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29篇 您的检索式:作者名="Reig N"
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1Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation显示文摘AIM:To evaluate the long-term results of conventional chemoradiotherapy and laparoscopic mesorectal excision in rectal adenocarcinoma patients without adjuvant therapy.METHODS:Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy.Laparoscopic surgery was planned after 5-8 wk.Patients diagnosed with ypT0N0 stage cancer were not treated with adjuvant therapy according to the protocol.Patients with ypT1-2N0 or ypT3-4 or N+were offered 5-fluorouracil-based adjuvant treatment on an individual basis.An external cohort was used as a reference for the findings.RESULTS:One hundred and seventy six patients were treated with induction chemoradiotherapy and 170underwent total mesorectal excision.Cancer staging of ypT0N0 was achieved in 26/170(15.3%)patients.After a median follow-up of 58.3 mo,patients withypT0N0 had five-year disease-free and overall survival rates of 96%(95%CI:77-99)and 100%,respectively.We provide evidence about the natural history of patients with localized rectal cancer achieving a complete response after preoperative chemoradiation.The inherent good prognosis of these patients will have implications for clinical trial design and care of patients.CONCLUSION:Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team.Xabier García-Albéniz Rosa Gallego Ralf Dieter Hofheinz Gloria Fernández-Esparrach Juan Ramón Ayuso-Colella Josep Antoni Bombí Carles Conill Miriam Cuatrecasas Salvadora Delgado Angels Ginés Rosa Miquel Mario Pagés Estela Pineda Verónica Pereira Aarón Sosa Oscar Reig Iván Victoria Luis Feliz Antonio María de Lacy Antoni Castells Iris Burkholder Andreas Hochhaus Joan Maurel 2014World Journal of Gastroenterology2014,20,42:5
2The role of the inflamma- some in cellular responses to toxins and bacterial effectors 显示文摘Freche B Reig N van der Goot FG 2007Semin lmmunopathol2007,29,3:1
3Predictors of Acute Esophagitis in Lung Cancer Patients Treated With Concurrent Three-Dimensional Conformal Radiotherapy and Chemotherapy显示文摘Núria Rodríguez Manuel Algara Palmira Foro Marti Lacruz Anna Reig Ismael Membrive Joan Lozano José Luis López Jaime Quera Enric Fernández-Velilla Xavier Sanz 2009International Journal of Radiation Oncology, Biology, Physics2009,,:1
4Low-pressure Synthesis and Bridgman Growth of Hg1-xMnx Te显示文摘Reig C Sochinskii N V 1999Journal of Crystal Growth1999,197,:1
5Anthrax toxin: the long and winding road that leads to the kill 显示文摘Abrami L Reig N van der Goot FG 2005Trends Microbiol2005,13,2:1
6Anthrax toxin: the long and winding road that leads to the kill 显示文摘Abrami L Reig N vander Goot FG 2005Trends Microbiol2005,13,2:1
7显示文摘Reig C Sochinskii N V Munoz V 1999J Cryst Growth1999,197,:1
8The light subunit of system bo, + is fully functional in the absence of the heavy subunit 显示文摘REIG N CHILLAR N J BARTOCCIONI P 2002The EMBO Journal2002,21,:1
9Prevention of acute radiation enteritis:efficacy and tolerance of glutamine 显示文摘MEMBRIVE CONEJO I REIG CASTILLEJO A RODRIGUEZ de DIOS N et ai 2011Clin Transl Oncol2011,13,:1
10In vitro effects of SIKVAV retro and retro-enantio analogues on tumor metastatic events显示文摘Alminana N Grau-Oliete M R Reig F 2004Peptides2004,25,2:1
11Arterial vascularization of the human moderator band:an analysis of this structure ' s role as a collateral circulation route显示文摘Reig J Alberti N Petit M 0,,04:1
12Bivariate Nakagami-m distribution with arbitrary fading parameters 显示文摘Reig J Rubio L Cardona N 2002Electronics Letters2002,38,25:1
13Anthrax toxin: the long and winding road that leads to the kill 显示文摘Abrami L Reig N vander Goot FG 2005Trends Microbiol2005,13,2:1
14Non-invasive diagnosis of hepatocellular carcinoma ?2<ce:hsp sp='0.25'/>cm in cirrhosis. Diagnostic accuracy assessing fat, capsule and signal intensity at dynamic MRI显示文摘Jordi Rimola Alejandro Forner Silvia Tremosini Maria Reig Ramón Vilana Luis Bianchi Carlos Rodríguez-Lope Manel Solé Carmen Ayuso Jordi Bruix 2012Journal of Hepatology2012,,6:1
15Is pulsed radiofrequency a neuromodulation technique?显示文摘Abejón D Reig E 2003Neuromodulation2003,6,1:1
16The light subunit of system b('+ ) is fully functional in the ab- sence of the heavy subunit 显示文摘Reig N Chillaron J Bartoccioni P 2002EMBO J2002,21,18:1
17The light subunit of system b'': + is fully functional in the absence of the heavy subunit显示文摘REIG N CHILLARONJ BARTOCCIONI P 2002The EMBOJournal2002,21,:1
18Bivariate Nakagami-m dis- tribution with arbitrary fading parameters 显示文摘Reig J Rubio L Cardona N 2002Electronics Letters2002,38,25:1
19Prevention of acute radiation enteritis:efficacy and tolerance of glutamine显示文摘Membrive Conejo I Reig Castillejo A Rodríguez de Dios N 2011Clin Transl Oncol2011,13,10:1
20Prevention of acute radiation enteritis:efficacy and tolerance of gluta- mine显示文摘Membrive Conejo I Reig Castillejo A Rodriguez de Dios N etal 2011Clin Transl Oncol2011,13,10:1
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