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| 1 | 高校图书馆的工作性质正在变化显示文摘对1973年至1998年间在College&Researeh Libraries News上发布的220价招聘广告所作的内容分析表明,到1998年时,所有高校图书馆职位在日常工作中都要用到计算机技术,教学已经成为参考工作不可分割的一部分,行为技能、尤其是口头和书面交流的技能已成为新的职业要求。作为高校图书馆员所需的专业学位,由美国图书馆协会认可(ALA—accredited)的图书馆学情报学硕士仍被广泛接受。 | BeverlyP.Lynch Kimberley Robles Smith 苏扬 | 2003 | 大学图书馆学报2003，21，1： | 24 |
| 2 | Copper hydrometallurgy—current status, preliminary economics, future direction and positioning versus smelting显示文摘The heap leaching of oxide copper ores with copper cathode recovery by solvent extraction and electro-winning is now well established as a low-cost method of copper recovery. This technology has recently been applied successfully to mixed oxide and chalcocite ores, notably in Chile at Cerro Colorado, Quebrada Blanca and Zaldivar. Currently, there are significant development efforts underway to try to extend heap leaching to chalcopyrite ores. The success of heap leaching/SX/EW has also led to a revival in the development of hydrometallurgical processes to recover copper from chalcopyrite and other copper concentrates. The current status of copper hydrometallurgy is reviewed and the most commercially attractive potential applications are explored. The advantages and disadvantages of the hydrometallurgical treatment of chalcopyrite concentrates and its preliminary economics are compared with those for the current best practices in copper smelting and refining. | J. Peacey GUO Xian-jian E. Robles | 2004 | 中国有色金属学会会刊:英文版2004，14，3： | 19 |
| 3 | Assessment of drug-induced hepatotoxicity in clinical practice: A challenge for gastroenterologists显示文摘Currently, pharmaceutical preparations are serious contributors to liver disease; hepatotoxicity ranking as the most frequent cause for acute liver failure and post-commercialization regulatory decisions. The diagnosis of hepatotoxicity remains a difficult task because of the lack of reliable markers for use in general clinical practice. To incriminate any given drug in an episode of liver dysfunction is a step-by-step process that requires a high degree of suspicion, compatible chronology, awareness of the drug’s hepatotoxic potential, the exclusion of alternative causes of liver damage and the ability to detect the presence of subtle data that favors a toxic etiology. This process is time-consuming and the final result is frequently inaccurate. Diagnostic algorithms may add consistency to the diagnostic process by translating the suspicion into a quantitative score. Such scales are useful since they provide a framework that emphasizes the features that merit attention in cases of suspected hepatic adverse reaction as well. Current efforts in collecting bona fide cases of drug-induced hepatotoxicity will make refinements of existing scales feasible. It is now relatively easy to accommodate relevant data within the scoring system and to delete low-impact items. Efforts should also be directed toward the development of an abridged instrument for use in evaluating suspected drug-induced hepatotoxicity at the very beginning of the diagnosis and treatment process when clinical decisions need to be made. The instrument chosen would enable a confident diagnosis to be made on admission of the patient and treatment to be fine-tuned as further information is collected. | Raúl J Andrade Mercedes Robles Alejandra Fernández-Castaer Susana López-Ortega M Carmen López-Vega M Isabel Lucena | 2007 | World Journal of Gastroenterology2007，13，3： | 18 |
