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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | 查看详情显示文摘 | Skrobot F C Rosa L V M arques P A | | 0，，： | 1 |
| 3 | Wind models for simulation of power fluctuations from wind farms 显示文摘 | SRENSEN P HANSEN A D ROSAS P A C | 2002 | Journal of Wind Engineering and Industrial Aerodynamics2002，90，12： | 1 |
| 4 | A Competitive Mean-squared Error Approach to Beamforming显示文摘 | Eldar Y C Nehorai A La Rosa P S | 2007 | IEEE Trans on Signal Processing2007，55，11： | 1 |
| 5 | A competitive mean squared error approach to beamforming 显示文摘 | Eldar Y C Nehorai A La Rosa P S | 2007 | IEEE Transac- tions on Signal Processing2007，55，11： | 1 |
| 6 | Bioactive peptides in amaranth (Amaranthus hypochondriacus) seed显示文摘 | Silva-Sa'nchez C de la Rosa A P León-Galván M F | 2008 | J Agric Food Chem2008，56，4： | 1 |
| 7 | A competitive mean-squared error approach to beamforming 显示文摘 | Eldar Y C Nehorai A Rosa L P S | 2007 | Signal Processing IEEE Transactions2007，55，11： | 1 |
| 8 | Neridronate improves bone mineral density and reduces back pain in β-thalassaemia patients with osteoporosis:results from a phase 2,randomized,parallel-arm,open-label study显示文摘 | Forni GL Perrotta S Giusti A Quarta G Pitrolo L Cappellini MD D'Ascola DG Borgna Pignatti C Rigano P Filosa A Iolascon G Nobili B Baldini M Rosa A Pinto V Palummeri E | | 0，，： | 1 |
| 9 | Wind models for simulation of power fluctuations from wind farms 显示文摘 | Sorensen P Hansen A D Rosas P A C | 2002 | Journal of Wind Engineering and Industrial Aerodynamics2002，90，1215： | 1 |
| 10 | Oxidative leaching process with cupric ion in hydrochloric acid media for recovery of Pd and Rh from spent catalytic converters 显示文摘 | Nogueira C A Paiva A P Oliveira P C Costa M C Rosa da Costa A M | 2014 | Journal of Hazardous Materials2014，278，15： | 1 |
| 11 | Wind modelsfor simulation of power fluctuations from wind farms显示文摘 | Sorensen P Hansen A D Rosas P A C | 2002 | Journal of Wind Engineering and Industrial Aerodynamics2002，90，12： | 1 |
| 12 | Low temperature synthesis and structural characterization of nanocrystalline YAG prepared by a modified sol-gel method显示文摘 | Rosa E D Diaz-Torres L A Salas P Arredondo A Montoya J A Angeles C Rodríguez R A | | 0，，12： | 1 |
| 13 | Optical fiber probes for fluorescence based oxygen sensing显示文摘 | Jorge P A S Caldas P Rosa C C | 2004 | Sensors and Actuators B2004，103，12： | 1 |
| 14 | Elevated glucose changes the expression of ionotropic glutamate receptors subunits and impairs calcium homeostasis in retinal neural cells显示文摘 | Santiago A R Rosa S C Santos P F | 2006 | Invest Ophthalmol Vis Sci2006，47，9： | 1 |
| 15 | Life Cycle assessment of energy and environmental implications of the implementation of conservative technologies in school building in Mendoza-Argentina显示文摘 | Arena A P de Rosa C | 2003 | Building and Environment2003，38，3： | 1 |
| 16 | Hepatitis C virus polyprotein vaccine for- mulations capable of inducing broad antibody and cellularimmune responses显示文摘 | Vajdy M Selby M Medina-Selby A Coit D Hall J Tandeske L Chien D Hu C Rosa D Singh M Kazzaz J Nguyen S Coates S Ng P Abrignani S Lin YL Houghton M O'Hagan DT | 2006 | J Gen Virol2006，87，8： | 1 |
| 17 | Esthetic treatment of gingival melanin hyperpigmentation with Er: YAG laser: short-term clinical observations and patient follow-up 显示文摘 | Rosa D S Aranha A C Eduardo C P | 2007 | J Periodontol2007，78，10： | 1 |
| 18 | An innovative electromagnetic compressive split Hopkinson bar显示文摘 | Silva C M A Rosa P A R Martins P A F | 2009 | Int J Mech Mater Des2009，5，： | 1 |
| 19 | 查看详情显示文摘 | Abreu A.R Costa I Rosa C Ferreira L.M Lourenco A Santos E P | | 0，，： | 1 |
| 20 | Testing a Fluorinated Com- pound as a Protective Material for Calcarenite 显示文摘 | Rizzarelli P Rosa C L Torrisi A | 2001 | Journal of Cultural Heritage2001，，2： | 1 |
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