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| 1 | Unexpected alliance between syndecan-1 and innatelike T cells to protect host from autoimmune effects of interleukin-17显示文摘Innate-like T cells, namely natural killer T(NKT) and γδ T cells, play critical roles in linking innate and adaptive immune responses through rapid production of cytokines. Prominent among these cytokines is interleukin-17(IL-17), which is a potent proinflammatory cytokine that plays a critical role in host defense against fungi and extracellular bacteria. However, excessive IL-17-production promotes autoimmune diseases, including psoriasis, multiple sclerosis, rheumatoid arthritis, inflammatory bowel disease, and systemic lupus erythematosus. IL-17 has also been implicated in regulating body fat, which is highly relevant given rises in obesity and type 2 diabetes. NKT cells, γδ T cells and mucosal-associated invariant T cells(MAIT) are the major sources of IL-17 involved in protection of mucosal surfaces from opportunistic infections and causing autoimmunity when become dysregulated. Given the pathogenic effects of IL-17, efforts have been directed towards understanding mechanisms that guard against IL-17 overproduction. One novel potent mechanism is mediated by the heparan sulfate proteoglycan, syndecan-1(sdc1), which is selectively expressed by IL-17-producing subsets of NKT and γδ T cells. This unexpected role for sdc1 is uncovered by analysis of NKT and γδ T cells in sdc1-deficient mice. In this mini-review, we discuss selective expression of sdc1 by these innate T cells and consequences of its absence on IL-17 homeostasis and pathological implications. | Anil Kumar Jaiswal Mohanraj Sadasivam Abdel Rahim A Hamad | 2018 | World Journal of Diabetes2018，9，12： | 5 |
| 2 | Ly49 receptors activate angiogenic mouse DBA+ uterine natural killer cells显示文摘 | Patricia DA Lima Megan M Tu Mir Munir A Rahim Annie R Peng B Anne Croy Andrew P Makrigiannis | 2014 | Cellular & Molecular Immunology2014，11，5： | 3 |
| 3 | Current understandings of the pathogenesis of type 1 diabetes:Genetics to environment显示文摘Type 1 diabetes(T1D)is an autoimmune disease that usually strikes early in life,but can affect individuals at almost any age.It is caused by autoreactive T cells that destroy insulin-producing beta cells in the pancreas.Epidemiological studies estimate a prevalence of 1 in 300 children in the United States with an increasing incidence of 2%-5%annually worldwide.The daily responsibility,clinical management,and vigilance required to maintain blood sugar levels within normal range and avoid acute complications(hypoglycemic episodes and diabetic ketoacidosis)and long term micro-and macro-vascular complications significantly affects quality of life and public health care costs.Given the expansive impact of T1D,research work has accelerated and T1D has been intensively investigated with the focus to better understand,manage and cure this condition.Many advances have been made in the past decades in this regard,but key questions remain as to why certain people develop T1D,but not others,with the glaring example of discordant disease incidence among monozygotic twins.In this review,we discuss the field’s current understanding of its pathophysiology and the role of genetics and environment on the development of T1D.We examine the potential implications of these findings with an emphasis on T1D inheritance patterns,twin studies,and disease prevention.Through a better understanding of this process,interventions can be developed to prevent or halt it at early stages. | Adebola Matthew Giwa Rizwan Ahmed Zahra Omidian Neha Majety Kagan Ege Karakus Sarah M Omer Thomas Donner Abdel Rahim A Hamad | 2020 | World Journal of Diabetes2020，11，1： | 2 |
