|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Improvedbiodesulfurization of hydrodesulfurized diesel oil usingrhodococcus erythropolis and gordonia sp显示文摘 | Li Guoqiang Li Shanshan Qu Shiwei | 2008 | Biotechno-logy Letters2008，30，10： | 1 |
| 2 | Chemometric identification of canonical metabolites linking critical process parameters to monoclonal antibody production during bioprocess development显示文摘A deeper understanding of the biological events occurring when bioprocess parameters changed will be of great value in improving the monoclonal antibodies (mAbs) production. Design of experiment (DoE) was applied to investigate the effect of process parameters (pH, temperature shift and dissolve oxygen (DO)) on protein titer. The key metabolites connecting the critical process parameters (CPPs) with monoclonal antibody production were identified by different chemometrics tools. Finally, the biological events of marker metabolites relating with titer improvement were concluded. pH and temperature shift were identified as CPPs that affect the target protein titer. A series of metabolites influenced by the altered CPPs and correlated with protein titer were screened by principal component analysis (PCA) and Pearson' correlation test. The marker metabolites and their pathways linking CPPs to target protein titer in different culture phases were summarized. Metabolomics and chemometrics are promising data-driven tools to shine light into the biological black box between the bioprocess parameters and process performance. | Lijuan Shen Xu Yan Lei Nie Wenyan Xu Shiwei Miao Haibin Wang H.Fai Poon Haibin Qu | 2019 | Chinese Journal of Chemical Engineering2019，27，5： | 1 |
| 3 | A broad-notched ultrawideband printed monopole antenna显示文摘 | QU Shiwei L1 Jialin XUE Quint | 2006 | IEEE Antennas and Wireless Propagation Letters2006，，5： | 1 |
| 4 | Wideband cavity-backed bowtie antenna with pattern improvement显示文摘 | Qu Shiwei Li Jialin Xue Quan | 2008 | IEEE Trans on Antennas and Propagation2008，56，12： | 1 |
| 5 | Ultrawideband composite cavity backed folded sectorial bowtie antenna with stable pattern and high gain显示文摘 | Qu Shiwei Chan Chihou Xue Quan | 2009 | IEEE Trans on Antennas and Propagation2009，57，8： | 1 |
| 6 | Wideband and high gain composite cavity-backed crossed triangular bowtie dipoles for circularly polar ized radiation显示文摘 | Qu Shiwei Chan Chihou Xue Quan | 2010 | IEEE Trans on Antennas and Propagation2010，58，10： | 1 |
| 7 | Bandwidth Enhancement of Wide-Slot Antenna Fed by CPW and Microstrip Line 显示文摘 | Shiwei Qu and Chengli Ruan | 2006 | IEEE antenna and wireless propagation letters2006，5，1： | 1 |
| 8 | Research on the Industrial Transfer and Restructuring Path of the Energy-Intensive Manufacturing Industry in Western China显示文摘The orderly transfer of the manufacturing industry is a major action in China’s industrial restructuring.From the perspective of industrial transfer,we used the concentration ratio to depict the trend of the industrial transfer of energy-intensive manufacturing in the eastern,central,and western regions since the policy of large-scale development of western China was implemented.We measured the total factor productivity(TFP)of western China using the DEAMalmquist index method.We conducted a regression analysis to measure the effect of western China’s undertaking of the transfer of the energy-intensive manufacturing industry.The findings of this study show that during 2000–2019,eleven provinces(as well as autonomous regions and municipalities)in western China undertook the transfer of the energy-intensive manufacturing industry from the eastern and central regions to varying degrees,exhibiting significant phase features regarding the rate and scale of transfers.Further investigation also demonstrated that the transfer of energy-intensive manufacturing industries has a U-shaped enabling effect on TFP in western China with the scale effect greater than the technology effect.Therefore,it is necessary to transition from“extensive industrial transfer”at the cost of the labor force,land,and resources to“modern industrial transfer”featured by technology and efficiency improvements to contribute to industrial restructuring in western China effectively. | Wang Fang Chen Shiwei Qu Tiantian | 2023 | Contemporary Social Sciences2023，8，2： | 0 |
