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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Effect of the preparation method on the catalytic activity of La1_xCaxFeO3 perovskite-type oxides显示文摘 | Pecchi G Reyes P Zamora R Campos C | 2008 | Catalysis Today2008，，： | 1 |
| 3 | Long-term,short-term and renegotiation:On the value of commitment in contracting显示文摘 | Rey P Salanie B | 1990 | Econometrica1990，58，3： | 1 |
| 4 | Resuhs of the GYNECO 02 study, an FNCLCC phase Ⅲ trial comparing hysterec- tomy with no hysterectomy in patients with a(clinical and radiologieal) complete response after chemoradiation therapy for stage Ⅰ B2 or Ⅱ cervical cancer显示文摘 | Morice P Rouanet P Rey A | 2012 | Oncologist2012，17，1： | 1 |
| 5 | The soil and water assessment tools: historical development, ap- plications, and future research directions显示文摘 | Gassman P W Reyes M R Green C H | 2007 | Transac- tions of the ASABE2007，50，4： | 1 |
| 6 | Orotidylate-metabolizing enzymes of the human malarial parasite,Plasmodium falciparum,differ from host cell enzymes显示文摘 | Rathod P K Reyes P | | 0，，05： | 1 |
| 7 | Simultaneous application of transglutaminase and high pressure to improve functional properties of chicken meat gels显示文摘 | TRESPALACION P REYES P | 2007 | Food Chemistry2007，100，1： | 1 |
| 8 | Isolation and characterization of PRA1,a trypsin -like protease from the biocontrol agent Trichoderma har-zianum CECT 2413 displaying nematicidal activity显示文摘 | SUAREZ B REY M CASTILLO P | 2004 | Appl Microbiol Bio-technol2004，，： | 1 |
| 9 | Cal- culating structures and free energies of complex molecules: combining molecular mechanics and con- tinuum models显示文摘 | KOLLMAN P A MASSOVA I REYES C | 2000 | Acc Chem Res2000，33，12： | 1 |
| 10 | Pilot clinical study of an endoscopic, removable duodenal-jejunal bypass liner for the treat- ment of type 2 diabetes 显示文摘 | Rodriguez L Reyes E Fagalde P | 2009 | Diabetes Technol Ther2009，11，11： | 1 |
| 11 | Direct asymmetric intermolecular aldol reactions catalyzed by amino acids and small peptides显示文摘 | Cordova A Zou W Dziedzic P Ibrahem I Reyes E Xu Y | 2006 | Chem Eur J2006，12，： | 1 |
| 12 | Measles in Spain:its move into the adult population显示文摘 | Pena Rey Lorenzo I Santa Olalla Peralta P Amela Heras C | 2004 | Aten Primaria2004，33，4： | 1 |
| 13 | The soil and water assessment tool: historical development, applications, and future research directions 显示文摘 | Gassman P W Reyes M R Green C H | 2007 | American Society of Agriculture and Biology Engineers2007，50，4： | 1 |
| 14 | Catalytic combustion of methane on Pd-Cu/SiO2 catalysts显示文摘 | REYES P FIGUEROA A PECCHI G | 2000 | Catal Today2000，62，23： | 1 |
| 15 | Dalteparin for the prevention of recurrence of placental-mediated complications of pregnancy in women without thrombophilia:a pilot randomized controlled trial显示文摘 | Rey E Garneau P David M Gauthier R Leduc L Michon N | 2009 | J Thromb Haemost2009，7，1： | 1 |
| 16 | Nipple-sparing mastectomy: rick of nipple-areolar recurrence in a series of 576 ease 显示文摘 | Petit JY Veronesi U Rey P | 2009 | Brest Cancer Res Treat2009，114，1： | 1 |
| 17 | Enzymes of pu-rine and pyrimidine metabolism from the human malaria para-site, Plasmodium falciparum显示文摘 | Reyes P Rathod P K Sanchez D J | | 0，，05： | 1 |
| 18 | Sequence-independent, single-primer amplification(SISPA) of complex DNA populations显示文摘 | Reyes G R Kim J P | 1991 | Mol Cell Probes1991，5，： | 1 |
| 19 | Effects of Network Eco- nomic in High-speed Rail : The Spanish Case 显示文摘 | Coto-Millan P Inglada V Rey B | 2007 | Annals of Regional Science2007，41，4： | 1 |
| 20 | Serum concentrations of leptin, adiponectin and resistin, and their relationship with cardiovascular disease in patients with end-stage renal disease 显示文摘 | DIEZ JJ IGLESIAS P FERNANDEZ- REYES M J | 2005 | Clin Endocrinol(Oxf)2005，62，2： | 1 |
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