| 4 | Liver transplantation for hilar cholangiocarcinoma显示文摘The most appropriate treatment for Klatskin tumor(KT)with a curative intention is multimodal therapy based on achieving resection with tumour-free margins(R0resections)combined with other types of neoadjuvant or adjuvant treatment(the most important factor affecting KT survival is the possibility of R0 resections,achieving 5-year survival rate of 40%-50%).Thirty to forty percent of patients with KT are inoperable and present a 5-year survival rate of 0%.In irresectable non-disseminated KT patients,using liver transplantation without neoadjuvant treatment,the 5-year survival rate increase to 38%,reaching 50%survival in early stage.In selected cases,with liver transplantation and neoadjuvant treatment(chemotherapy and radiotherapy),the actuarial survival rate is 65%at 5 years and 59%at 10 years.In conclusion,correct staging,neoadjuvant treatment,living donor and priority on the liver transplant waiting list may lead to improved results. | Ricardo Robles Francisco Sánchez-Bueno Pablo Ramírez Roberto Brusadin Pascual Parrilla | 2013 | World Journal of Gastroenterology2013，19，48： | 17 |
| 5 | Spanish E-government and the Third Digital Divide: A Sociological View显示文摘 | Jose Manuel Robles Cristobal Torres-Albero Stefano de Marco | 2011 | Journal of US-China Public Administration2011，8，4： | 9 |
| 6 | Post-traumatic hepatic artery pseudoaneurysm treated with endovascular embolization and thrombin injection显示文摘Post-traumatic hepatic artery pseudoaneurysm is unc-ommon,appearing in approximately 1%of hepatic trauma cases.Most are extrahepatic(80%)and have a late onset.Although they are usually asymptomatic, they should always be treated becasue of the high risk of complications,especially breakage.Currently the treatment of choice is endovascular embolization with coils or the exclusion of the pseudoaneurysm using other intravascular devices.Recently there have been accounts of a treatment that combines embolization with coils and image-guided percutaneous human thrombin injection.We present a case of post-traumatichepatic artery pseudoaneurysm that was successfully treated using this combined technique. | Lloret Esta Francisco López Conesa Asunción Capel Alemán Antonio Robles Campos Ricardo Reus Pintado Manuel Marín Hernández Caridad | 2010 | World Journal of Hepatology2010，2，2： | 9 |
| 7 | Diabetic gastroenteropathy:An underdiagnosed complication显示文摘This article is an extensive review that provides an update on the pathophysiology,symptoms,diagnosis,and treatment of diabetic gastroenteropathy.There is no reported prevalence,but it has been described that patients with type 1 diabetes have a cumulative incidence at 10 years of 5.2%,and type 2 patients,1%.Also,in the group of type 1 diabetes,it has been observed that women are more likely to present this condition(5.8%vs 3.5%).Many factors are associate with its development(e.g.,hyperglycemia,vagal dysfunction,loss of expression of neural nitric oxide synthase in the myenteric plexus,alterations in the Cajal interstitial cell network,and oxidative stress).Gastrointestinal discomfort could be perceived 70% higher in diabetic patients,describing that 25%of diabetic patients experience gastrointestinal symptoms.Diabetic enteropathy could affect any portion of the gastrointestinal tract,but esophageal alterations were