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| 1 | Lubiprostone used with polyethylene glycol in diabetic patients enhances colonoscopy preparation quality显示文摘AIM: To assess the additive effect of lubiprostone on the quality of colon preparation in diabetics given single-dosed polyethylene glycol electrolyte(PEG)for colonoscopy.METHODS:This was an investigator-initiated,singlecenter,single-blinded prospective trial comparing the efficacy of L+PEG to PEG alone on colon preparation quality in diabetics undergoing screening colonoscopy.The study was approved by our institution’s IRB.The PEG was given as a single-dose to address patientcompliance concerns voiced by our IRB with splitdosing.All patients received only clear liquids the day prior to colonoscopy.Experimental group(Grp L)received PEG+1 dose L 2 h prior to and 2 h after PEG completion.Control group(Grp C)received only PEG the evening prior to the colonoscopy.Patients were randomly assigned to one of the 2 groups.The endoscopist was blinded to which colon prep was given and all colonoscopies were complete.Upon colonoscopy completion,the endoscopist rated the colon prep-quality by a validated 5-point Likert scale(1-excellent to 5-inadequate).RESULTS:Sixty patients were enrolled in the study;30 Grp L and 30 Grp C.Overall,patients were excluded due to study non-completion in 12(41%)Grp L and 5(17%) Grp C,P=0.04.Average colon preparation score Grp L =2.47 and Grp C=3.00,P=0.09.Although this was not statistically significant,there was a trend towards improved colon prep in Grp L.Statistical significance may have been achieved if completion rates had been similar between both study groups.CONCLUSION:Use of 2-L capsules with PEG resulted in a trend towards improved colon prep over PEG alone in diabetic patients when given as a single-dose regimen. | Erika Grigg Moonkyung C Schubert Joshua Hall Fadi Rahhal Dimple Raina Subbaramiah Sridhar Sherman M Chamberlain | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，7： | 5 |
| 2 | Hepatic failure caused by plasma cell infiltration in multiple myeloma显示文摘Although plasma cell infiltration is not rare in autopsy of patients with multiple myeloma (MM), it is very rarely detected in living patients. This is because MM rarely causes significant liver dysfunction that requires further evaluation. A 49-year-old man presented with acute renal failure and was diagnosed with kappa light chain MM stage B.Thalidomide and dexamethasone were initiated.The patient developed a continuous increase in bilirubin that led to severe cholestasis.A liver biopsy revealed plasma cell infiltration.He then rapidly progressed to liver failure and died.Treatment options are limited in MM with significant liver dysfunction.espite new drug therapies in MM,those patients with rapidly progressive liver failure appear to have a dismal outcome. | Fadi E Rahhal Robert R Schade Asha Nayak Teresa A Coleman | 2009 | World Journal of Gastroenterology2009，15，16： | 2 |
| 3 | Early hydration of portland cement with crystalline mineral additions显示文摘 | Rahhal V Talero R | 2005 | Cement Concrete Research2005，35，7： | 1 |
| 4 | Results of a second year of therapy with the 12 month histrelin implant for the treatment of central precocious puberty 显示文摘 | Rahhal S Clarke WL Kletter GB | 2009 | Int J Pediatr Endocrinol2009，，81： | 1 |
| 5 | Early hydration of Portland ce- ment with limestone mineral additions 显示文摘 | Rahhal V Talero R | 2005 | Cement and Concrete Research2005，35，7： | 1 |
| 6 | Reduction of hydrogen peroxide by the ferrous iron chelate of diethoxTphosphory-5-N-pentaacetate显示文摘 | RAHHAL S RICHTER H W | 1998 | J Am Chem Soc1998，110，： | 1 |
| 7 | Studies on the carbonaluminate formation in limestone filler-blended cements显示文摘 | Bonavetti V L Rahhal V F Irassar E F | | 0，，06： | 1 |
| 8 | Influence of two different fly ashes on the hydration of portland cements 显示文摘 | RAHHAL V TALERO R | 2004 | Journal of Thermal Analysis and Calorimetry2004，78，1： | 1 |
| 9 | Unexpected recovery of ovarian function many years after bone marrow transplantation显示文摘 | Rahhal SN Eugster EA | 2008 | J Pediatr2008，152，2： | 1 |
| 10 | Sulphate Resistance of Type V Cements with Limestone Filler and Natural Pozzolana显示文摘 | IRASSAR E F GONZaLEZ M RAHHAL V | 2000 | Cem Coner Compos2000，22，5： | 1 |
| 11 | Reduction of hydrogen peroxide by the ferrous iron chelate of diethylenetriamine-N,N,N′,N″,N″-pentaacetate显示文摘 | Rahhal S Richter H W | 1988 | J Am Chem Soc1988，110，： | 1 |
| 12 | Automated position-ing and alignment systems显示文摘 | Williams G Chalupa E Rahhal S | 2000 | SAE Transactions2000，109，11： | 1 |
| 13 | Transforming growth factor beta cooperates with persephin for dopaminergic phenotype induction显示文摘 | Roussa E Oehlke O Rahhal B | 2008 | Stem Cells2008，26，7： | 1 |
| 14 | In vivo requirement of TGF-beta/GDNF cooperativity in mouse development: focus on the neurotrophie hypothesis显示文摘 | Rahhal B Heermann S Ferdinand A | 2008 | Int J Dev Neurosei2008，，1： | 1 |
| 15 | NGF and TGF beta mRNA expression during pregnancy in a rat corneal wound healing model显示文摘 | Nieto A Casas J Rahhal SM | 2003 | Clin Exp Optom2003，86，4： | 1 |
| 16 | Studies on the Car- boaluminate Formation in Limestone Filler-Blended Cements显示文摘 | Bonavetti V L Rahhal V F Irassar E F | 2001 | Cement and Concrete Research2001，31，6： | 1 |
| 17 | The relationship between central corneal thickness and Goldmann applanation tonometry显示文摘 | Lleo A Marcos A Calatayud M Alonso L Rahhal SM Sanchis-Gimeno JA | 2003 | Clin Exp Optom2003，86，2： | 1 |
| 18 | Influence of initial curing on the properties of concrete containing limestone blended cement显示文摘 | BONAVETTI V DONZA H RAHHAL V | 2000 | Cement and Concrete Research2000，30，5： | 1 |
| 19 | Studies on the carboaluminate formation in limestone filler-blended cements显示文摘 | BONAVETTI V L RAHHAL V F IRASSAR E F | 2001 | Cem Concr Res2001，31，6： | 1 |
| 20 | Studies on the carboaluminate formation in limestone filler-blended cements显示文摘 | BONAVETTI V RAHHAL V IRASSAR E | 2001 | Cement and Concrete Research2001，31，6： | 1 |
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