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| 1 | Multiple genetic alterations and behavior of cellular biology in gastric cancer and other gastric mucosal lesions:H.pylori infection,histological types and staging显示文摘AIM To investigate the expression of multiplegenes and the behavior of cellular biology ingastric cancer(GC)and other gastric mucosallesions and their relations to Helicobacter pylori(H.pylori)infection,tumor staging andhistological subtypes.METHODS Three hundred and twenty-sevenspecimens of gastric mucosa obtained viaendoscopy or surgical resection,and ABCimmunohistochemical staining were used todetect the expression of p53,p16,Bcl-2 andCOX-2 proteins.H.pylori was determined byrapid urea test combined with pathologicalstaining or14C urea breath test.Cellular image analysis was performed in 66 patients withintestinal metaplasia(IM)and/or dysplasia(Dys).In 30 of them,both cancer and theparacancerous tissues were obtained at the timeof surgery.Histological pattern,tumor staging,lymph node metastasis,grading ofdifferentiation and other clinical data werestudied in the medical records.RESULTS p16 expression of IM or Dys wassignificantly lower in positive H.pylori chronicatrophic gastritis(CAG)than those withnegative H.pylori(CAG:54.8% vs 88.0%,IM:34.4% vs 69.6%,Dys:23.8% vs 53.6%,allP<0.05),Bcl-2 or COX-2 expression of IM orDys in positive H.pylori cases was significantlyhigher than that without H.pylori(Bcl-2:68.8%vs23.9%,90.5% vs 60.7%;COX-2:50.0% vs10.8%,61.8% vs 17.8%;all P<0.05).Themean number of most parameters of cellularimage analysis in positive H.pylori group wassignificantly higher than that in negative H.pylori group(Ellipser:53±14,40±12μm,Area1:748±572,302±202 μm2,Area2:3050±1661,1681±1990 μm2,all P<0.05;Ellipseb:79±23,58±15 μm,Ratio1:22%±5%,13%±4%,Ratio2:79%±17%,53%±20%,all P<0.01).There was significant correlation between Bcl-2and histologic pattern of gastric carcinoma,andbetween COX-2 and tumor staging or lymph nodemetastasis(Bcl-2:75.0% vs 16.7%;COX-2:76.0% vs 20.0%,79.2% vs 16.7%;allP<0.05).CONCLUSION p1l6, Bcl-2, and COX-2 but not p53 gene may play a role in the early genesis/ progression of gastric carcinoma and are associated with H. pylori infection. p53 gene is relatively late event in gastric tumorigenesis and mainly relates to its progression. There is more cellular-biological behavior of malignant tumor in gastric mucosal lesions with H. pylori infection. Aberrant Bcl-2 protein expression appears to be preferentially associated with the intestinal type cancer. COX-2 seems to be related to tumor staging and lymph node metastasis. | Heng Jun Gao Lian Zhen Yu Jian Feng Bai Yan Shen Peng Gu Sun Han Lin Zhao Kun Miu Xiu Zhen Lü Xiao Yong Zhang Zhi Quan Zhao | 2000 | World Journal of Gastroenterology2000，6，6： | 52 |
| 2 | CeCl_3·7H_2O as an efficient catalyst for one-pot synthesis of β-amino ketones by three-component Mannich reaction显示文摘Cerium trichloride heptahydrate(CeCl_3·7H_2O) was found to be an efficient and recyclable catalyst for the three-component direct Mannich reaction of anilines and benzaldehydes with acetophenone.This protocol has advantages of high yield,no environmental pollution,mild condition,and simple work-up procedure. | Yan Dai Chun Xu Lü | 2010 | Chinese Chemical Letters2010，21，1： | 10 |
| 3 | Mitigation of greenhouse gases released from mining activities:A review显示文摘Climate changes that occur as a result of global warming caused by increasing amounts of greenhouse gases(GHGs)released into the atmosphere are an alarming issue.Controlling greenhouse gas emissions is critically important for the current and future status of mining activities.The mining industry is one of the significant contributors of greenhouse gases.In essence,anthropogenic greenhouse gases are emitted directly during the actual mining and indirectly released by the energy-intensive activities associated with mining equipment,ore transport,and the processing industry.Therefore,we reviewed both direct and indirect GHG emissions to analyze how mining contributes to climate change.In addition,we showed how climate change impacts mineral production.This assessment was performed using a GHG inventory model for the gases released from mines undergoing different product life cycles.We also elucidate the key issues and various research outcomes to demonstrate how the mining industry and policymakers can mitigate GHG emission from the mining sector.The review concludes with an overview of GHG release reduction and mitigation strategies. | Li-yuan Liu Hong-guang Ji Xiang-feng Lü Tao Wang Sheng Zhi Feng Pei Dao-lu Quan | 2021 | International Journal of Minerals,Metallurgy and Materials2021，28，4： | 4 |
