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| 1 | Prospective randomized controlled trial evaluating cap-assisted colonoscopy vs standard colonoscopy显示文摘AIM: To study the significance of cap-fitted colonoscopy in improving cecal intubation time and polyp detection rate. METHODS: This study was a prospective randomized controlled trial conducted from March 2008 to February 2009 in a tertiary referral hospital at Sydney. The primary end point was cecal intubation time and the secondary endpoint was polyp detection rate. Consecutive cases of total colonoscopy over a 1-year period were recruited. Randomization into either standard colonoscopy (SC) or cap-assisted colonoscopy (CAC) was performed after consent was obtained. For cases randomized to CAC, one of the three sizes of cap was used: D-201-15004 (with a diameter of 15.3 mm), D-201-14304 (14.6 mm) and D-201-12704 (13.0 mm). All of these caps were produced by Olympus Medical Systems, Japan. Independent predictors for faster cecal time and better polyp detection rate were also determined from this study. RESULTS: There were 200 cases in each group. There was no signif icant difference in terms of demographic characteristics between the two groups. CAC, when compared to the SC group, had no signif icant difference in terms of cecal intubation rate (96.0% vs 97.0%, P = 0.40) and time (9.94 ± 7.05 min vs 10.34 ± 6.82 min, P = 0.21), or polyp detection rate (32.8% vs 31.3%, P = 0.75). On the subgroup analysis, there was no significant difference in terms of cecal intubation time by trainees (88.1% vs 84.8%, P = 0.40), ileal intubation rate (82.5% vs 79.0%, P = 0.38) or total colonoscopy time (23.24 ± 13.95 min vs 22.56 ± 9.94 min, P = 0.88). On multivariate analysis, the independent determinants of faster cecal time were consultant-performed procedures (P < 0.001), male patients (P < 0.001), non-usage of hyoscine (P < 0.001) and better bowel preparation (P = 0.01). The determinants of better polyp detection rate were older age (P < 0.001), no history of previous abdominal surgery (P = 0.04), patients not having esophagogastroduodenoscopy in the same setting (P = 0.003), trainee-performed procedures (P = 0.01), usage of hyoscine (P = 0.01) and procedures performed for polyp follow-up (P = 0.01). The limitations of the study were that it was a single-center experience, no blinding was possible, and there were a large number of endoscopists. CONCLUSION: CAC did not signif icantly different from SC in term of cecal intubation time and polyp detection rate. | Hoi-Poh Tee Crispin Corte Hamdan Al-Ghamdi Emilia Prakoso John Darke Raman Chettiar Wassim Rahman Scott Davison Sean P Griffin Warwick S Selby Arthur J Kaffes | 2010 | World Journal of Gastroenterology2010，16，31： | 10 |
| 2 | Photoluminescence study of SiC nanotubes显示文摘 | Nagarajan K Raman S K | 2008 | Bulg J Phys2008，35，1： | 1 |
| 3 | An analytical model for optimization of NC tool cutting path显示文摘 | LAKKARAJU R K RAMAN S IRANI S A | 1992 | Int J Prod Res1992，30，1： | 1 |
| 4 | A new type of secondary radiation显示文摘 | Raman C V Krishnan K S | 1928 | Nature1928，121，3048： | 1 |
| 5 | Isolation and purification of closely related Citrus limonoid glucosides by flash chromatography显示文摘 | Raman G Cho M Brodbelt J S | 2005 | Phytochemical Analysis2005，16，3： | 1 |
| 6 | Nanoscale as semblies and their biomedical applications显示文摘 | Doll TA Raman S Dey R | 2013 | J R Soe Interface2013，0，80： | 1 |
| 7 | New potenti adjuncts to reatnlent of children with type 1 diabetes mellitus显示文摘 | Raman V S Heptulla R A | 2009 | Pediatr Res2009，65，： | 1 |
| 8 | In vitro degradation and mechanical integrity of calcium-containing magnesium alloys in modified-simulated body fluid 显示文摘 | Kannan M B Raman R K S | 2008 | Biomaterials2008，29，15： | 1 |
| 9 | Evolutionarily conserved,DMRT1,encodes alternatively spliced transcripts and shows dimorphic expression during gonadal differentiation in the lizard,calotes versicolor显示文摘 | Ganesh S Raman R | 2002 | Gene Expression Patterns2002，2，2： | 1 |
| 10 | A 28-W portable direct borohydride-hydrogen peroxide fuel-cell stack 显示文摘 | RAMAN R K PRASHANT S K SHUKLA A K | 2006 | Journal of Power Sources2006，162，： | 1 |
| 11 | Beaded reactive polymer immobilization of penicillin G acylase on glycidyl methacrylate-divinyl benzene copolymers of differing pore size and its distribution显示文摘 | KOTHA A RAMAN R C PONRATHNAM S | 1996 | React Funct Polym1996，28，3： | 1 |
| 12 | Synthesis of silicon carbide nanofibers by sol-get and polymer blend techniques 显示文摘 | Raman V Bhatia G Bhardwaj S | 2005 | Joural of Materials Science2005，40，： | 1 |
| 13 | Magnesium alloys as body implants: Fracture mechanism under dynamic and static loadings in a physiological environment显示文摘 | Choudhary L Raman R K S | 2012 | Acta Biornaterialia2012，8，2： | 1 |
| 14 | Feature-based operation sequence generation in CAPP 显示文摘 | Irani S A Koo H Y Raman S | 1995 | lnternational Journal of Production Research1995，33，1： | 1 |
| 15 | Acute orthostatic hypotension when starting dopamine agonists in Parkinson's disease 显示文摘 | Kujawa K Leurgans S Raman R | 2000 | Arch Neurol2000，57，10： | 1 |
| 16 | Association of VEGF gene polymorphisms with diabetic retinopathy in a south Indian cohort显示文摘 | Uthra S Raman R Mukesh BN | 2008 | Ophthalmic Genet2008，29，1： | 1 |
| 17 | Intelligent search-based selection of sample points for straightness and flatness estimation显示文摘 | BADAR M A RAMAN S PULAT P S | 2003 | Journal of Manufacturing Science and Engineering2003，125，： | 1 |
| 18 | MR spectroscopic ima- ging and diffusion-weighted imaging of prostate cancer with Glea- son scores显示文摘 | Nagarajan R Margolis D Raman S | 2012 | J Magn Reson Imaging2012，36，3： | 1 |
| 19 | Influence of Microarc Oxidation and Hard Anodizing on Plain Fatigue and Fretting Fatigue Behaviour of Al-Mg-Si Alloy显示文摘 | RAJASEKARAN B GANESH SUNDARA RAMAN S RAMA KRISHNA L | 2008 | Surface and Coatings Technology2008，202，8： | 1 |
| 20 | An intelligent sampling method for inspecting free-form surfaces 显示文摘 | Obeidat S M Raman S | 2009 | The International Journal of Advanced Manufacturing Technology2009，40，1112： | 1 |
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