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| 1 | 利用二维应变定量检测整体和局部心肌功能:在肥厚型心肌病中的应用显示文摘OBJECTIVES: Recently, a novel method to measure strain from standard two-dimensional images has been developed. Our goal was to characterize global and regional systolic function abnormalities using this technique in patients with hypertrophic cardiomyopathy(HCM). BACKGROUND: Strain has been proposed as a sensitive tool to detect early systolic function abnormalities in HCM. However, the clinical application of conventional Doppler-derived strain has been limited by poor reproducibility and angle dependency. METHODS: Echocardiographic examinations were performed in 26 patients with nonobstructive HCM and 45 healthy subjects. Using a dedicated software package, bidimensional acquisitions were analyzed to measure longitudinal and transverse strain in apical views and circumferential and radial strain in parasternal short-axis view. RESULTS: Despite apparently normal left ventricular systolic function, all components of strain were significantly reduced in HCM. Average longitudinal, transverse, circumferential, and radial strain in patients with HCM and controls were -15.1± 6.2% versus -20.3± 5.6% , 23.3± 17.0% versus 27.2± 14.9% ,-16.8± 7.1% versus 19.6± 5.2% , and 25.2± 13.9% versus 36.8± 17.2% , respectively(all p< 0.001). In patients with asymmetrical HCM, longitudinal septal strain was significantly lower than for other left ventricular segments combined:-9.2± 4.7% versus-12.7± 7.1% (p=0.001). Average interobserver and intraobserver variabilities were 11% and 11.3% , respectively. CONCLUSIONS: Two-dimensional strain is a new simple, rapid, and reproducible method to measure different components of systolic strain. This technique identified early abnormalities in patients with HCM that have apparently normal left ventricular systolic function. | Serri K. Reant P. Lafitte M. S. Lafitte 孙凯 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，2，8： | 3 |
| 2 | Evaluation of global left ventricular systolic function using three-dimensional echocardiog- raphy speckle-tracking strain parameters 显示文摘 | REANT P BARBOT L TOUCHE C | 2012 | J Am Soc Echocar- diogr2012，25，1： | 1 |
| 3 | Global and regional myocardial function quantification by two-dimensional strain ; application in hypertrophic cardiomyopathy 显示文摘 | Serri K Reant P Lafitte M | 2006 | Am Coll Cardiol2006，47，6： | 1 |
| 4 | Global and regional myocardial function is quantification by twodimensional strain; application in hypertrophic cardiomyopathy 显示文摘 | SERRI K REANT P LAFITrE M | 2006 | Am Coil Cardiol2006，47，6： | 1 |
| 5 | Experimental validation of circumferential,longitudinal,and radial 2-dimensional strain during dobutamine stress echocardiography in ischemic conditions显示文摘 | Reant P Labrousse L Lafitte S | | 0，，02： | 1 |
| 6 | Experimental validation of cir- cumferential, longitudinal, and radial 2 -dimensional strain during dobutamine stress echocardiography in ischemic conditions 显示文摘 | Reant P iabmusse L Lafitte S | 2008 | Journal of the American College of Cardiology2008，51，2： | 1 |
| 7 | Early detection of left ven- tricular systolic dysfunction using two dimensional speckle tracking strain evaluation in healthy subjects after acute alcohol intoxication 显示文摘 | Reant P Chasseriaud W Pillois X | 2012 | Echocardiography2012，29，8： | 1 |
| 8 | Evaluation of global left ventricular systolic function using three-dimensional echocardiography speckle-tracking strain parameters显示文摘 | Reant P Barbot L Touche C | 2012 | J Am Soc Echocardiogr2012，25，1： | 1 |
| 9 | Reverse remodeling of the left cardiac chambers after catheter ablation after 1 year in a series of patients with isolated atrial fibrillation显示文摘 | REANT P LAFITTE S JAIS P | 2005 | Circulation2005，112，： | 1 |
| 10 | Evaluation of global left ventricular systolic function using three-dimensional echocardiography speckle-tracking strain parameters 显示文摘 | Reant P Barbot L Touche C | 2012 | JAm SDC Echocardiogr2012，25，1： | 1 |
| 11 | Reverse remodeling of the left cardiacchambers after catheter ablation after1year in a series of patients with isolated atrial fibrillation显示文摘 | Reant P Lafitte S Jas P | 2005 | Circulation2005，112，19： | 1 |
| 12 | Global and regional myocardial function quantification by two-dimensional strain:application in hypertrophic cardiomyopathy显示文摘 | Serri K Reant P Lafitte M | 2006 | J Am Coll Cardiol2006，47，： | 1 |
| 13 | Reverse remodeling of the left cardiac chambers after catheter ablation after 1 year in a series of patients with isolated atrial fibrillation显示文摘 | Reant P Lafitte S Jais P | | 0，，： | 1 |
| 14 | Identification and characteriza- tionof super-responders after cardiac resynchronization therapy 显示文摘 | Reant P Zaroui A Donal E | 2010 | Am J Cardiol2010，105，： | 1 |
| 15 | Global and regional myocardial function quantification by two-dimentional strain:applicationin hyper-trophic cardiomyopathy显示文摘 | Serri K Reant P Lafitte M | 2006 | J Am Coll Cardiol2006，47，6： | 1 |
| 16 | An ultrasound speckle tracking (two_dimensional) analysis of myocardial defonnatbn in professional soccer players compared with healthy subjects and hypertrophic eardiomyopathy 显示文摘 | RICHAND V LAFITFE S REANT P | 2007 | Am J eardiol2007，100，1： | 1 |
| 17 | An ultrasound speckle tracking(two-dimensional strain) analysis of myocardial deformation in professional soccerp layers compared with healthy subjects and hypertrophic cardiomyopathy显示文摘 | Richand V Lafitte S Reant P | 2007 | Am J Cardio l2007，100，1： | 1 |
| 18 | Effects of right, left, and- biventricular pacing on myocardial perfusion in ischemic conditions 显示文摘 | Lafitte S Reant P Labrousse L | 2006 | J Cardiovasc Electrophysiol2006，17，10： | 1 |
| 19 | Global and regional myocardial function quantification by two-dimensional strain:application in hypertrophic cardiomyopathy显示文摘 | Serri K Reant P Lafitte M | 2006 | J Am Coll Cardiol2006，47，6： | 1 |
| 20 | Global and regional my- ocardial function quantification by two-dimensional strain: application in hypertrophic cardiomyopathy 显示文摘 | Serri K Reant P Lafitte M | 2006 | J Am Coll Cardiol2006，47，6： | 1 |
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