|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 曲马多治疗糖尿病性神经疼痛的双盲随机试验显示文摘目的 :本研究旨在评价曲马多治疗糖尿病性神经痛的有效性和安全性。背景 :糖尿病性神经痛是糖尿病患者的主要症状 ,其治疗和其他的末梢神经病变一样 ,不能令人满意。曲马多是作用于中枢的镇痛剂 ,用于治疗中到重度疼痛。方法 :多中心、门诊病例、随机、双盲、安慰剂做对照、设置平行组的研究 ,包括清洗期 (在此期间停用所有镇痛剂 )和一个为期 42天的双盲治疗期。总共有 1 31名患糖尿病性神经痛的患者按每日 4次接受了曲马多 (n =65)或看上去与曲马多相同的安慰剂胶囊治疗 (n =66)。 42天的治疗结束后或治疗中断后比较曲马多组和安慰剂组平均疼痛强度评分作出主要有效性分析 ;次要有效性分析为疼痛缓解率评分和根据日常活动和睡眠状况作出的对生活质量的评估。结果 :曲马多平均剂量为 2 1 0mg/天 ,治疗糖尿病性神经痛较安慰剂有显著疗效 (P≤ 0 .0 0 1 )。曲马多组患者生理(P =0 .0 2 )和社会功能 (P =0 .0 4 )的评分显著优于安慰剂组。未发现对睡眠有显著治疗作用。曲马多最常见的不良反应是恶心 ,便秘 ,头疼和嗜睡。结论 | Harati Y Gooch C Swenson M Green D Raskin P Donofrio P Cornblath D Sachdeo R Siu CO Kamin M | 2001 | 中国疼痛医学杂志2001，7，1： | 2 |
| 2 | Initiating insulin therapy in type 2 diabetes:a comparison of biphasic and basal insulin analogs显示文摘 | Raskin R Allen E Hollander P | | Diabetes Care0，，： | 2 |
| 3 | The value of the world’s ecosystemservices and natural capita1显示文摘 | Costanza R Arge R Groot R Farberk S Grasso M HannonB Limburg K Naeem S O’Neil R Paruelo J Raskin R Suttonkk P &Belt M | 1997 | Nature1997，387，： | 1 |
| 4 | Bioconcentration of heavy metal by plants显示文摘 | RASKIN I KUMER N P DUSHENKOV S | 1994 | Current Opinion in Biotechnology1994，5，： | 1 |
| 5 | Comparison of insulin detemir and insulin glargine using a basal-bolus regimen in a randomized, con -trolled clinical study in patients with type 2 diabetes显示文摘 | Raskin P Gylvin T Weng W | 2009 | Diabetes Metab Res Rev2009，25，6： | 1 |
| 6 | The effect of puhnonary rehabilitation on heahhcare utilization in chronic obstructive pulmonary disease: The Northeast Puhnonary Rehabilitation Consortium 显示文摘 | Raskin J Spiegler P McCusker C | 2006 | Journal of Cardiopulmonary Rehabilitation2006，26，4： | 1 |
| 7 | Salicylic acid, a likely endogenous signal in the resistance response of tobacco to viral infection显示文摘 | Malamy J Carr J P Klessig D F Raskin I | 1990 | Science1990，，250： | 1 |
| 8 | Randomized study of tramadol/acetaminophen versus placebo in painful diabetic peripheral neuropathy 显示文摘 | Freeman R Raskin P Hewitt DJ : CAPSS -237 Study Group | 2007 | Curr Med Res Opin2007，23，1： | 1 |
| 9 | Local- ization, conjugation, and function of salicylic acid in tobacco dur- ing the hypersensitive reaction to tobacco mosaic virus显示文摘 | ENYEDI A J YALPANI N SILVERMAN P RASKIN I | 1992 | Proceed- ings of the National Academy of Sciences of the United States of America1992，89，： | 1 |
| 10 | Airborne signaling bymethyl salicylate in plant pathogen resistance显示文摘 | Shulaev V Silverman P Raskin I | 1997 | Nature1997，385，： | 1 |
| 11 | Initiating insulin therapy in type 2 diabetes显示文摘 | Raskin P Allen E Hollander P | 2005 | Diabetes Care2005，28，2： | 1 |
| 12 | Efficacy and safety of insulin detemir显示文摘 | Raskin P | 2007 | Endocrinol Metab Clin North Am2007，36，1： | 1 |
| 13 | Hypertension management in adults with diabetes 显示文摘 | Arauz-Pacheco C Parrott MA Raskin P | 2004 | Diabetes Care2004，27，1： | 1 |
| 14 | Comparison of insulin detemir and insulin glargine using a basal-bolus regimen in a randomized,controlled clinical study in patients with type 2 diabetes显示文摘 | Raskin P Gylvin T Weng W | | 0，，： | 1 |
| 15 | The hypercalciuria of diabetes meUitus:its amelioration with insulin显示文摘 | Stevenson MR Barilla DE | 1978 | Clin Endoerinol1978，9，4： | 1 |
| 16 | A randomized trial of rosiglitazone therapy in patients with inadequately controlled insulin treated type diabetes显示文摘 | Raskin P Rendll M Riddie MC | 2001 | Diabetes Care2001，24，4： | 1 |
| 17 | The diabetic lung: relevance of alveolarmicroangiopathy for the use of inhaled insulin 显示文摘 | Hsia CC Raskin P | 2005 | Am J Med2005，118，3： | 1 |
| 18 | Twice-daily and three-times-daily dosing of a repaglinide/rnetformin fixed-dose combination tablet provide similar glycaemic conlrol显示文摘 | Raskin P Lewin A Reinhardt R | 2009 | Diabetes Obes Metab2009，11，10： | 1 |
| 19 | Bardoxolone methyl and kidney function in CKD with type 2 diabetes 显示文摘 | Pergola PE Raskin P Toto RD | 2011 | N Engl J Med2011，365，： | 1 |
| 20 | Comparison of insulin detemir and insulin glargine using a basal-bolus regimen in a randomized,controlled clinical study in patients with type 2 diabetes显示文摘 | Raskin P Gylvin T Weng W | | 0，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员