described in more than 60% of diabetic patients,also 60% of them present constipation,and 20%,diarrhea.Gastric emptying scintigraphy is useful to evaluate gastroparesis,therefore,gastric retention of more than 60%at 2 h has a sensitivity of 100% and specificity of 20% for diagnosis;however,other studies such as breath tests,with a sensitivity of 89% and a specificity of 80%,or the endoscopic capsule contribute to the diagnosis.There is no cure;however,management must be multidisciplinary,focused on slowing the progression of diabetic gastroenteropathy,reducing symptoms,and restoring function;that includes nutritional recommendation,maintain glucose levels kept below 180 mg/dL,use of prokinetics,anti-emetics;nowadays,it has been special interest in surgical treatment,such as pyloroplasty,also gastric electrical stimulation appears to be another alternative. | Marcio JoséConcepción Zavaleta Jhean Gabriel Gonzáles Yovera Diego Martín Moreno Marreros Luciana del Pilar Rafael Robles Kely Roxana Palomino Taype Karen Nohelly Soto Gálvez Luis Fernando Arriola Torres Julia Cristina Coronado Arroyo Luis Alberto Concepción Urteaga | 2021 | World Journal of Diabetes2021，12，6： | 4 |
| 8 | 超细干法脱硫灰在水泥混凝土中的应用研究显示文摘研究了循环流化床锅炉配套干法脱硫装置再脱硫所产生的脱硫灰作为水泥掺合料的可行性。评估了干式和湿式球磨对脱硫灰的细度、成分和活性的影响。结果表明:湿磨对脱硫灰磨细更有效,磨细90 min后中位粒径约3μm,磨细对脱硫灰的成分影响不大;磨细可有效提高脱硫灰的活性,并实现超细脱硫灰替代20%波特兰水泥的胶砂早期强度与控制配方相当,28 d后胶砂强度优于控制配方,水泥混凝土在7 d后抗压强度高于控制配方,28 d抗压强度达到控制配方的120%;磨细对胶砂尺寸稳定性影响较小。 | 苏清发 陈永瑞 Bob Jewell Tom Robl 陈宏 赖毅强 吴慕正 陈进生 | 2019 | 新型建筑材料2019，46，12： | 4 |
| 9 | Treatment with dimethyl fumarate ameliorates liver ischemia/reperfusion injury显示文摘AIM To investigate the hypothesis that treatment with dimethyl fumarate(D MF) mayame liorate liver ischemia/reperfusion injury(I/RI).METHODS Rats were divided into 3 groups: sham, control(CTL), and DMF. DMF(25 mg/kg, twice/d) was orally administered for 2 d before the procedure. The CTL and DMF rats were subjected to ischemia for 1 h and reperfusion for 2 h. The serum alanine aminotransferase(ALT) and malondialdehyde(MDA) levels, adenosine triphosphate(ATP), NO × metabolites, anti-oxidant enzyme expression level, antiinflammatory effect, and anti-apoptotic effect were determined.RESULTS Histological tissue damage was significantly reduced in the DMF group(Suzuki scores: sham: 0 ± 0; CTL: 9.3± 0.5; DMF: 2.5 ± 1.2; sham vs CTL, P < 0.0001; CTL vs DMF, P < 0.0001). This effect was associated with significantly lower serum ALT(DMF 5026 ± 2305 U/L vs CTL 10592 ± 1152 U/L, P = 0.04) and MDA(DMF 18.2 ± 1.4 μmol/L vs CTL 26.0 ± 1.0 μmol/L, P = 0.0009). DMF effectively improved the ATP content(DMF 20.3 ± 0.4 nmol/mg vs CTL 18.3 ± 0.6 nmol/mg, P = 0.02), myeloperoxidase activity(DMF 7.8 ± 0.4 m U/m L vs CTL 6.0 ± 0.5 m U/m L, P = 0.01) and level of endothelial nitric oxide synthase expression(DMF 0.38 ± 0.05-fold vs 0.17 ± 0.06-fold, P = 0.02). The higher expression levels of anti-oxidant enzymes(catalase and glutamatecysteine ligase modifier subunit and lower levels of key inflammatory mediators(nuclear factor-kappa B and cyclooxygenase-2 were confirmed in the DMF group.CONCLUSION DMF improved the liver function and the anti-oxidant and inflammation status following I/RI. Treatment with DMF could be a promising strategy in patients with liver I/RI. | Chie Takasu Nosratola D Vaziri Shiri Li Lourdes Robles Kelly Vo Mizuki Takasu Christine Pham Seyed H Farzaneh Mitsuo Shimada Michael J Stamos Hirohito Ichii | 2017 | World Journal of Gastroenterology2017，23，25： | 3 |
