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| 1 | Measurement uncertainty in pharmaceutical analysis and its application显示文摘The measurement uncertainty provides complete information about an analytical result. This is very important because several decisions of compliance or non-compliance are based on analytical results in pharmaceutical industries. The aim of this work was to evaluate and discuss the estimation of uncertainty in pharmaceutical analysis. The uncertainty is a useful tool in the assessment of compliance or non-compliance of in-process and final pharmaceutical products as well as in the assessment of pharmaceutical equivalence and stability study of drug products. | Marcus Augusto Lyrio Traple Alessandro Morais Saviano Fabiane Lacerda Francisco Felipe Rebello Lourencon | 2014 | Journal of Pharmaceutical Analysis2014,4,1: | 8 |
| 2 | Differences in viral kinetics between genotypes 1 and 3 of hepatitis C virus and between cirrhotic and non-cirrhotic patients during antiviral therapy显示文摘AIM: To evaluate the impact of hepatitis C virus (HCV) infection with genotype 1 or 3 and the presence or absence of liver cirrhosis (LC) in the early viral kinetics response to treatment. METHODS: Naive patients (n = 46) treated with interferon-α (IFN-α) and ribavirin and followed up with frequent early HCV-RNA determinations were analysed. Patients were infected with genotype 1 (n = 28, 7 with LC) or 3 (n = 18, 5 with LC). RESULTS: The fi rst phase decline was larger in geno- type 3 patients than in genotype 1 patients (1.72 vs 0.95 log IU/mL, P < 0.001). The second phase slope decline was also larger in genotype 3 patients than in genotype 1 patients (0.87 vs 0.15 log/wk, P < 0.001). Differences were found in both cirrhotic and non-cirrhotic patients. Genotype 1 cirrhotic patients had a slower 2nd phase slope than non-cirrhotic patients (0.06 vs 0.18 log/wk, P < 0.02). None of genotype 1 cirrhotic patients had a 1st phase decline larger than 1 log (non-cirrhotic patients: 55%, P < 0.02). A similar trend toward a slower 2nd phase slope was observed in genotype 3 cirrhotic pa- tients but the 1st phase slope decline was not different. Sustained viral response was higher in genotype 3 pa- tients than in genotype 1 patients (72% vs 14%, P < 0.001) and in genotype 1 non-cirrhotic patients than in genotype 1 cirrhotic patients (19% vs 0%). A secondphase decline slower than 0.3 log/wk was predictive of non-response in all groups. CONCLUSION: Genotype 3 has faster early viral decline than genotype 1. Cirrhosis correlates with a slower 2nd phase decline and possibly with a lower 1st phase slope decline in genotype 1 patients. | José Eymard Medeiros-Filho Isabel Maria Vicente Guedes de Carvalho Mello Joo Renato Rebello Pinho Avidan U Neumann Fernanda de Mello Malta Luiz Caetano da Silva Flair José Carrilho | 2006 | World Journal of Gastroenterology2006,12,45: | 3 |
| 3 | Collusion in uniform-price auctions: Experimental evidence and implications for treasuryauctions 显示文摘 | GOSWAMI G NOE T REBELLO M | 1996 | Rev Financ Studies1996,9,3: | 1 |
| 4 | Collusion in uniform-price auctions:Experimental evidence and implications for treasury auctions显示文摘 | Goswami Rebello | | 0,,09: | 1 |
| 5 | Renegotiation,Investment Horizons and Managerial Discretion显示文摘 | Noe M J Rebello | | 0,,06: | 1 |
| 6 | The inspection station location problem in hazardous materials transportation: some heuristics and bound 显示文摘 | REBELLO R AGNETIS A | 1995 | INFOR1995,33,2: | 1 |
| 7 | Integrin expression in squamous neoplasia of the cervix显示文摘 | HUGHES D E REBELLO G AL-NAFUSSI A | 1994 | J Pathol1994,173,: | 1 |
| 8 | Connecting bar for hip spica reinforcement:dose it help? 显示文摘 | Rebello G Joseph B Chincholkar A | 2004 | J Pediatr Orthop B2004,13,5: | 1 |
| 9 | Pulmonary histological appearances in fatal paraquat poisoning显示文摘 | Rebello G Mason JK | 1978 | Histopathology1978,2,1: | 1 |
| 10 | Altered circulating neurokinin B (NKB)levels are not due to sequence variants in the encoding genes 显示文摘 | Tofa KC Gebhardt S Rebello G | 2008 | Eur J Obstet Gynecol Reprod Biol2008,140,1: | 1 |
| 11 | 6H silicon carbide MOSFET modeling for high temperature analogue integrated circuits (25 ~ 500 ℃)显示文摘 | Rebello N S Shoucair F S Palmour J W | 1996 | IEE Proc-circuits Devices Syst1996,143,2: | 1 |
| 12 | Surgical dislocation in the management of pediatric and adolescent hip deformity显示文摘 | Rebello G Spencer S Millis MB | | 0,,03: | 1 |
| 13 | Treatment of is- chemic stroke with r-tPA:implementation challenges in a tertiary hospital in Brazil显示文摘 | Tosta ED Rebello LC Almeida SS | 2014 | Arq Neuropsiquiatr2014,72,5: | 1 |
| 14 | Corporate financing: An artificial agent-based analysis 显示文摘 | Noe T H Rebello M J Wang J | 2003 | Journal of Finance2003,58,3: | 1 |
| 15 | Tuning hole mobility in InP nanowires显示文摘 | REBELLO M DIAS S PICININ A | 2012 | Appl Phys Lett2012,101,18: | 1 |
| 16 | Corporate board composition,protocols,and voting behavior:experimental evidence显示文摘 | Gillette A B Noe T H Rebello M J | 2003 | Journal of Finance2003,58,5: | 1 |
| 17 | The evolution of security designs 显示文摘 | Noe T H Rebello M J Wang J | 2006 | Journal of Finance2006,61,5: | 1 |
| 18 | Down-regulation of endothelin receptor in the ventrolateral medulla of spontaneously hypertensive rats显示文摘 | GULATI A REBELLO S | 1991 | Life Sci1991,48,12: | 1 |
| 19 | 6H-Silicon carbide MOSFET modeling for high temperature analogue integrated circuits (25-500 ℃)显示文摘 | REBELLO N S SHOUCAIR F S PALMOUR J W | 1996 | IEE Proc Circ Dev Syst1996,143,2: | 1 |
| 20 | Intestinal OATP1 A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects 显示文摘 | Rebello S Zhao S Hariry S | 2012 | Eur J Clin Pharmacol2012,68,5: | 1 |