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| 1 | 基于AHP_熵权法的孟印缅地区洪水灾害风险评估显示文摘孟印缅三国地处亚热带与热带季风气候区,因自然条件制约,洪涝灾害频繁发生,对'孟中印缅经济走廊'建设将会带来重大影响。开展孟印缅地区的洪水风险评估可为'孟中印缅经济走廊'的建设安全提供必要的信息和科技支撑。利用1980—2016年的降水数据,结合河网、数字高程和土地利用等数据,选取雨季降雨量、暴雨天数、高程、坡度、河网密度、植被覆盖度、土壤可蚀性、人口密度、地均GDP和土地利用10个指标,采用层次分析法和AHP_熵权法对孟印缅地区的洪水灾害风险分布进行了比较研究。研究表明:孟印缅地区高风险区和较高风险区分别占总面积的1.05%和28.76%,高风险区主要分布在印度北部的恒河平原、印度东北部的阿萨姆邦、孟加拉国大部分地区和缅甸南部。受自然、人口和经济条件的制约,孟加拉国是孟印缅三国中洪水风险最高的国家,高风险区和较高风险区分别占总面积的10.61%和65.87%。层次分析法和AHP_熵权法结果间的比较表明,后者比前者识别出更大范围的洪水高风险区。本研究为中国开展周边国家自然灾害的风险评估提供了有效的方法,有助于推进国家孟中印缅经济走廊的建设。 | 刘媛媛 王绍强 王小博 江东 N H Ravindranath Atiq Rahman Nyo Mar Htwe Tartirose Vijitpan | 2020 | 地理研究2020，39，8： | 57 |
| 2 | Advances in management of type 1 diabetes mellitus显示文摘Treatment of type 1 diabetes mellitus has always posed a challenge to balance hyperglycemia control with hypoglycemia episodes. The quest for newer therapies is continuing and this review attempts to outline the recent developments. The insulin molecule itself has got moulded into different analogues by minor changes in its structure to ensure well controlled delivery, stable half-lives and lesser side effects. Insulin delivery systems have also consistently undergone advances from subcutaneous injections to continuous infusion to trials of inhalational delivery. Continuous glucose monitoring systems are also becoming more accurate and user friendly. Smartphones have also made their entry into therapy of diabetes by integrating blood glucose levels and food intake with calculated adequate insulin required. Artificial pancreas has enabled to a certain extent to close the loop between blood glucose level and insulin delivery with devices armed with meal and exercise announcements, dual hormone delivery and pramlintide infusion. Islet, pancreas-kidney and stem cells transplants are also being attempted though complete success is still a far way off. Incorporating insulin gene and secretary apparatus is another ambitious leap to achieve insulin independence though the search for the ideal vector and target cell is still continuing. Finally to stand up to the statement, prevention is better than cure, immunological methods are being investigated to be used as vaccine to prevent the onset of diabetes mellitus. | Ravindranath Aathira Vandana Jain | 2014 | World Journal of Diabetes2014，5，5： | 3 |
| 3 | Prognostic factors associated with hospital survival in comatose survivors of cardiac arrest显示文摘AIM: To identify patient, cardiac arrest and management factors associated with hospital survival in comatose survivors of cardiac arrest.METHODS: A retrospective, single centre study of comatose patients admitted to our intensive care unit(ICU) following cardiac arrest during the twenty year period between 1993 and 2012. This study was deemed by the Human Research Ethics Committee(HREC) of Monash Health to be a quality assurance exercise, and thus did not require submission to the Monash Health HREC(Research Project Application, No. 13290Q). The study population included all patients admitted to ourICU between 1993 and 2012, with a discharge diagnosis including 'cardiac arrest'. Patients were excluded if they did not have a cardiac arrest prior to ICU admission(i.e.,if their primary arrest was during their admission to ICU),or were not comatose on arrival to ICU. Our primary outcome measure was survival to hospital discharge.Secondary outcome measures were ICU and hospita length of stay(LOS), and factors associated with surviva to hospital discharge.RESULTS: Five hundred and eighty-two comatose patients were admitted to our ICU following cardiac arrest, with 35% surviving to hospital discharge. The median ICU and hospital LOS was 3 and 5 d respectively.There was no survival difference between in-hospital and out-of-hospital