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| 1 | Cellulose based polymers in development of amorphous solid dispersions显示文摘Cellulose derivatives have gained immense popularity as stabilizers for amorphous solid dispersion owing to their diverse physicochemical properties. More than 20 amorphous solid dispersion-based products that have been approved for marketing consist of cellulose derivatives as stabilizers, thus highlighting their importance in generation of amorphous solid dispersions. These polymers offer numerous advantages like drug solubilization, crystallization inhibition and improvement in release patterns of drugs. Exploring their potential and exploiting their chemistry and p H responsive behaviour have led to the synthesis of new derivatives that has broadened the scope of the use of cellulose derivatives in amorphous formulation development. The present review aims to provide an overview of different mechanisms by which these cellulose derivatives inhibit the crystallization of drugs in the solid state and from supersaturated solution. A summary of different categories of cellulose derivatives along with the newly explored polymers has been provided. A special segment on strengths, weaknesses, opportunities, and threats(SWOT) analysis and critical quality attributes(CQAs) which affect the performance of the cellulose based amorphous solid dispersion will aid the researchers in identifying the major challenges in the development of cellulose based solid dispersion and serve as a guide for further formulation development. | Rahul B Chavan Sneha Rathi Vaskuri G S Sainaga Jyothi Nalini R Shastri | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，3： | 5 |
| 2 | Traditional Indian anti-diabetic plants attenuate progression of renal damage in streptozotocin induced diabetic mice显示文摘 | J.K Grover V Vats S.S Rathi R Dawar | 2001 | Journal of Ethnopharmacology2001，，3： | 2 |
| 3 | N-(2-hydroxypropyl) nvethacrylamide copolymers containing pendant saccharide moieties: Synthesis and bioadhesive propertie 显示文摘 | Rathi R C Kopeckova P Rihova B A | 1991 | Journal of Polymer Science Part A: Polymer Chemistry (S0887-624X)1991，29，13： | 1 |
| 4 | Biodegradable block copolymers for delivery of proteins and water-insoluble drugs 显示文摘 | ZENTNER GM RATHI R SHIH C | 2001 | J Control Release2001，72，13： | 1 |
| 5 | Exponentially damped L6vy flights显示文摘 | Matsushita R Rathie P Silva S D | 2003 | Physica A: Statistical Mechanics and Its Applica- tions2003，326，3： | 1 |
| 6 | Allocating resources to support a mutli-commodity flow with time windows显示文摘 | Rathi A K Church R Solanki R | 1992 | Logistics and Transportation Review1992，28，2： | 1 |
| 7 | Biomarkers for hepatocellular cancer显示文摘Hepatocellular carcinoma(HCC)is the third leading cause of cancer-related deaths worldwide.If diagnosed early,curative treatment options such as surgical resection,loco-regional therapies,and liver transplantation are available to patients,increasing their chances of survival and improving their quality of life.Unfortunately,most patients are diagnosed with late stage HCC where only palliative treatment is available.Therefore,biomarkers which could detect HCC early with a high degree of sensitivity and specificity,may play a crucial role in the diagnosis and management of the disease.This review will aim to provide an overview of the different biomarkers of HCC comprising those used in the diagnosis of HCC in at risk populations,as well as others with potential for prognosis,risk predisposition and prediction of response to therapeutic intervention. | Gurjot Singh Eric M Yoshida Sahaj Rathi Vladimir Marquez Peter Kim Siegfried R Erb Baljinder S Salh | 2020 | World Journal of Hepatology2020，12，9： | 1 |
| 8 | Allocating resources to support a multicommodity flow with time windows显示文摘 | Rathi A K Solanki R S Church R L | 1993 | Logistics and Transportation Review1993，28，1： | 1 |
| 9 | Bacterial lipases:an overviewof production, purification and biochemical properties 显示文摘 | Gupta R Gupta N Rathi P | 2004 | ApplMicrobiol BiotecKnoI2004，64，6： | 1 |
| 10 | Bacterial lipases: an overview of pro- duction, purification and biochemical properties显示文摘 | Gupta R Gupta N Rathi P | 2004 | Applied Mi- crobiology and Biotechnology2004，64，6： | 1 |
| 11 | A novel alkaline lipase from Burkholderia cepacia for detergent formulation显示文摘 | Rathi P Saxena R K Gupta R et a/ | 2001 | Process Biochem2001，37，： | 1 |
| 12 | Bacterial hpases : an overview of production, purification and biochemical properties 显示文摘 | Gupta R Gupta N Rathi P | 2004 | Appl Microbiol Biotechnol2004，64，6： | 1 |
| 13 | Bacterial lipases: an overview of production, purification and biochemical properties显示文摘 | Gupta R Gupta N Rathi P | 2004 | Applied Microbiology and Bioteehnology2004，64，6： | 1 |
| 14 | Biodegradableblock copolymers for delivery of proteins and water-insoluble drugs显示文摘 | Zentner G M Rathi R Shih C | 2001 | J Control Release2001，72，13： | 1 |
| 15 | Allocating resources to support a multicommodity flow with time window显示文摘 | RATHI A K CHURCH R L SOLANKI R S | 1992 | Logistics and Transportation Review1992，28，： | 1 |
| 16 | Bacterial lipases:An overview of production,purification and biochemical properties显示文摘 | Gupta R Gupta N Rathi P | 2004 | Applied Microbiology and Biotechnology2004，64，： | 1 |
| 17 | Biodegradable block copolymers for delivery of proteins and water-insoluble drugs 显示文摘 | Zentner GM Rathi R Shih C | 2001 | J Control Rel2001，72，13： | 1 |
| 18 | Allocating Resources to Support a Multi - Commodity Flow with Time Windows 显示文摘 | Rathi A K R L ChurCh R S Solanki | 1993 | Logistics and Transportation Review1993，28，： | 1 |
| 19 | Suppression of spermatogenesis before grafting increases survival and supports resurgence of spermatogenesis in adult mouse testis显示文摘 | Arregui L Rathi R Modelski M | 2012 | Fertil Steril2012，97，6： | 1 |
| 20 | Biodegradable bl- ock copolymers for delivery of proteins and water-insolu- ble drugs显示文摘 | Zenmer GM Rathi R Shih C | 2001 | J Control Release2001，72，13： | 1 |
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