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| 1 | 国际胃袖状切除专家共识:基于>12000手术病例的最佳操作指南显示文摘腹腔镜胃袖状切除术(1aparoscopic sleeve gastrectomy,LSG)系相对较新的减重手术方式。因其操作相对简单、治疗肥胖合并疾病及减重效果明显,逐步得以广泛接受。目前美国代谢与减重手术协会将其推荐为肥胖症治疗的单独标准术式。2011年3月25~26日, | 苏远涛 徐安安 朱江帆 Diaz AA Arvidsson D Baker RS Basso N Bellanger D Boza C El Mourad H France M Gagner M Galvao-Neto M Higa KD Himpens J Hutchinson CM Jacobs M Jorgensen JO Jossart G Lakdawala M Nguyen NT Nocca D Prager G Pomp A Ramos AC Rosenthal RJ Shah S Vix M Wittgrove A Zundel N | 2013 | 中国微创外科杂志2013，13，9： | 12 |
| 2 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 3 | CD14,a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein显示文摘 | Wright S D Ramos R A Tobias P S | 1990 | Science1990，249，4975： | 2 |
| 4 | Analytical and mineralogical studies of ore and impurities from a chromite mineral using X - ray analysis, electrochemical and microscopy techniques 显示文摘 | Ramos S S Carbo A D Adelantado J V | 2008 | Talanta2008，74，5： | 1 |
| 5 | The Asiatic Clam Corbicula-Fluminea(Muller,1774) (Bivalvia,Corbiculidae) in Europe显示文摘 | Moreno D Ramos M A | 1993 | American Malacological Bulletin1993，10，1： | 1 |
| 6 | Char- acterization and dehydrogenation activity of Pt/Nb2 05 catalysts显示文摘 | Aranda D A G Ramos A L D Passos F B | 1996 | Catalysis Today1996，28，12： | 1 |
| 7 | Mathematical simulation and physical modeling of unsteady fluid flow in a water model of a slab mold显示文摘 | Ramos Banderaset A Morales R D | 2004 | Metallurgical and Material Transactions: B2004，35，3： | 1 |
| 8 | Comparison of quantitative PCR and antigenemia in cytomegalovirus infection in renal transplant recipients显示文摘 | Bordils A Plumed JS Ramos D | 2005 | Transplant Proc2005，37，9： | 1 |
| 9 | Clinicopathologic characteristics of gastric cancer in a young patient population 显示文摘 | Ramos D A Salgado N N Torres V G | 2004 | J Gastrointest Surg2004，8，3： | 1 |
| 10 | Ectopic thyroid presenting as a submandibular mass显示文摘 | BERSANETI J A SILVA R D RAMOS R R | 2011 | Head Neck Pathol2011，5，： | 1 |
| 11 | The structure of the N-terminal domain of the fragile X mental retardation protein:a platform for protein-protein interaction显示文摘 | RAMOS A HOLLINGWORTH D Adinolfi S | 2006 | Structure2006，14，： | 1 |
| 12 | Clear cell sarcoma of tendons and aponeurosis: a clinico-pathologic study of 58 cases with analysis of prognostic factors显示文摘 | Montgomery E A Meis J M Ramos A G Frisman D M MartzK L | 1993 | Int J Surg Pathol1993，1，： | 1 |
| 13 | Correlates of tobacco dependence and motivation to quit among young people receiving mental health treatment显示文摘 | Grana R A Ramo D E Fromont S C | 2012 | Drugand alcoholdependence2012，125，1： | 1 |
| 14 | Role of dehydration catalyst acid properties on one-step DME synthesis over physical mixtures显示文摘 | Ramos F S De Farias A M D Borges L E P | 2005 | Catal Today2005，101，1： | 1 |
| 15 | Thyroid suppression test with L - thyroxine and per-technetate 显示文摘 | RAMOS C D ZANTUT WITTMANN D E TAMBASCIA M A etal | 2000 | Clin Endocrinol ( Oxf)2000，52，4： | 1 |
| 16 | Identification of a gene overexpressed in aphids reared under short photoperiod 显示文摘 | Ramos S Moya A Martinez-Torres D | 2003 | In- sect Biochemistry and Molecular Biology2003，33，3： | 1 |
| 17 | Stability to gastrointestinal enzymes and structure-activity relationship of beta-casein-peptides with antihypertensive properties显示文摘 | A Quiros M D Contreras M Ramos | 2009 | Peptides2009，30，10： | 1 |
| 18 | Antigen specific CD4 T cell drive airway smooth muscle remodeling in experimental asthma 显示文摘 | Ramos Barb6n D Presley J F Hamid Q A | 2005 | J Clin Invest2005，115，6： | 1 |
| 19 | Functional results of two different surgical appruaches in patients with distal humans fractures type C (AO) 显示文摘 | Mejia Silva D Morales de los Santos R Cienega Ramos M A | 2008 | Acta Ortop Mex2008，，： | 1 |
| 20 | Inhibitor-sensi- tive FGFR-1 amplification in human non-small cell lung cancer显示文摘 | Amit D Ramos A Hammerman P | 2011 | Plos One2011，6，6： | 1 |
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