cardiac arrests. Males made up 62% of our cardiac arrest population, were more likely to have a shockable rhythm(56% vs 37%, P < 0.001), and were more likely to survive to hospital discharge(40%vs 28%, P = 0.006). On univariate analysis, therapeutic hypothermia, regardless of method used(e.g., rapid infusion of ice cold fluids, topical ice, 'Arctic Sun', passive rewarming, 'Bair Hugger') and location initiated(e.g.,pre-hospital, emergency department, intensive care) was associated with increased survival. There was however no difference in survival associated with target temperature,time at target temperature, location of initial cooling,method of initiating cooling, method of maintaining cooling or method of rewarming. Patients that survived were more likely to have a shockable rhythm(P < 0.001),shorter time to return of spontaneous circulation(P <0.001), receive therapeutic hypothermia(P = 0.03), be of male gender(P = 0.006) and have a lower APACHEⅡ score(P < 0.001). After multivariate analysis, only a shockable initial rhythm(OR = 6.4, 95%CI: 3.95-10.4;P < 0.01) and a shorter time to return of spontaneous circulation(OR = 0.95, 95%CI: 0.93-0.97; P < 0.01) was found to be independently associated with survival to hospital discharge.CONCLUSION: In comatose survivors of cardiac arrest, shockable rhythm and shorter time to return of spontaneous circulation were independently associated with increased survival to hospital discharge. | Kushaharan Sathianathan Ravindranath Tiruvoipati Sanjiv Vij | 2016 | World Journal of Critical Care Medicine2016，5，1： | 3 |
| 4 | Serum bicarbonate may independently predict acute kidney injury in critically ill patients:An observational study显示文摘AIM: To explore whether serum bicarbonate at admission to intensive care unit(ICU) predicted development of acute kidney injury(AKI).METHODS:We studied all patients admitted to our ICU over a 2 year period(February 2010 to 2012).The ICU has a case mix of medical and surgical patients excluding cardiac surgical,trauma and neurosurgical patients.We analysed 2035 consecutive patients admitted to ICU during the study period.Data were collected by two investigators independently and in duplicate using a standardised spread sheet to ensure accuracy.Ambiguous data were checked for accuracy where indicated.AKI was defined using the Kidney Disease Improving Global Outcomes criteria.Patients were divided into two groups;patients who developed AKI or those who did not,in order to compare the baseline characteristics,and laboratory and physiologic data of the two cohorts.Regression analysis was used to identify if serum bicarbonate on admission predicted the development of AKI.RESULTS:Of 2036 patients 152(7.5%)were excluded due to missing data.AKI developed in 43.1%of the patients.The AKI group,compared to the nonAKI group,was sicker based on their lower systolic,diastolic and mean arterial pressures and a higher acutephysiology and chronic health evaluation(APACHE)Ⅲand SAPSⅡscores.Moreover,patients who developed AKI had more co-morbidities and a higher proportion of patients who developed AKI required mechanical ventilation.The multi-regression analysis of independent variables showed that serum bicarbonate on admission(OR=0.821;95%CI:0.796-0.846;P<0.0001),APACHEⅢ(OR=1.011;95%CI:1.007-1.015;P<0.0001),age(OR=1.016;95%CI:1.008-1.024;P<0.0001)and presence of sepsis at ICU admission(OR=2.819;95%CI:2.122-23.744;P=0.004)were each significant independent predictors of AKI.The area under the ROC curve was 0.8(95%CI:0.78-0.83),thereby demonstrating that the predictive model has relatively good discriminating power for predicting AKI.CONCLUSION:Serum bicarbonate on admission may independently be used to make a diagnosis of AKI. | Anuksha Gujadhur Ravindranath Tiruvoipati Elizabeth Cole Saada Malouf Erum Sahid Ansari Kim Wong | 2015 | World Journal of Critical Care Medicine2015，4，1： | 3 |
