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| 1 | Antibacterial approaches in tissue engineering using metal ions and nanoparticles:From mechanisms to applications显示文摘Bacterial infection of implanted scaffolds may have fatal consequences and,in combination with the emergence of multidrug bacterial resistance,the development of advanced antibacterial biomaterials and constructs is of great interest.Since decades ago,metals and their ions had been used to minimize bacterial infection risk and,more recently,metal-based nanomaterials,with improved antimicrobial properties,have been advocated as a novel and tunable alternative.A comprehensive review is provided on how metal ions and ion nanoparticles have the potential to decrease or eliminate unwanted bacteria.Antibacterial mechanisms such as oxidative stress induction,ion release and disruption of biomolecules are currently well accepted.However,the exact antimicrobial mechanisms of the discussed metal compounds remain poorly understood.The combination of different metal ions and surface decorations of nanoparticles will lead to synergistic effects and improved microbial killing,and allow to mitigate potential side effects to the host.Starting with a general overview of antibacterial mechanisms,we subsequently focus on specific metal ions such as silver,zinc,copper,iron and gold,and outline their distinct modes of action.Finally,we discuss the use of these metal ions and nanoparticles in tissue engineering to prevent implant failure. | Maria Godoy-Gallardo Ulrich Eckhard Luis M.Delgado Yolanda J.D.de Roo Puente Mireia Hoyos-Nogués F.Javier Gil Roman A.Perez | 2021 | Bioactive Materials2021，6，12： | 14 |
| 2 | Productivity changes in Swedish Pharmacies 1980- 1989: A Non- parametric Malmquist approach 显示文摘 | Fare R Grosskop{ S Lindgren B Roos P | 1992 | Journal of Productivity Analysis1992，，3： | 1 |
| 3 | Elective nephron sparing surgery for renal cell carcinoma larger than 4 cm显示文摘 | Pahernik S Roos F RShrig B | 2008 | J Urol2008，179，1： | 1 |
| 4 | Apoptosis inmalignant glioma cells triggered by the temozolomide-inducedDNA lesion O6-methylguanine显示文摘 | Roos W P Batista LFZ Naumann S | 2007 | Oncogene2007，26，： | 1 |
| 5 | Nuclear-encoded, plastid-targeted genes suggest a single common origin for apicornplexan and dinoflagellate plastids显示文摘 | Fast N M Kissinger J C Roos D S | 2001 | Mol Bioi Evol2001，18，3： | 1 |
| 6 | Transcriptome of axenic liver stages of PIasmodium yoelii 显示文摘 | WANG Q BROWN S ROOS D S | 2004 | Mol Biochem Parasitol2004，137，1： | 1 |
| 7 | Progression of brain atrophy and cognitive decline in diabetes mellitus: a 3-year follow-up显示文摘 | Van Elderen S G De Roos A De Craen a J | 2010 | Neurology2010，75，11： | 1 |
| 8 | Factors affecting oocyte quality and quantity in commercial application of embryo technologies in the cattle breeding industry显示文摘 | MERTON J S DE ROOS A P W MULLAART E | | 0，，02： | 1 |
| 9 | Productivity Changes in Swedish Pharmacies 1980-1989:a Non-parametric Malmquist Approach显示文摘 | Fare R Gross kopf S Lindgren B Roos P | 1992 | Journal of Productivity Analysis1992，，3： | 1 |
| 10 | Brca2/Xrcc2dependent H R, but not NHEJ, is required for protectionagainst O6-methylguanine triggered apoptosis, DSBs andchromosomal aberrations by a process leading to SCEs 显示文摘 | Roos W P Nikolova T Quiros S | 2009 | DNARepair (Amst)2009，8，： | 1 |
| 11 | Strong association of de novo copy number mutations with sporadic schizophrenia显示文摘 | Xu B Roos JL Levy S | | 0，，7： | 1 |
| 12 | Factors affecting oocyte quality in commercial application of embryo technologies in the cattle breeding industry显示文摘 | Merton J S de Roos A P W Mullart E | 2003 | Theriogenology2003，59，： | 1 |
| 13 | Small renal tumors:correlation of clinical and pathological features with tumorsize显示文摘 | Pahernik S Ziegler S Roos F | 2007 | J Urol2007，178，2： | 1 |
| 14 | A highly viru- lent pathogen, Aeromonas hydrophila, from the freshwater crayfish Pacifastacus leniusculus 显示文摘 | Jiravanichpaisal P Roos S Edsman L | 2009 | Journal of Invertebrate Pathology2009，101，1： | 1 |
| 15 | Broad and complex anti-fungal activity among environmental isolates of lactic acid bacte显示文摘 | Magnusson J Strom K Roos S | 2003 | FEMS Microbiology Letters2003，219，1： | 1 |
| 16 | Thyroid function is as - so-ciated with components of the metabolic syndrome in euthyroidsubjects显示文摘 | Roos A Bakker S J Links TP | 2007 | J Clin Endocr Metab2007，92，2： | 1 |
| 17 | Brca2/Xrcc2 dependent HR, but not NHE], is required /or protection against 0(6)- methylguanine triggered apoptosis, DSBs and chromosomal ab- errations by a process leading to SCEs显示文摘 | Roos WP Nikolova T Quiros S | 2009 | DNA Repair2009，8，1： | 1 |
| 18 | Recent advances in treatment strategies for atopic dermatitis显示文摘 | Roos TC Gever S Roos S | 2004 | Drugs2004，64，23： | 1 |
| 19 | A high-molecular-mass cell-surface protein from Lactobacillus reuteri 1063 adheres to mucus components显示文摘 | ROOS S JONSSON H | 2002 | Microbiology2002，148，： | 1 |
| 20 | Addition of mucin to the growth medium triggers mucus-binding activity in different strains of Lactobacillus reuteri in vitro 显示文摘 | JONSSON H STROM E ROOS S | 2001 | FEMS Microbiology Letters2001，204，1： | 1 |
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