) the impact of the increasing prevalence of NAFLD in the general population on the quality of deceased and live donor livers available for transplantation;(3) the long term graft and patient outcomes after liver transplantation forNASH,and finally;and(4)the de novo occurrence of NAFLD/NASH after liver transplantation and its impact on graft and patient outcomes. | Petros Zezos Eberhard L Renner | 2014 | World Journal of Gastroenterology2014，20，42： | 12 |
| 4 | Neurochemistry as a bridge between morphology and behavior: Perspectives on aggression in insects显示文摘 | Andrew N. BUBAK Jaime L. GRACE Michael J. WATT Kenneth J. RENNER John G. SWALLOW | 2014 | Current Zoology2014，60，6： | 5 |
| 5 | The Gnetales: Recent insights on their morphology, reproductive biology, chromosome numbers, biogeography, and divergence times显示文摘Ephedra, Gnetum,和 Welwitschia 在种子工厂以内组成仍然不清楚的种系发生的关系的裸子植物顺序 Gnetales。这里,我们在我们他们的种类差异,形态学,繁殖生物学,染色体数字,和染色体尺寸的理解在过去的 10 年考察进步,加亮在甚至为能在保存材料被学习的特点的种类的采样的不平坦,例如花粉形态学。我们包括分发地图和特色的原来的插图,并且指定哪个种类组或地理区域是 undersampled。 | Stefanie M. Ickert-Bond Susanne S. Renner | 2016 | Journal of Systematics and Evolution2016，54，1： | 4 |
| 6 | Biparental behavior in the burying beetle Nicrophorus orbicollis: a role for dopamine?显示文摘 | S. Carmen PANAITOF Jazmine D. W. YAEGER Jarod P. SPEER Kenneth J. RENNER | 2016 | Current Zoology2016，62，3： | 3 |
| 7 | Recurrence of autoimmune liver diseases after liver transplantation显示文摘Liver transplantation(LT) is the most effective treatment modality for end stage liver disease caused by many etiologies including autoimmune processes. That said, the need for transplantation for autoimmune hepatitis(AIH) and primary biliary cirrhosis(PBC), but not for primary sclerosing cholangitis(PSC), has decreased over the years due to the availability of effective medical treatment. Autoimmune liver diseases have superior transplant outcomes than those of other etiologies. While AIH and PBC can recur after LT, recurrence is of limited clinical significance in most, but not all cases. Recurrent PSC, however, often progresses over years to a stage requiring re-transplantation. The exact incidence and the predisposing factors of disease recurrence remain debated. Better understanding of the pathogenesis and the risk factors of recurrent autoimmune liver diseases is required to develop preventive measures. In this review, we discuss the current knowledge of incidence, diagnosis, risk factors, clinical course, and treatment of recurrent autoimmune liver disease(AIH, PBC, PSC) following LT. | Nabiha Faisal Eberhard L Renner | 2015 | World Journal of Hepatology2015，7，29： | 3 |
| 8 | 跨声速流自发凝结水滴的测量显示文摘应用基于多波长消光法原理发展的光学探针,测量了跨声速风洞中不同马赫数湿空气流自发凝结形成的水滴尺寸及浓度。 | 蔡小舒 Renner,M | 1999 | 流体力学实验与测量1999，13，3： | 3 |
| 9 | Virus-Induced Gene Silencing in the Culinary Ginger (Zingiber officinale): An Effective Mechanism for Down-Regulating Gene Expression in Tropical Monocots显示文摘导致病毒的基因 silencing (VIGS ) 被显示了有效为短暂在植物到的基因表示击倒在开发和压力相关的回答分析特定的基因的效果。VIGS 很好在 Solanaceae, Brassicaceae, Leguminaceae,和 Poaceae 以内为模型系统和庄稼的研究被建立,但是仅仅最近被用于住在这些家庭外面的植物。这里,我们证明了那个大麦条纹马赛克病毒(BSMV ) 能在 Zingiberaceae 以内感染二种,并且那 BSMVVIGS 能被用于明确地在厨房的生姜姜 officinale 的下面调整 phytoene desaturase。这些结果建议到除谷物以外的 monocots 的 BSMVVIGS 的扩展为许多重要适度、热带的庄稼种类的指导基因分析有潜力。 | Tanya Renner Jennifer Bragg Heather E. Driscoll Juliana Cho Andrew O. Jackson Chelsea D. Specht | 2009 | Molecular Plant2009，2，5： | 2 |
| 10 | The long‐term efficacy of nucleos(t)ide analog plus a year of low‐dose HBIG to prevent HBV recurrence post‐liver transplantation显示文摘 | Tomohiro Tanaka Ali Benmousa Max Marquez George Therapondos Eberhard L. Renner Leslie B. Lilly | 2012 | Clin Transplant2012，，5： | 2 |
| 11 | Prevalence of flat lesions in a large screening population and their role in colonoscopy quality improvement显示文摘 | K. Reinhart C. Bannert D. Dunkler P. Salzl M. Trauner F. Renner P. Knoflach A. Ferlitsch W. Weiss M. Ferlitsch | 2013 | Endoscopy2013，，05： | 2 |
| 12 | Anti-CD16/CD30 bispecific antibody treatment for Hodgkin's disease: role of infusion schedule and costimulation with cytokines 显示文摘 | Hartmann F Renner C Jung W ET aI | 2001 | Clinical Cancer Research2001，7，7： | 1 |
| 13 | Fracture - dislocation of the lumbosacral spine:case report and review of the literature 显示文摘 | Dahners LE Renner JB | 1992 | J Trauma1992，33，： | 1 |
| 14 | Three-dimensional in vivo measurement of lumbar spine segmental motion 显示文摘 | Ochia RS Inoue N Renner SM | 2006 | Spine2006，31，18： | 1 |
| 15 | Novel model to analyze the effect of a large compressive follower pre-load on range of motions in a lumbar spine显示文摘 | Renner SM Natarajan RN Patwardhan AG | 2007 | J Biomech2007，40，6： | 1 |
| 16 | The management of Complex re-nal stones显示文摘 | Rassweiler JJ Renner G Eisenberger F | 2000 | BJU International2000，8，： | 1 |
| 17 | The Internal Transcribed Spacer of Nuclear Nibosomal DNA in the Gymnosperm Gnetum显示文摘 | WON H RENNER S S | 2005 | Mol Phylogenet Evol2005，36，3： | 1 |
| 18 | Augmentation of pedicle screw fixation strength using an injectable calcium phosphate cement as a function of injection timing and method 显示文摘 | Renner SM Lim TH Kim WJ | 2004 | Spine (Pbila Pa 1976)2004，29，11： | 1 |
| 19 | Role of p glycoprotein inhibition for drug interactions: evi- dence from in vitro and pharmacoepidemiological studies显示文摘 | Eberl S Renner B Neubert A | 2007 | Clin Pharmacokinet2007，46，12： | 1 |
| 20 | Conflict Brewing Over Herbicide's Link to Frog Defoymities显示文摘 | Renner R | | 0，，： | 1 |
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