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21篇 您的检索式:作者名="Remedios A"
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1Non invasive blood flow measurement in cerebellum detects minimal hepatic encephalopathy earlier than psychometric tests显示文摘AIM: To assess whether non invasive blood flow measurement by arterial spin labeling in several brain regions detects minimal hepatic encephalopathy. METHODS: Blood flow(BF) was analyzed by arterial spin labeling(ASL) in different brain areas of 14 controls, 24 cirrhotic patients without and 16 cirrhotic patients with minimal hepatic encephalopathy(MHE). Images were collected using a 3 Tesla MR scanner(Achieva 3T-TX, Philips, Netherlands). Pulsed ASL was performed. Patients showing MHE were detected using the battery Psychometric Hepatic Encephalopathy Score(PHES) consisting of five tests. Different cognitive and motor functions were also assessed: alterations in selective attention were evaluated using the Stroop test. Patients and controls also performed visuo-motor and bimanual coordination tests. Several biochemical parameters were measured: serum pro-inflammatory interleukins(IL-6 and IL-18), 3-nitrotyrosine, cGMP and nitrates+nitrites in plasma, and blood ammonia. Bivariate correlations were evaluated.RESULTS: In patients with MHE, BF was increased in cerebellar hemisphere(P = 0.03) and vermis(P = 0.012) and reduced in occipital lobe(P = 0.017). BF in cerebellar hemisphere was also increased in patients without MHE(P = 0.02). Bimanual coordination was impaired in patients without MHE(P = 0.05) and much more in patients with MHE(P < 0.0001). Visuo-motor coordination was impaired only in patients with MHE(P < 0.0001). Attention was slightly affected in patients without MHE and more strongly in patients with MHE(P< 0.0001). BF in cerebellar hemisphere and vermis correlated with performance in most tests of PHES [(number connection tests A(NCT-A), B(NCT-B)and line tracing test] and in the congruent task of Stroop test. BF in frontal lobe correlated with NCT-A. Performance in bimanual and visuomotor coordination tests correlated only with BF in cerebellar hemisphere. BF in occipital lobe correlates with performance in the PHES battery and with CFF. BF in cerebellar hemisphere correlates with plasma cGMP and nitric oxide(NO) metabolites. BF in vermis cerebellar also correlates with NO metabolites and with 3-nitrotyrosine. IL-18 in plasma correlates with BF in thalamus and occipital lobe.CONCLUSION: Non invasive BF determination in cerebellum using ASL may detect MHE earlier than the PHES. Altered NO-cGMP pathway seems to be associated to altered BF in cerebellum.Vicente Felipo Amparo Urios Carla Giménez-Garzó Omar Cauli Maria-Jesús Andrés-Costa Olga González Miguel A Serra Javier Sánchez-González Roberto Aliaga Remedios Giner-Durán Vicente Belloch Carmina Montoliu 2014World Journal of Gastroenterology2014,20,33:12
2Bone and bone healing 显示文摘Remedios A 1999Vet Clin North Am Small Anita Pract1999,29,5:1
3Study of the antioxidant power of brandies and vinegars derived from sherry wines and correlation with their content in polyphenols显示文摘ANGELES M A REMEDIOS C M CARMEN R 2004Food Res Int2004,37,:1
4Morphology and protein content of hepatocytes in type I diabetic rats submitted to physical exerci- ses 显示文摘Remedio RN Castellar A Barbosa RA 2011Micron2011,42,5:1
5Radiological and clinical recurrence of giant-cell tumor of bone after the use of cement显示文摘Remedios D Saiffudin A Pringle J 1997J Bone Joint Surg(Br)1997,79,:1
6Radiological and clinical recurrence of giant-cell tumor of bone after the use of cement显示文摘Remedios D Saiffudion A Pringle J 1997J Bone Joint Surg(Br)1997,79,:1
7Collagen and reticular fibers in left ventricular muscle in diabetic rats: physical exercise prevents its changes显示文摘Castellar A Remedio R N Barbosa R A 2011Tissue Cell2011,43,1:1
8Laparoscopicapproaches to the lumbar vertebrae: an anatomic study using aporcine model显示文摘Southerland S R Remedios A M McKerrell J G 1995Spine1995,20,:1
9Complex intracranial arterial anatomy in swine is unsuitable for cerebral infarction projects显示文摘 Matte G Remedios A 2004Can Assoc Radiol J2004,55,:1
10Collagen and reticular fibers in left ventricular muscle in diabetic rats:physical exercise prevents its changes显示文摘Castellar A Remedio RN Barbosa RA 2011Tissue Cell2011,43,1:1
11Thoracodorsal and caudal superficial epigastric axial pattern skin flaps in cats显示文摘Remedios A M Bauer M S Bowen C V 1989Vet Surg1989,18,:1
12Optimisation of headspace solid-phase microextraction for the analysis of volatile phenols in wine显示文摘Remedios Castro Mej??as Ramón Natera Mar??n Ma de Valme Garc??a Moreno Carmelo Garc??a Barroso 2003Journal of Chromatography A2003,,1:1
13Ultrasound-assisted method for determination of chemical oxygen demand显示文摘Canals A del Remedio Hemaodez M 2002Anal Bioanal Chem2002,374,6:1
14Effect of rice lines transformed with Bacillus thuringiensis toxin genes on the brown plant hopper and its predator Cyrtorhinus lividi pennies 显示文摘CARMENCITA C B REMEDIOS M A MICHAEL B C 2002Entomol Exp Appl2002,102,:1
15Actin binding proteins: regulation of cytoskeletal microfilaments 显示文摘Remedios C G D Chhabra D Dedova I V Berry D A Kekic M Tsubakihara M Nosworthy N J 2003Physiological Re- views2003,83,2:1
16Complex intracranial arterial anatomy in swine is unsuitable for cerebral infarction projects显示文摘Burbridge B Matte G Remedios A 2004Can Assoc Radiol J2004,55,5:1
17Radiological and clinical re-currence of giant-cell tumour of bone after the use of cement显示文摘Remedios D Saifuddin A Pringle J 0,,01:1
18The interactome of LIM domain proteins: The contributions of LIM domain proteins to heart failure and heart development显示文摘Li A Ponten F dos Remedios CG 2012Protemics2012,12,2:1
19The pathogenesis and diagnosis of canine hip dysplasia: A review 显示文摘Fries C L Remedios A M 1995The Canadian Veterinary Journal1995,36,:1
20Complex intracranial arterial anatomy in swine is unsuitable for cerebral infarction projects显示文摘Burbridge B Matte G Remedios A 2004JACR2004,55,:1
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