| 4 | 低能重离子诱导反应中轻带电粒子和蒸发剩余物的能谱(英文)显示文摘在多源理想气体模型的框架内,用一个关于末态粒子多重数分布的统一描述,研究了低能重离子诱导反应中轻带电粒子和蒸发剩余物的能谱。在同一个激发的复合核中,每个源对带电粒子和蒸发剩余物均贡献一个指数分布的能谱。计算结果与158,170,180和200MeV20Ne+12C反应中,轻带电粒子和蒸发剩余物能谱的实验结果符合。 | 吕绮雯 卫华荣 Rahim Magda A Fakhraddin S 刘福虎 | 2012 | 原子核物理评论2012，29，1： | 2 |
| 5 | Applica-tion of magneto-rheological damper for car suspension control显示文摘 | RASHID M M HUSSAIN M A RAHIM N A | 2006 | Journal of Applied Sciences2006，6，4： | 1 |
| 6 | Optimal control of a deteriorating process with a quadratic loss function显示文摘 | Al-Fawzan M A Rahim M A | 2001 | Quality and Reliability Engineering International2001，17，5： | 1 |
| 7 | Determination of an optimal setting and production run using taguchi's loss function显示文摘 | Pakkala T P M Rahim M A | 1999 | International Journal of Reliability Quality and Safety Engineering1999，6，4： | 1 |
| 8 | Effects of maintenance on eco- nomic design of an x-bar control chart显示文摘 | RAHIM M A BEN-DAYA M | 2000 | European Journal of Operation Research2000，120，1： | 1 |
| 9 | Toward a theory of managing organizational conflict显示文摘 | Rahim M A | 2002 | The International Journal of Conflict Manage- ment2002，13，3： | 1 |
| 10 | Energy savings and emissions reductions for rewinding and replacement of industrial motor显示文摘 | Hasanuzzaman M Rahim N A Saidur R Kazi S N | | 0，，01： | 1 |
| 11 | Specifieity,inhibitory, studies and oligoaseeharide fomartoin by :-Galacotsidaes form psychrotorphie Bacillus subtilis KL88显示文摘 | Khalid A A Rahim Byong H L | 1991 | J Dairy Sci1991，74，： | 1 |
| 12 | Two phase thermal transport in microgap channels: theory, experimental results, and predictive relations 显示文摘 | BAR COHEN A SHEEHAN J R RAHIM E | 2012 | Microgravity Science and Technology2012，24，1： | 1 |
| 13 | Lactobacillus acidophilus as a live vehicle for oral immunization against chicken anemia virus 显示文摘 | MOEINI H RAHIM R A OMAR A R | 2011 | Appl Mierobiol Biot2011，90，1： | 1 |
| 14 | A generalized economic model for joint determination of production run, inspection schedulecontrol chart deslgn显示文摘 | RAHIM M A BEN-DAYA M | 1998 | International Journal of Production Research1998，36，1： | 1 |
| 15 | Straight projection conflictdetection and cooperative avoidance for autonomous unmanned aircraft systems 显示文摘 | Albaker B M Rahim N A | 2009 | IEEE ICIEA2009，，： | 1 |
| 16 | Peach ripening transcriptomics unveils new and unexpected targets for the improvement of drupe quality 显示文摘 | Busatto N Rahim M A Trainotti L | 2013 | From Plant Genomics to Plant Biotechnology2013，，： | 1 |
| 17 | Specificity, inhibitory studies, and gosaccharide formation by β-galacotosidase from Psychrotrophic bacillus subtilis KL88显示文摘 | KHALID A RAHIM A LEE B H | 1991 | J Dairy Sci1991，74，6： | 1 |
| 18 | Pilot-based simplified ML and fast algorithm for frequency offset estimation in OFDMA uplink显示文摘 | Zeng Yonghong Leyman A Rahim | 2008 | IEEE Transactions on Vehicular Technology2008，57，3： | 1 |
| 19 | Effect of solid to liquid ratio on the mechanical and physical properties of fly ash geopolymer without sodium silicate 显示文摘 | Rahim R H A Azizli K A Man Z | 2014 | Process and Advanced Materials Engineering2014，625，： | 1 |
| 20 | A review on global wind energy policy显示文摘 | SAIDUR R ISLAM M R RAHIM N A | 2010 | Renewable and Sustainable Energy Reviews2010，14，7： | 1 |
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