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| 1 | Role of Helicobacter pylori infection in autoimmune systemic rheumatic diseases显示文摘The relationship between infection and autoimmunity has been increasingly defined over the last 20 years. The systemic rheumatic diseases are characterized by dysregulation of the immune system resulting in a loss of tolerance to self-antigen. The exact etiology for the majority of these diseases is unknown; however, a complex combination of host and environmental factors are believed to play a pivotal role. Helicobacter pylori(H. pylori) is one of the most widely studied infectious agents proposed as agents triggering autoimmune response. The persistent presence of H. pylori in the gastric mucosa results in chronic immune system activation with ongoing cytokine signaling, infiltration of gastric mucosa by neutrophils, macrophages, lymphocytes, as well as production of antibodies and effector T-cells. Various mechanisms have been proposed in an attempt to explain the extra-intestinal manifestations of H. pylori infections. These include: molecular mimicry, endothelial cell damage, superantigens and microchimerism. I performed a systematic literature review using the keywords 'rheumatoid arthritis', 'Sjgren's syndrome', 'systemic sclerosis', 'systemic lupus erythematosus','Helicobacter pylori ' and 'pathogenesis'. A systematic literature search was carried out in MEDLINE; EMBASE; Cochrane Library and ACR/EULAR meeting abstracts. In systemic rheumatic diseases H. pylori infection prevalence alone should not be expected to provide sufficient evidence for or against a pathologic role in the disease. In this article Ⅰ review studies examining the potential involvement of H. pylori infection in autoimmune systemic rheumatic diseases. Further studies of the immunological response to H. pylori and its role in the pathogenesis of systemic rheumatic diseases are warranted. | Mislav Radic | 2014 | World Journal of Gastroenterology2014，20，36： | 9 |
| 2 | Traditional Chinese medicine “Qing Yi Tang” alleviates oxygen free radical injury in acute necrotizing pancreatitis显示文摘TraditionalChinesemedicine“QingYiTang”aleviatesoxygenfreeradicalinjuryinacutenecrotizingpancreatitisLIZhanLiang1,WUChengTan... | LI ZhanLiang1, WU ChengTang2, LU LianRong, ZHU XiaoFeng and XIONG DeXinKeywords pancreatitis/therapy Qing Yi Tang free radicals superoxide dismutase/analysis malonyldiadehyde/analysis | 1998 | World Journal of Gastroenterology1998，4，4： | 8 |
| 3 | Superior Vena Cava Resection for Lung and Mediastinal Malignancies: A Single-Center Experience With 70 Cases显示文摘 | Lorenzo Spaggiari Francesco Leo Giulia Veronesi Piergiorgio Solli Domenico Galetta Brunilda Tatani Francesco Petrella Davide Radice | 2007 | The Annals of Thoracic Surgery2007，，1： | 3 |
| 4 | Advantages and disadvantages of hysterosonosalpingography in the assessment of the reproductive status of uterine cavity and fallopian tubes显示文摘 | Radic V Canic T Valetic J | 2005 | European Journal of Radiology2005，53，2： | 1 |
| 5 | Developmental Defects in Mouse Embryos Lacking N-Cadherin显示文摘 | Glenn L. Radice Helen Rayburn Hiroaki Matsunami Karen A. Knudsen Masatoshi Takeichi Richard O. Hynes | 1997 | Developmental Biology1997，，1： | 1 |
| 6 | Drug-induced vasculitis: a clinical and pathological review显示文摘 | Radic M Kaliterna DM Radic J | 2012 | Netherlands Journal of Medicine2012，70，1： | 1 |
| 7 | Third-generation cephalosporin resistance in shigella sonnie显示文摘 | Radice M Gonzalez C Power P | 2001 | Argentina Emerg Infect Dis2001，7，： | 1 |
| 8 | Radiofrequency catheter ab-lation of the bundle branch reentrant ventricular tachycardia显示文摘 | Radic B Vukosavic D | 2001 | Acta Med Austriaca2001，28，1： | 1 |
| 9 | Analysis of staycable vibrations at the Franjo Tudman Bridge in Dubrovnik显示文摘 | HRELIJA G RADIC J SAVOR Z | 2009 | Gradevinar2009，61，9： | 1 |
| 10 | Protective role of thiolantaining agents显示文摘 | RobertoF1 Ceconlc Uureuos Oxygen free radicals and myocardial damage | 1991 | Amer J Med1991，91，： | 1 |
| 11 | Advantages and disadvantages of hysterosalpingography in the assessment of the reproductive status of uterine cavity and fallopian tubes显示文摘 | Radic V Canic T Valetic J | 2005 | Eur J Radiol2005，53，2： | 1 |
| 12 | Measurement of hydroxyl radical formation from ozone and in blood from premature babies using improved HPLC methodology显示文摘 | Kaur H Halliwell B Armatic hydroxylation of phenylalanine as an assay for hydroxyl radical | 1994 | Anal Biochem1994，220，1： | 1 |
| 13 | Analog-to-digital converter for input voltage measurements in low-power digitally controlled switch- mode power supply converters 显示文摘 | RADIC A AHSANUZZAMAN S PARAYANDEH A | 2011 | Power Electronics and Applications2011，13，2： | 1 |
| 14 | First class a carbapenemase isolated from enterobacteriaceae in Argentina 显示文摘 | Radice M Power P Gutkind G | 2004 | Antimicrob Agents Chemother2004，48，3： | 1 |
| 15 | 130- versus 135-degreesliding hip screws and failure in pertrochanteric hip fractures显示文摘 | Radic R Yates PJ Lim TS | 2014 | ANZ J Surg2014，19，25： | 1 |
| 16 | Benefits of laparoseopic-assisted eolectomy for colon polyps : a case-matched series 显示文摘 | Young-Fadok TM Radice E Nelson H | 2000 | Mayo Olin Proc2000，75，4： | 1 |
| 17 | Anti-Clq autoantibodies in lupus nephritis:prevalence and clinical significance显示文摘 | Sinico R A Radice A Ikehata M | 2005 | Ann N Y Acad Sci2005，1050，： | 1 |
| 18 | Glycopeptide resistance determinants from the teicoplanin producer Actinoplanes teichomyceticus显示文摘 | Sefina S Radice F Maffioli S | | 0，，01： | 1 |
| 19 | Tetramycin B, a new polyene macrolide antibiotioc 显示文摘 | Radics L Incze M | 1982 | Tetrahedron1982，38，1： | 1 |
| 20 | The role of cryptococcal antigen assay in diagnosis and monitoring of cryptococcal meningi- tis显示文摘 | Antinori S Radice A Galimberti L et ol | 2005 | J Clin Microbiol2005，43，11： | 1 |
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