| 5 | 中国超级杂交稻在孟印缅地区的生产潜力模拟显示文摘水稻是孟加拉国、印度和缅甸最重要的粮食作物,研究中国超级杂交稻对孟印缅地区的水稻增产潜力,对于保障孟中印缅经济走廊的粮食安全与区域可持续发展具有重要的现实意义。在全面收集孟印缅地区气候、土壤、田间管理信息和农业统计数据的基础上,结合中国籼型杂交稻F优498和丰两优4号的品种信息和区试数据,通过EPIC模型模拟了1996-2005年雨季孟印缅3国在不同情景下的超级稻生产潜力,并分析了孟印缅地区主要胁迫因子对超级稻单产潜力的影响。研究表明:(1)中国超级杂交稻在孟印缅地区2000年的灌溉和施肥水平下单产潜力为10.22 t/ha,在充分灌溉且合理施肥的水平下单产潜力为11.33 t/ha。(2)孟印缅地区雨季稻的增产空间达22771万t,水稻增产潜力最大的地区是印度的恒河平原东部、印度半岛东南沿海与缅甸的伊洛瓦底三角洲。(3)印度德干高原东北部、西南部和印度大平原西北部需要进一步完善灌溉设备以满足高产水稻用水,缅甸的中南部平原地区和印度的东北地区则需要增施氮肥以满足高产水稻用肥。 | 王小博 王绍强 陈敬华 崔惠娟 吴宜进 N H RAVINDRANATH A RAHMAN | 2018 | 地理学报2018，73，11： | 2 |
| 6 | Antieancer therapeutic potential of soy isoflavone,genistein显示文摘 | Ravindranath M H Muthugounder S Presser N | 2004 | Adv Exp Med Biol2004，546，： | 1 |
| 7 | Variation of aza- dirachtin content during growth and storage of Neem (Azadirachta indica) seeds 显示文摘 | Yakkundi S R Thejavathi R Ravindranath B | 1995 | Journal of Agricultural and Food Chemistry1995，43，： | 1 |
| 8 | Fingerprint ridgecount difference between adjacent fingertips(dR45)predicts upper-body tissue distribution:evidence for early gestational programming显示文摘 | Kahn HS Ravindranath R Valdez R | | 0，，04： | 1 |
| 9 | Anticancer therapeutic potential of soy isoflavone, genistein 显示文摘 | Ravindranath MH Muthugounder S Presser N | 2004 | Adv Exp Med Biol2004，546，2： | 1 |
| 10 | Effects of pentoxyfylline on mesenteric lymph node T-cells in a rat model of thermal injury显示文摘 | KOTADIA BK RAVINDRANATH TM CHOUDHRY MA | 2003 | Shock2003，20，6： | 1 |
| 11 | Spatiotemporal expression of ameloblastin isforms during murine tooth development显示文摘 | RAVINDRANATH RM DEVARAJAN A UCHILDA T | 2007 | J Biol Chem2007，，36： | 1 |
| 12 | Cooperative networks and competitive dynamics:A structural embeddedness perspective显示文摘 | Devi R Gnyawal Ravindranath Madhavan | 2001 | Academy of Management Review2001，26，3： | 1 |
| 13 | Assessment of sustainable non-plantation biomass re- sources potential for energy in India 显示文摘 | Ravindranath N H Somashekar H I Nagaraja M S | 2005 | Biomass and Bioenergy2005，29，3： | 1 |
| 14 | Cryosurgical ablation of liver tumors in colon cancer patients increases the serum total ganglioside level and then selectively augments antiganglioside IgM显示文摘 | Mepur H Ravindranath Thomas F Wood Daniel Soh Alexandra Gonzales Sakunthala Muthugounder Carlos Perez Donald L Morton Anton J Bilchik | 2002 | Cryobiology2002，，1： | 1 |
| 15 | M yelodysplastic syndrome in children; changing definitions from FAB 1976 to WHO 2008 classification systems显示文摘 | Ravindranath Y | 2011 | Pediatr Blood Cancer2011，57，7： | 1 |
| 16 | Two's Company, Three' s a Crown? Triads in Cooperative- Competitive Networks 显示文摘 | Madhavan Ravindranath Devi R Gnyawali Jinyu He | 2004 | Academy of Management Journal2004，47，6： | 1 |
| 17 | A simple, mild and efficient procedure for selective cleavage of pre- nyl esters using silica-supported sodium hydrogen sulphate as a heterogenous catalyst 显示文摘 | Ramesh C Mahender G Ravindranath N Biswanath D | 2003 | Tetrahedron letters2003，44，7： | 1 |
| 18 | Stem cell factor/c-kit up-regulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3-kinase/p70 S6 kinase pathway in spermatogonia显示文摘 | Feng LX Ravindranath N Dym M | 2000 | J Biol Chem2000，275，25： | 1 |
| 19 | Activation of p38 MAPK in the substantia nigra leads to nuclear translocation of NF-kappaB in MPTP-treated mice: implication in Parkinson ' s disease 显示文摘 | KARUNAKARAN S RAVINDRANATH V | 2009 | J Neurochem2009，109，6： | 1 |
| 20 | Vascular endothelail growth factor messenger ribonucleic acid expression in the primate ovary显示文摘 | Ravindranath N little-lhrig L Phillips H S | 1992 | Endorinology1992，131，1： | 1 |
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