| 10 | Cyber Portfolio: The Innovative Menu for 21st Century Technology显示文摘 | Ava Clare Marie O. Robles | 2012 | Psychology Research2012，2，3： | 2 |
| 11 | High-throughput genetic mapping in Arabidopsos thaliana显示文摘 | Ponce M R Robles P Micol J L | 1999 | Mol Gen Genet1999，261，： | 2 |
| 12 | Innovative active modified atmosphere packaging improves overall quality of fresh-cut red chard baby leaves显示文摘 | Alejandro Tomás-Callejas María Boluda Pedro Antonio Robles Francisco Artés Francisco Artés-Hernández | 2011 | LWT - Food Science and Technology2011，，6： | 2 |
| 13 | 矿化剂硫酸钙和氟化钙作用下硅酸三钙的合成(英文)显示文摘硅酸三钙(C3S)是硅酸盐水泥和阿利特硫铝酸盐水泥熟料中重要的矿物之一。为研究C3S的特性和性能,使用CaSO4和CaF2作为矿化剂,分别在1 350、1 400和1 450℃合成了高纯度的C3S。1 350℃得到的C3S纯度高于95%,而在1 400和1 450℃合成的C3S纯度高于97%。检测结果显示3个不同温度下合成的C3S的游离氧化钙含量均小于1%。样品的化学成分分析表明,1 400和1 450℃合成的C3S中仅有痕量的SO3存在,合成过程中几乎所有的CaSO4均分解为CaO,并且与部分SiO2形成了C3S。对所有样品的X射线衍射分析结果显示,合成的C3S为M1与(或)M3型。扫描电子显微镜分析结果显示,不同温度下合成的C3S的微结构有所不同。通过差热分析对矿化剂作用下的C3S合成过程进行了分析,结果表明该合成方法与通常的C2S和CaO通过固相反应合成C3S之间存在显著差异,是一个两步合成过程。 | 周勇敏 Tom ROBL Kevin HENKE | 2014 | 硅酸盐学报2014，42，5： | 2 |
| 14 | Unveiling Plant mTERF Functions显示文摘Chloroplasts and mitochondria genomes contain a few dozen genes required for gene expression,photosynthesis,and the electron transport chain.However,proteomic and bioinformatic studies suggest that approximately 2000 and 2600 proteins are located in plant mitochondria and chloroplasts,respectively;most of them are encoded by nuclear genes,synthesized in the cytoplasm,and targeted to organelles.Despite the simplicity of organelle genomes,their transcriptional regulation is complex and can only be partially explained by currently known transcriptional machinery components,suggesting that additional unidentified regulatory factors exist (Liere et al.,2011). | Pedro Robles Jose Luis Micol Victor Quesada | 2012 | Molecular Plant2012，5，2： | 2 |
| 15 | Clinical characteristics and type of antithrombotic treatment in a Spanish cohort of elderly patients with atrial fibrillation according to dependency, frailty and cognitive impairment显示文摘根据相关性,脆弱和认知缺陷与 atrial 纤维性颤动(AF ) 考虑老病人的临床的侧面和管理的 BackgroundAvailable 数据是少见的。学习的目的是根据相关性分析 biodemographic 数据,临床的侧面和 antithrombotic 治疗,吗在patients.MethodsCross部分的老 AF 和学习在 75 年与 3 个月在 Spain.ResultsA 在内部药部门出席了的口头的抗凝剂对待的连续 AF 病人执行了的多中心的脆弱和认知缺陷 837 总计病人( 83.0 ???????????????????吗???????????????????￡?? | Jose Maria Mostaza Manuel Jesús Romero Jiménez Fernando José Ruiz Laiglesia José Antonio Díaz Peromingo Manuel Beltrán Robles Ernesto Guevara Sierra Ana Santander Bilbao Carmen Suárez | 2018 | Journal of Geriatric Cardiology2018，15，4： | 2 |
| 16 | Preliminary studies on the cryopreservation of gilthead seabream (Sparusaurata) embryos显示文摘 | Cabrita E Robles V Wallace J C | 2006 | Aquaculture2006，25，24： | 1 |
| 17 | Ni^ittimeblood pressure fall in renal disease patients显示文摘 | Robles NR Cancho B Ruiz-Calero R | 2003 | RenFail2003，25，： | 1 |
| 18 | The SEP4 gene of Arabidop- sis thaliana functions in floral organ and meristem identity显示文摘 | Ditta G Pinyopich A Robles P | 2004 | Curr Biol2004，14，21： | 1 |
| 19 | Night- time blood pressure fall in renal disease patients显示文摘 | Robles NR Cancho B Ruiz-Calero R | 2003 | Ren Fail2003，25，： | 1 |
| 20 | Genetic variation in mi- croRNA networks: the imp显示文摘 | Ryan BM Robles AI Harris CC | 2010 | Nat Rev Cancer2010，10，： | 1 |
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