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| 1 | Prospective randomized controlled trial evaluating cap-assisted colonoscopy vs standard colonoscopy显示文摘AIM: To study the significance of cap-fitted colonoscopy in improving cecal intubation time and polyp detection rate. METHODS: This study was a prospective randomized controlled trial conducted from March 2008 to February 2009 in a tertiary referral hospital at Sydney. The primary end point was cecal intubation time and the secondary endpoint was polyp detection rate. Consecutive cases of total colonoscopy over a 1-year period were recruited. Randomization into either standard colonoscopy (SC) or cap-assisted colonoscopy (CAC) was performed after consent was obtained. For cases randomized to CAC, one of the three sizes of cap was used: D-201-15004 (with a diameter of 15.3 mm), D-201-14304 (14.6 mm) and D-201-12704 (13.0 mm). All of these caps were produced by Olympus Medical Systems, Japan. Independent predictors for faster cecal time and better polyp detection rate were also determined from this study. RESULTS: There were 200 cases in each group. There was no signif icant difference in terms of demographic characteristics between the two groups. CAC, when compared to the SC group, had no signif icant difference in terms of cecal intubation rate (96.0% vs 97.0%, P = 0.40) and time (9.94 ± 7.05 min vs 10.34 ± 6.82 min, P = 0.21), or polyp detection rate (32.8% vs 31.3%, P = 0.75). On the subgroup analysis, there was no significant difference in terms of cecal intubation time by trainees (88.1% vs 84.8%, P = 0.40), ileal intubation rate (82.5% vs 79.0%, P = 0.38) or total colonoscopy time (23.24 ± 13.95 min vs 22.56 ± 9.94 min, P = 0.88). On multivariate analysis, the independent determinants of faster cecal time were consultant-performed procedures (P < 0.001), male patients (P < 0.001), non-usage of hyoscine (P < 0.001) and better bowel preparation (P = 0.01). The determinants of better polyp detection rate were older age (P < 0.001), no history of previous abdominal surgery (P = 0.04), patients not having esophagogastroduodenoscopy in the same setting (P = 0.003), trainee-performed procedures (P = 0.01), usage of hyoscine (P = 0.01) and procedures performed for polyp follow-up (P = 0.01). The limitations of the study were that it was a single-center experience, no blinding was possible, and there were a large number of endoscopists. CONCLUSION: CAC did not signif icantly different from SC in term of cecal intubation time and polyp detection rate. | Hoi-Poh Tee Crispin Corte Hamdan Al-Ghamdi Emilia Prakoso John Darke Raman Chettiar Wassim Rahman Scott Davison Sean P Griffin Warwick S Selby Arthur J Kaffes | 2010 | World Journal of Gastroenterology2010,16,31: | 10 |
| 2 | Solubilization of trichloroacetic acid(TCA)precipitated microbial Proteins via NaOH for two-dimensional electrophoresis显示文摘 | Nandaknmar M P Shen J Raman B | 2003 | J Proteome Res2003,2,: | 1 |
| 3 | Studies on blends of epoxy-funetionalized hyperbranched polymer and epoxy resin 显示文摘 | PATNA D VARLEY RUSSELL J SINGH RAMAN RK | 2003 | Journal of Material Science2003,38,1: | 1 |
| 4 | Suppression of accelerated diabetic atheresclerosis by the soluble receptor for advanced glycation endproducts 显示文摘 | PARK L RAMAN K G LEE K J | 1998 | Nat Med1998,4,: | 1 |
| 5 | Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts 显示文摘 | PARK L RAMAN K G LEE K J | 1998 | Nat Med1998,4,: | 1 |
| 6 | Isolation and purification of closely related Citrus limonoid glucosides by flash chromatography显示文摘 | Raman G Cho M Brodbelt J S | 2005 | Phytochemical Analysis2005,16,3: | 1 |
| 7 | Glutamine improves myocardial function following ischemia-reperfusion injury显示文摘 | BOLOTIN G RAMAN J WILLIAMS U | 2007 | Asian Cardiovasc Thorac Ann2007,15,: | 1 |
| 8 | Engineered microbial sys-tems for enhanced conversion of lignocellulosic biomass 显示文摘 | Elkins J G Raman B Keller M | 2010 | Curr Opin Biotechnol2010,21,: | 1 |
| 9 | Detecting insect flight sounds in the field:Implications for acoustical counting of mosquitoes显示文摘 | Raman D R Gerhardt R R Wilkerson J B | 2007 | Transactions of the ASABE2007,50,4: | 1 |
| 10 | Response of refractory Kawasaki disease to pulse steroid and cyclosporin A therapy显示文摘 | Raman V Kim J Sharkey A | | 0,,06: | 1 |
| 11 | Role of chemokines in tumor growth显示文摘 | Raman D Baugher P J Thu Y M Richmond A | 2007 | Cancer Lett2007,256,: | 1 |
| 12 | Rigid palte fixation of the sternum显示文摘 | Raman J Straus D Song DH | 2007 | Ann Thorac Surg2007,84,3: | 1 |
| 13 | Mantrala ( 1994 ), Finding choice alternatives in memory: probability models of brand name recall显示文摘 | Hutchinson J Wesley Kalyan Raman and Murali K | 1994 | Journal of Marketing Research1994,31,: | 1 |
| 14 | Optimized shapes of oscillating resonators for generating high-amplitude pressure waves显示文摘 | LI X F FINKBEINER J RAMAN | 2004 | Journal of the Acoustic Society of America2004,116,5: | 1 |
| 15 | Real-time cerebral angiography:sensitivity of a new contrast-specific ultra-sound technique 显示文摘 | Holscher T Sattin J A Raman R | 2007 | AJNR Am J Neuroradiol2007,28,4: | 1 |
| 16 | Primary sternal closure with titanium plate fixation:plastic surgery effecting a paradigm shift显示文摘 | Lee JC Raman J Song DH | 2010 | Plast Reconstr Surg2010,125,6: | 1 |
| 17 | Serial cardiac magnetic resonance imaging of injected mesenchymal stem cells 显示文摘 | Hill J M Dick A J Raman V K | 2003 | Circulation2003,108,8: | 1 |
| 18 | Assessment of mitral valve leaflet perforation as a result of infective endocarditis by 3-dimensional real-time echocardiography 显示文摘 | Schwalm SA Sugeng L Raman J | 2004 | J Am Soc Echocardiogr2004,17,: | 1 |
| 19 | Image and video encryption based on dual space-filling curves 显示文摘 | Bhatnagar G Wu Q W J Raman B | 2012 | Com- puter Journal2012,55,6: | 1 |
| 20 | Management options for lo - wet pole renal calculi 显示文摘 | RAMAN J D PEARLE M S | 2008 | Curr Opin Urol2008,18,: | 1 |