| 9 | Performance of^(18)F‑DCFPyL PET/CT in Primary Prostate Cancer Diagnosis,Gleason Grading and D'Amico Classifcation:A Radiomics‑Based Study显示文摘This study aimed to investigate the performance of^(18)F-DCFPyL positron emission tomography/computerized tomography(PET/CT)models for predicting benign-vs-malignancy,high pathological grade(Gleason score>7),and clinical D'Amico classifcation with machine learning.The study included 138 patients with treatment-naïve prostate cancer presenting positive^(18)F-DCFPyL scans.The primary lesions were delineated on PET images,followed by the extraction of tumor-to-backgroundbased general and higher-order textural features by applying fve diferent binning approaches.Three layer-machine learning approaches were used to identify relevant in vivo features and patient characteristics and their relative weights for predicting high-risk malignant disease.The weighted features were integrated and implemented to establish individual predictive models for malignancy(Mm),high path-risk lesions(by Gleason score)(Mgs),and high clinical risk disease(by amico)(Mamico).The established models were validated in a Monte Carlo cross-validation scheme.In patients with all primary prostate cancer,the highest areas under the curve for our models were calculated.The performance of established models as revealed by the Monte Carlo cross-validation presenting as the area under the receiver operator characteristic curve(AUC):0.97 for Mm,AUC:0.73 for Mgs,AUC:0.82 for Mamico.Our study demonstrated the clinical potential of^(18)F-DCFPyL PET/CT radiomics in distinguishing malignant from benign prostate tumors,and high-risk tumors,without biopsy sampling.And in vivo^(18)F-DCFPyL PET/CT can be considered a noninvasive tool for virtual biopsy for personalized treatment management. | Yuekai Li Fengcai Li Shaoli Han Jing Ning Peng Su Jianfeng Liu Lili Qu Shuai Huang Shiwei Wang Xin Li Xiang Li | 2023 | Phenomics2023，3，6： | 0 |
| 10 | Alterations in gut microbiota and physiological factors associated with abdominal aortic aneurysm显示文摘Abdominal aortic aneurysm(AAA)is a progressive focal dilatation and weakening of the abdominal aorta,causing 1.3%of all deaths among men aged 65–85 years worldwide.The formation of AAA is a complex process with multiple risk factors.Therefore,this study aimed to determine the relationship of disease severity and physiological factors,and gut microbiota structures in AAA patients.Physiological indicators and fecal 16S rRNA gene sequences from healthy controls and patients with AAA were collected.The correlations between the diameter of the AAA and clinical parameters,and gut microbiota composition were then analyzed separately using multivariable analysis.The diameter of AAA was extremely positively correlated with smoking index,alkaline phosphatase,blood glucose,and blood triglycerides and negatively correlated with prealbumin and Cystatin C.As the diameter of AAA increased,the α-diversity,including Chao 1,Shannon,and Simpson indices,of the gut microbiota decreased and presented a negative linear relationship.Patients with AAA with more severe disease had significantly increased relative abundance of Enterobacteriaceae and decreased relative abundance of Veillonellaceae.A strong correlation was observed between the diameter and physiological data,as well as between diameter and gut microbiota composition.This study could improve the understanding of AAA,and gut microbiota may be a potential target to prevent and treat this deadly disease. | Kun Zhang Shiwei Yang Yingchun Huang Xian Qin Kai Qu Yidan Chen Lizhao Chen Juhui Qiu Yingxue Hao Guixue Wang | 2022 | Medicine in Novel Technology and Devices2022，，2： | 0 |
| 11 | Preparation of waterborne polyurethane/β-cyclodextrin composite nanosponge by ion condensation method and its application in removing of dyes from wastewater显示文摘Currently,polymer nanosponges have received extensive attention.However,developing new synthetic techniques for novel nanosponges remains a challenge.Furthermore,to date,composite nanosponge adsorbents based on waterborne polyurethane(WPU)andβ-cyclodextrin(β-CD)have not been reported.Herein,a novel green method,ion condensation method,was developed in this study for the preparation of polymer nanosponge adsorbents for efficient removal of dyes from wastewater.Based on the principle of charge repulsion between nanoparticles to maintain emulsion stability,waterborne polyurethane/β-cyclodextrin composite nanosponges(WPU-x,y)were prepared by coagulating the emulsions synthesized from 2,2-dimethylolpropionic acid,polypropylene glycol and hexamethylene diisocyanate as raw materials in a mixture of hydrochloric acid and anhydrous ethanol.The structure and appearance of WPU-x,y were characterized by attenuated total reflectance Fourier transform infrared spectroscopy,thermal gravimetric analyzer,scanning electron microscope and mercury intrusion porosimetry.The adsorption capacity of WPU-x,y was tested by parameters such as cross-linking degree,β-CD dosage,contact time,initial dye concentration and p H value.The study found that WPU-4,4.62 had the best adsorption effect on methylene blue(MB),the maximum removal rate was 93.42%,and the maximum adsorption capacity was 136.03 mg·g^(-1).Moreover,the Sips isotherm and pseudo-second-order-model were suitable for MB adsorption.Therefore,this study provides some perspectives for the fabrication of nanosponge adsorbents. | Shanghong Ma Haitao Zhang Jianbo Qu Xiuzhong Zhu Qingfei Hu Jianyong Wang Peng Ye Futao Sai Shiwei Chen | 2023 | Chinese Journal of Chemical Engineering2023，58，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员