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1篇 您的检索式：作者名="Rahma Issa"

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		题名	作者	年代	出处	被引量
	1	B Cell-mediated Humoral Immunity in Chronic Hepatitis B Infection显示文摘B cell-mediated humoral immunity plays a vital role in viral infections,including chronic hepatitis B virus(HBV)infection,which remains a critical global public health issue.Despite hepatitis B surface antigen-specific antibodies are essential to eliminate viral infections,the reduced immune functional capacity of B cells was identified,which was also correlated with chronic hepatitis B(CHB)progression.In addition to B cells,T follicular helper(Tfh)cells,which assist B cells to produce antibodies,might also be involved in the process of anti-HBVspecific antibody production.Here,we provide a comprehensive review of the role of various subsets of B cells and Tfh cells during CHB progression and discuss current novel treatment strategies aimed at restoring humoral immunity.Understanding the mechanism of dysregulated B cells and Tfh cells will facilitate the ultimate functional cure of CHB patients.	Yang Li Shengxia Yin Rahma Issa Xin Tong Guiyang Wang Juan Xia Rui Huang Guangmei Chen Dan Weng Chen Chen Chao Wu Yuxin Chen	2021	Journal of Clinical and Translational Hepatology2021，9，4：	2

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