|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Altered blood-brain barrier permeability in rats with prehepatic portal hypertension turns to normal when portal pressure is lowered显示文摘AIM: To study the blood-brain barrier integrity in prehe-patic portal hypertensive rats induced by partial portal vein ligation, at 14 and 40 d after ligation when portal pressure is spontaneously normalized. METHODS: Adult male Wistar rats were divided into four groups: GroupⅠ: Sham14d, sham operated; GroupⅡ: PH14d, portal vein stenosis; (both groups were used 14 days after surgery); GroupⅢ: Sham40d, Sham operated and GroupⅣ: PH40d Portal vein stenosis (GroupsⅡandⅣused 40 d after surgery). Plasma ammonia, plasma and cerebrospinal fluid protein and liver enzymes concentrations were determined. Trypan and Evans blue dyes, systemically injected, were investigated in hippocampus to study blood-brain barrier integrity. Portal pressure was periodically recorded. RESULTS: Forty days after stricture, portal pressure was normalized, plasma ammonia was moderately high, and both dyes were absent in central nervous system parenchyma. All other parameters were reestablished. When portal pressure was normalized and ammonia level was lowered, but not normal, the altered integrity of blood-brain barrier becomes reestablished. CONCLUSION: The impairment of blood-brain barrier and subsequent normalization could be a mechanism involved in hepatic encephalopathy reversibility, Hemo-dynamic changes and ammonia could trigger blood-brain barrier alterations and its reestablishment. | Francisco Eizayaga Camila Scorticati Juan P Prestifilippo Salvador Romay Maria A Fernandez José L Castro Abraham Lemberg Juan C Perazzo | 2006 | World Journal of Gastroenterology2006，12，9： | 3 |
| 2 | Anti-inflammatory activity of phycocyanin extract in acetic acid-induced colitis in rats显示文摘 | Gonzalez R Rodriguez S Romay C | 1999 | Pharmacol Res1999，39，： | 1 |
| 3 | Effects of phycocyanin extract on tumor necrosis factor-alpha and nitrite levels in serum of mice treated with endotoxin显示文摘 | Romay C Delgado R Remirez D | 2001 | Arzneimittelforschung2001，51，： | 1 |
| 4 | sLea and sLex expression in colorectal cancer : implications for tumourigene-sis and disease prognosis显示文摘 | PORTELA S V MARTIN C V ROMAY L M | 2011 | Histol Histopathol2011，26，10： | 1 |
| 5 | Antioxidant and anti-inflammatory properties of C-phycocyanin from blue- green algae显示文摘 | Romay C H Armesto J Remirez D | 1998 | Inflamm Res1998，47，1： | 1 |
| 6 | C-phycocyanin:a biliprotein with antioxidant,anti-inflammatory and neuroprotective effects显示文摘 | ROMAY C GONZALEZ R LEDON N | 2003 | Current Protein and Peptide Science2003，4，3： | 1 |
| 7 | C-phycocyanin: a biliprotein with antioxidant, anti-inflammatory and neu- roprotective effects显示文摘 | Romay C Gonzalez R Ledon N | 2003 | Current Protein & Peptide Science2003，4，3： | 1 |
| 8 | C-phycocyanin: a biliprotein with antioxidant, anti-inflammatory and neuroprotective effects 显示文摘 | Romay C Delgado R Ledon N | 2003 | Curr Protein Pept Sci2003，4，： | 1 |
| 9 | Effects of phycocyanin extract on tumor necrosis factor-alpha and nitrite levels in serum of mice treated with endotoxin显示文摘 | Romay C Delgado R Remirez D | 2001 | Arzneimittelforsch2001，51，： | 1 |
| 10 | Evaluation of Europeanmaize germplasm under cold conditions 显示文摘 | Rodriguez V M Romay M C Ordas A | 2010 | Genetic Resources andCrop Evolution2010，57，3： | 1 |
| 11 | C-phycocyanin: a biliprotein with antioxidant, anti-inlammatory and neuroprotcctive effects显示文摘 | Romay C Gonzalez R Ledon N | 2003 | Current Protein and Peptide Science2003，4，3： | 1 |
| 12 | Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation 显示文摘 | Romay C Ledon N Gonzalez R | 1998 | Inflammation Res1998，47，8： | 1 |
| 13 | C-Phycocyanin: A biliprotein with Antioxidant, Anti-Inflammatory and Neuroprotective effects显示文摘 | Romay C Gonzdlez R Ledon N | 2003 | Current Protein Peptide Sci2003，4，： | 1 |
| 14 | Antioxidant and anti-inflammatory properties of C-pbycocyanin from blue-green algae显示文摘 | Romay C Armesto J Remirez D etal | 1998 | Inflamm Res1998，47，： | 1 |
| 15 | Anti-inflammatory activity of phycocyanin extract in acetic acid-induced colitis in rats显示文摘 | González R Rodríguez S Romay C Ancheta O González A Armesto J Remirez D Merino N | | 0，，01： | 1 |
| 16 | C-phycocyanin:a biliprotein with antioxidant,anti-inflammatory and neuroprotective effects显示文摘 | ROMAY C H GONZALEN R LEDON N | 2003 | Curr Protein Pept Sci2003，4，3： | 1 |
| 17 | Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation显示文摘 | Romay C Ledon N Gonzalez R | 1998 | Inflamm Res1998，47，： | 1 |
| 18 | Protective effects of C-phycocyanin against kainic acid-induced neuronal damage in rat hippocampus显示文摘 | Rimbau V Camins A Romay C | 1999 | Neuro-Science Letters1999，276，： | 1 |
| 19 | Effects of phycocyanin extract on tumor necrosis factor-alpha and nitrite levels in serum of mice treated with endotoxin显示文摘 | Romay C Delgado R Remirez D | 2001 | Rzneimittelforschung2001，51，： | 1 |
| 20 | C-Phycccyanin:A biliprotein with antioxidant, anti-inflammatory and neuroprotective effects 显示文摘 | ROMAY C GONZDLEZ R LED6N N | 2003 | Current Protein Peptide Sci2003，4，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员