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| 1 | Alpha-fetoprotein expression is a potential prognostic marker in hepatocellular carcinoma显示文摘AIM: To characterize the alpha-fetoprotein (AFP) positive and negative hepatocellular carcinoma (HCC) samples.METHODS: Thirty-seven paraffin-embedded human HCC samples were analyzed by immunohistochemistry for the following antigens: AFP, β-catenin, p53, CD44, MSH-2,MLH-1, and HNF-4. The tumors were divided into two groups based on the AFP expression. The immunophenotypic data and important clinical parameters were studied between the two groups.RESULTS: Twenty-one of the thirty-seven examined HCCs were AFP positive. Seven with nuclear p53 staining were AFP positive, while seven tumors with nuclear β-catenin staining were AFP negative. CD44 staining and high histological tumor grade were more frequent among the AFP-positive HCCs. The other immunophenotypical and dinical parameters did not show statistically significant difference in their distribution between the AFP positive and negative samples.CONCLUSION: AFP expression in HCC correlates with unfavorable prognostic factors, while nuclear β-catenin positivity is more common among the AFP-negative liver tumors. This observation supports the microarray data onin vivo human tumors. | Dénes Grg János Regly-Mérei Sándor Paku László Kopper Péter Nagy | 2005 | World Journal of Gastroenterology2005，11，32： | 6 |
| 2 | Acute gouty synovitis associated with 'urate milk' 显示文摘 | FAM A G REIS M D SZALAI J P | 1997 | J Rheumatol1997，24，12： | 1 |
| 3 | Total inhibin is a potential serum marker for epithelial ovarian cancer显示文摘 | Tsigkou A Marrelli D Reis FM | 2007 | J Clin Endocrinol Metab2007，92，7： | 1 |
| 4 | Photochemical behavior under UVA radiation of β-cyclodextrin included Parsol 1789 with a chemometric approach 显示文摘 | Biloti D N dos Reis M M Ferreira M M C | 1999 | Journal of Molecular Structure1999，，480481： | 1 |
| 5 | Role of potassium channels in the central nueroproteetion elicited by cerebellar stimulation in rat 显示文摘 | Golanov EV Christensen D Reis D | 1999 | Brain Res1999，842，2： | 1 |
| 6 | Vapor Bubble Departure in Forced Convection Boiling显示文摘 | Rei R Bernhard D M | 1993 | Int J Heat and Mass Transfer1993，36，： | 1 |
| 7 | Treatment of patients admitted to the hospital with congestive heart failure:Specialty-related disparities in practice patterns and outcomes显示文摘 | REIS S E HOLUBKOV R EDMUNDOWICZ D | 1997 | J Am Coll Cardiol1997，30，： | 1 |
| 8 | Hyperbaric oxygen therapy as a treatment for stage-1 avascular necrosis of the femoral head显示文摘 | Reis ND Schwartz O Militianu D | 2003 | J Bone Joint Surg Br2003，85，3： | 1 |
| 9 | Neuroprotective electrical stimulation of cerebellar fastigial nucleus attenuates expression of peri-infarction depolarizing waves(PIDs) and inhibits cortical spreading depression显示文摘 | Golanov EV Reis D | 1999 | Brain Res1999，818，2： | 1 |
| 10 | Vitamin D Status and Cardiovascular Health : a 2009 update 显示文摘 | Erin D Michos Jared P Reis Michal L Melamed | 2010 | The Open Clinical Chemistry Journal2010，3，： | 1 |
| 11 | Effect of spacing and age on nitrogen and phosphorus distribution in biomass of Eucalyptus camaldulensis,Eucalyptus pellita and Eucalyptus urophylla plantations in southeastern Brazil显示文摘 | Harrison R B Reis G G Reis M D G F | 2000 | Forest Ecology and Management2000，133，3： | 1 |
| 12 | Sulfate reduction in acidogenic phase anaerobic-digestion 显示文摘 | REIS M A M GONCALVES L M D CARRONDO M J T | 1988 | Water Science and Technology1988，20，1112： | 1 |
| 13 | Coherent control of pulsed X-ray beams显示文摘 | DeCamp M F Reis D A Bucksbaum P H | 2001 | Nature2001，413，6858： | 1 |
| 14 | Sleep characteris- tics, sleep problems, and associations to quality of life among psyehotherapists显示文摘 | SCHLARB A A REIS D SCHRODER A | 2012 | Sleep Disorders2012，，12： | 1 |
| 15 | Hyperbaric oxygen therapy as a treatment for stage-1 avascular necrosis of the femoral head 显示文摘 | Reis ND Schwartz O Militianu D | 2003 | J Bone Joint Surg Br2003，85，3： | 1 |
| 16 | Role of potassium channels in the central nueroprotection elicited by cerebellar stimulation in rat 显示文摘 | Golanov EV Christensen D Reis D | 1999 | Brain Res1999，842，2： | 1 |
| 17 | Tailored Welded Blanks-an Experimental and Numerical Study in Sheet Metal Forming on the Effect of Welding显示文摘 | Reis A Teixeira P Ferreira D J | | 0，，： | 1 |
| 18 | Hyperbaric oxygen therapy as a treatment for stage-Ⅰ avascular necrosis of the femoral head显示文摘 | Reis ND Schwartz O Militianu D | 2003 | J Bone Joint Surg Br2003，85，3： | 1 |
| 19 | Genetic pro- file of gliosarcomas显示文摘 | Reis R M Konu-Lebleblicioglu D Lopes J M | 2000 | Am J Pathol2000，156，2： | 1 |
| 20 | Hyperbaric oxygen therapy as a treatment for stage - 1 avascular neerosis of the femoral head 显示文摘 | Reis D Schuiartz O Militianu D | 2003 | J Bone Joint Surg Br2003，85，3： | 1 |
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