| 4 | Effect of strain,strain rate and temperature on workability of AZ80 wrought magnesium alloy显示文摘The hot deformation behavior of AZ80 wrought magnesium alloy was studied in the temperature range of 523-673 K and the strain rate range of 0.01-10 s-1 using hot compression tests.Through the flow stresses behavior,the processing maps were calculated and analyzed according to the dynamic materials model.The stable,metastable and unstable regimes were clarified.The optimum processing conditions were suggested as following:the DRX regions in Domain #1-0.25,Domain #2-0.25,Domain #1-0.45,Domain #2-0.45,Domain #3-0.45,Domain #1-0.65 and Domain #1-0.85,and the DRV regions in Domain #3-0.25 and Domain #4-0.45.In each 'safe' DRX domain,it is preferable to conduct hot working in the small region around efficiency peak point.The strain has a great influence on the processing maps.The whole area of the 'safe' domains increases with the increase of true strain from 0.25 to 0.65,while it decreases with the increase of true strain from 0.65 to 0.85.The results of kinetic analysis reveal that the values of apparent activation energy in all the domains are higher than that for self-diffusion in pure magnesium (135kJ/mol),and the deformation mechanism in all the domains is likely to be cross-slip. | Lü Wen-quan QUAN Guo-zheng YU Chun-tang ZHAO Lei ZHOU Jie | 2012 | 中国有色金属学会会刊:英文版2012，22，S3： | 2 |
| 5 | First Principle Calculation of Electromagnetic Mechanism for Fe_2Si Bulk Material显示文摘The electronic structure and the magnetic properties of Fe_2Si bulk have been calculated by the first-principle density function theory method. The band structure shows that the hexagonal Fe^2 Si bulk is ferromagnetic which is a metal structure under spin-up, and a semiconductor with the band gap of 0.518 eV under spin-down. The density of states shows the Fe^1 3d–spin and Fe^3 3d–spin in the electronic system are the main factors that is the source of the ferromagnetic properties of Fe_2Si bulk. The electronic structure Si-ions is 3s23p6 and that of Fe-ions is e_g^2↑e_g^(*1)↓t_(2g)~3↑. The molecular magnetic moment of Fe_2Si is 2.00 μB. The potential diagram of Fe_2Si bulk shows the formation of covalent and ionic bonds between the Fe atom and the Si atom, it leads to the center charge of Fe is polarized and off center position. These special properties of Fe_2Si bulk are mainly caused by d-d exchange and p-d hybridization. The results offer a certain reference for the magnetic semiconductor Fe_2Si material. | 李瑞杰 CEN Weifu 杨吟野 Lü Lin XIE Quan | 2019 | Journal of Wuhan University of Technology(Materials Science)2019，34，1： | 2 |
| 6 | 显示文摘 | Ni H L Zhang J S | 2001 | Polym Mat Sci Engin2001，17，5： | 1 |
| 7 | Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC显示文摘 | QUAN C REN Y Q XIANG L H | 2010 | Nat Genet2010，42，7： | 1 |
| 8 | Linear N-Point camera pose determination显示文摘 | QUAN L LAN Zhong-dan | 1999 | IEEE Transactions on Pattern Analysis and Machine Intelligence1999，21，7： | 1 |
| 9 | Advanced interpolation techniquesfor Nc machines显示文摘 | Bedi S Ali L Quan N | 1993 | Journal of Engineering for Industry1993，115，8： | 1 |
| 10 | Progressive inter-scale and intra- scale non-blind image deconvolution显示文摘 | Yuan L Sun J Quan L | 2008 | ACM Trans on Graph2008，27，3： | 1 |
| 11 | Development of multiplex PCR system with 15 X-STR loci and genetic analysis in three nationality popu- lations from China显示文摘 | Liu QL Lu DJ Quan L | 2012 | Electropharesis2012，33，8： | 1 |
| 12 | 显示文摘 | Quan X Yang S G Ruan X L | 2005 | Environ Sci Technol2005，39，： | 1 |
| 13 | Microbial degradation of quinQline by immobilized cells of Burkholderia pickettii 显示文摘 | Wang J L Quan X C Han L P | 2002 | Water Res2002，36，9： | 1 |
| 14 | Immunohistochemistryof pulmonary surfactant apoprotein A in forensic autopsy:reassessment in relation to the causes of death显示文摘 | Zhu B L Ishida K Quan L | 2000 | ForensicSci Int2000，13，13： | 1 |
| 15 | Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs 显示文摘 | Quan S Yang L Abraham NG | 2001 | Proc Natl Acad Sci USA2001，98，12： | 1 |
| 16 | Simultaneous pentachlorophenol decomposition and granular activated carbon regeneration assisted by microwave irradiation显示文摘 | LIU X T QUAN X BO L L | 2004 | Carbon2004，42，2： | 1 |
| 17 | Effect of midazolam on memory: a study of process dissociation procedure and functional magnetic resonance imaging显示文摘 | Tian SY Zou L Quan X | 2010 | Anaesthesia2010，65，： | 1 |
| 18 | Modified silica sol coatings for highly hydrophobic cotton and polyester fab- rics using a one-step procedure 显示文摘 | Quan Z Gao Q w Guo Y L | 2011 | Industrial & Engi- neering Chemistry Research2011，50，10： | 1 |
| 19 | 查看详情显示文摘 | Xie G H Zhang Z S Xue Q Zhang S M Zhao L Luo Y Chen E Quan B F Zhao Y Liu S Y | | 0，，： | 1 |
| 20 | A quasi-dense approach to surface reconstruction from uncalibrated images 显示文摘 | Lhuillier M Quan L | 2005 | IEEE Transactions on Pattern Analysis and Machine Intelligence(S0162-8828)2005，27，3： | 1 |
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