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| 1 | Critical analysis of key determinants and barriers to digital innovation adoption among architectural organizations显示文摘 | Runddy Ramilo Mohamed Rashid Bin Embi | 2014 | Frontiers of Architectural Research2014，3，4： | 2 |
| 2 | Association of gene and protein expression and genetic polymorphism of CC chemokine ligand 4 in colorectal cancer显示文摘BACKGROUND Leukocytes,such as T cells and macrophages,play an important role in tumorigenesis.CC chemokine ligand(CCL)4,which is produced by lymphocytes and macrophages,has been found to be expressed in the mucosa of the gastrointestinal tract and is a potent chemoattractant for various leukocytes.AIM To examine CCL4 expression and its genetic polymorphism rs10491121 in patients with colorectal cancer(CRC)and evaluate their prognostic significance.METHODS Luminex technology was used to determine CCL4 Levels in CRC tissue(n=98),compared with paired normal tissue,and in plasma from patients with CRC(n=103),compared with healthy controls(n=97).Included patients had undergone surgical resection for primary colorectal adenocarcinomas between 1996 and 2019 at the Department of Surgery,Ryhov County Hospital,Jönköping,Sweden.Reverse transcription quantitative PCR was used to investigate the CCL4 gene expression in CRC tissue(n=101).Paired normal tissue and TaqMan single nucleotide polymorphism assays were used for the CCL4 rs10491121 polymorphism in 610 CRC patients and 409 healthy controls.RESULTS The CCL4 protein and messenger RNA expression levels were higher in CRC tissue than in normal paired tissue(90%,P<0.001 and 45%,P<0.05,respectively).CRC tissue from patients with localized disease had 2.8-fold higher protein expression levels than that from patients with disseminated disease.Low CCL4 protein expression levels in CRC tissue were associated with a 30%lower cancer-specific survival rate in patients(P<0.01).The level of plasma CCL4 was 11%higher in CRC patients than in healthy controls(P<0.05)and was positively correlated(r=0.56,P<0.01)with the CCL4 protein level in CRC tissue.The analysis of CCL4 gene polymorphism rs10491121 showed a difference(P<0.05)between localized disease and disseminated disease in the right colon,with a dominance of allele A in localized disease.Moreover,the rate of the A allele was higher among CRC patients with mucinous cancer than among those with nonmucinous cancer.CONCLUSION The present study indicates that the CRC tissue levels of CCL4 and CCL4 gene polymorphism rs10491121,particularly in the right colon,are associated with clinical outcome in CRC patients. | Levar Shamoun Kalle Landerholm Amanda Balboa Ramilo Roland E Andersson Jan Dimberg Dick Wågsäter | 2021 | World Journal of Gastroenterology2021，27，30： | 2 |
| 3 | Respiratory syneytial virus: how, why and what to do显示文摘 | RODRIGUEZ R RAMILO O | 2014 | The Journal of Infection2014，68，1： | 1 |
| 4 | E-government in Practice:An Analysis of Web Site Orientation to the Citizens in Spanish Municipalities显示文摘 | RAMILO M C | 2003 | The International Journal of Public Sector Management2003，16，3： | 1 |
| 5 | Phylogenetie specificity of cholinergic ligands: alpha-conotoxin SI 显示文摘 | Zafaralla G C Ramilo C Gray W R | 1988 | Biochem1988，27，71： | 1 |
| 6 | The relationship between RSV bronchiolitis and recurrent wheezing:The chicken and the egg显示文摘 | Bont L Ramilo O | 2011 | Early Hum Dev2011，871，： | 1 |
| 7 | Cerebrospinal fluid prostaglandins interleukin 1β and tumor necrosis factor in bacterial meningtis显示文摘 | Ramilo O Llorens X | 1990 | Am J Dis Child1990，144，8： | 1 |
| 8 | Concomitant re- spiratory viral infections in children with Kawasaki disease 显示文摘 | Jordan-Villegas A Chang ML Ramilo O | 2010 | Pediatr Infect Dis2010，29，8： | 1 |
| 9 | Detecting specific infec tions in children through host responses: a paradigm shift 显示文摘 | Mejias A Suarez NM Ramilo O | 2014 | Curr Opin Infect Dis2014，27，3： | 1 |
| 10 | Respiratory syncy- tial virus: old challenges and new approaches显示文摘 | Chavez-Bueno S Mejfas A Jafr: HS Ramilo O | 2005 | Pediatr Ann2005，34，1： | 1 |
| 11 | Novel alpha- and omega-conotoxins from Conus striatus venom 显示文摘 | Ramilo C A Zafaralla G C Nadasdi L | 1992 | Biochern1992，31，： | 1 |
| 12 | Cerebrospinal fluid interleukin- 1-beta and turnout necrosis factor concentrations and outcome from neonatal gram - negative enteric bacillary meningitis显示文摘 | McCracken GH Mustafa MM Ramilo O | 1989 | Pediatr Infect Dis J1989，8，： | 1 |
| 13 | Safety and pharma- cokinetics of palivizumab therapy in children hospitalized with re- spiratory syncytial virus infection 显示文摘 | Saez - Llorens X Moreno MT Ramilo O | 2004 | Pediatr Infect Dis J2004，23，8： | 1 |
| 14 | Unilateral absense of a pulmonary artery 显示文摘 | Werber J Ramilo J L London R | 1983 | Chest1983，84，： | 1 |
| 15 | Novel α-and ω-conotoxins from Conus striatus venom显示文摘 | Ramilo C A Zafaralla G C Nedasdi L | 1992 | Biochemistry1992，31，： | 1 |
| 16 | Cytotoxic effects of BADGE (bisphenol A diglycidyl ether) and BFDGE (bisphenol F diglycidyl ether) on Caco-2 cells in Vitro显示文摘 | RAMILO G VALVERDE I LAGO J JUAN M V CABADO A G | 2006 | Archives Toxicol2006，80，11： | 1 |
| 17 | Review of palivizumab in the prophylaxis of respiratory syncytial virus(RSV)in high-risk infants显示文摘 | Mejias A Ramilo O | | 0，，03： | 1 |
| 18 | Cytotoxic effects of BADGE (Bisphenol A Diglycidyl Ether) and BFDGE (Bisphenol F Diglycidyl Ether) on Caeo- 2 cells in Vitro显示文摘 | RAMILO Graciela VALVERDE Iago LAGO Jorge | 2006 | Arch Toxieol2006，80，23： | 1 |
| 19 | Concomitant re- spiratory viral infections in children with Kawasaki disease显示文摘 | Jordan-Villegas A Chang ML Ramilo O | 2010 | Pe- diatr Infect Dis J2010，29，8： | 1 |
| 20 | Toxin composition of the toxic dinoflagellate Prorocentrum lima isolated from different locations along the Galician coast (NW Spain)显示文摘 | BRAVO I FERNANDEZ ML RAMILO I MARTINEZ A | 2001 | Toxicon2001，39，： | 1 |
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