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| 1 | Cumulate complex xenoliths in the Early Mesozoic in eastern Inner Mongolia显示文摘Mafic xenoliths occur in Mesozoic diorites from nine localities in eastern Inner Mongolia from the Da Hinggan Mrs. to Huabei craton. Their petrologic and geochemical features suggest that they are an intact suite of cumulate complex whose mineral assemblages contain typical patent mantle metasomatism minerals such as pargosite, phlogopite and apatite. Their REEs and trace element characteristics suggest a comagmatic relationship in these cumulates with different compositions. Isotopic dating of the xenoliths indicates that they are products of the mantle magmatic underplating in the Early Mesozoic (237—224 Ma), and they may provide direct evidence for the crust-mantle interaction and vertical accretion of continental crust under a background of the mantle upwelling in the Early Mesozoic in Huabei region. | Ji’an Shao Qingjun Han Luqiao Zhang Baolei Mu | 1999 | Chinese Science Bulletin1999，44，14： | 21 |
| 2 | Hyperthermic intraperitoneal chemotherapy for gastric cancer with peritoneal metastasis:A multicenter propensity scorematched cohort study显示文摘Objective:Systemic chemotherapy has limited efficacy in the treatment of peritoneal metastasis(PM)in gastric cancer(GC).Hyperthermic intraperitoneal chemotherapy(HIPEC)combined with complete cytoreductive surgery(CRS)has shown promising outcomes but remains controversial.The present study aimed to evaluate the safety and efficacy of HIPEC without CRS in GC patients with PM.Methods:This retrospective propensity score-matched multicenter cohort study included GC patients with PM treated with either chemotherapy alone(Cx group)or with HIPEC combined with chemotherapy(HIPEC-Cx group)in four Chinese high-volume gastric medical centers between 2010 and 2017.The primary outcomes were median survival time(MST)and 3-year overall survival(OS).Propensity score matching was performed to compensate for controlling potential confounding effects and selection bias.Results:Of 663 eligible patients,498 were matched.The MST in the Cx and HIPEC-Cx groups was 10.8 and 15.9 months,respectively[hazard ratio(HR)=0.71,95%confidence interval(95%CI),0.58-0.88;P=0.002].The 3-year OS rate was 10.1%(95%CI,5.4%-14.8%)and 18.4%(95%CI,12.3%-24.5%)in the Cx and HIPEC-Cx groups,respectively(P=0.017).The complication rates were comparable.The time to first flatus and length of hospital stay for patients undergoing HIPEC combined with chemotherapy was longer than that of chemotherapy alone(4.6±2.4 d vs.2.7±1.8 d,P<0.001;14.2±5.8 d vs.11.4±7.7 d,P<0.001),respectively.The median follow-up period was 33.2 months.Conclusions:Compared with standard systemic chemotherapy,HIPEC combined with chemotherapy revealed a statistically significant survival benefit for GC patients with PM,without compromising patient safety. | Ziying Lei Jiahong Wang Zhi Li Baozhong Li Jiali Luo Xuejun Wang Jin Wang MingchenBa Hongsheng Tang Qingjun He Quanxing Liao Xiansheng Yang Tianpei Guan Han Liang Shuzhong Cui | 2020 | Chinese Journal of Cancer Research2020，32，6： | 11 |
| 3 | Relationship between Mesozoic Magmatism and Subduction in the Da Hinggan-Yanshan Area显示文摘High-resolution tomographic images of the belt crossing the Japan Trench-Changbai Mountains-Dong Ujimqin Qi are represented in this paper, revealing the shape of a subducted slab in the western Pacific region and characteristics of the lithospheric structures under the Changbai Mountains and the Da Hinggan Mountains. Studies of the spatial distribution, subduction time and the time-lag between the subduction and magmatism, combined with petrology and isotope geochemistry of the Late Mesozoic volcano-plutonic rocks from the Da Hinggan Mountains-Yanshan Mountains have further proved the independence of magmatic activities from the subduction of the Pacific plate. The Mesozoic tectono-thermal evolutionary history and structural characteristics of the lithosphere in the Da Hinggan Mountains and North China suggest that the formation and evolution of magma have probably a close relationship with the delamination and thinning of the continental lithosphere and the underplating resulting from the consequent upwelling of the asthenosphere. On the other hand, the large-scale strike-slip fault system, resulting from sinistral shearing of the Pacific plate relative to the Asian continent in the Mesozoic, is responsible for the formation and emplacement of magma on the continental margin. It was the intense crust-mantle interaction, together with structural deformation at the shallower levels that led to the large tectono-magmatic belt in the East Asian continental margin. | SHAO Ji'an LIU Futian CHEN Hui HAN Qingjun | 2001 | Acta Geologica Sinica(English Edition)2001，75，1： | 9 |
| 4 | Sulfate sources constrained by sulfur and oxygen isotopic compositions in the upper reaches of the Xijiang River,China显示文摘While it is critical to accurately understand the sources and transformation of sulfate based on time-series analysis, there are limited studies on temporal variation of sulfate in rivers and on rock weathering by sulfuric acids.We conducted a monthly sampling campaign in the Beipan, Nanpan, and Hongshui Rivers over the course of one hydrological year. This study examined seasonal variations in riverine sulfate impacted by the monsoon climate in the upper reaches of the Xijiang River basin. In general, the SO_4^(2-) contents in these rivers dropped from relatively high levels to low values during the high-flow season, in response to increasing discharge. The sulfate was generally enriched in heavy isotopes during the low-flow season compared to the high-flow season. The calculated results indicate that the riverine sulfate was mainly derived from sulfide oxidation, but that evaporite dissolution could be an important source during the low-flow season, based on isotopic evidence. Mine drainage is likely an important source of sulfate to these rivers during the high-flow season due to contributions from fast surface flow, which responds to frequent heavy rain in monsoonal climate regions. Arelatively high proportion of HCO_3^- was found to be derived from rock weathering by sulfuric acid during the high-flow season when compared to that observed during the low-flow season. The results suggest that approximately one quarter of the HCO_3^- in the Hongshui River originated from carbonate weathering by sulfuric acid derived from the oxidation of sulfide. Such information on the specific dual isotopic characteristics of riverine sulfate throughout a hydrological year can provide unique evidence for understanding the temporal variability of sulfate concentrations and weathering processes in rivers. | Jing Liu Siliang Li Jun Zhong Xuetao Zhu Qingjun Guo Yunchao Lang Xiaokun Han | 2017 | Acta Geochimica2017，36，4： | 2 |
| 5 | Single-dose AAV-based vaccine induces a high level of neutralizing antibodies against SARS-CoV-2 in rhesus macaques显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)is a highly infectious respiratory disease that continues to pose a serious global public health emergency.The disease shows a high infection rate,long incubation period,and rapidly emerging variants,which have led to its rapid spread worldwide(Krammer 2020).Many vaccines have been developed for the control of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the virus responsible for COVID-19,including vaccines based on messenger RNA(mRNA)(Polack et al.2020),viral vectors(Zhu et al.2020),recombinant proteins(Yang et al.2020),and inactivated SARS-CoV-2(Zhang et al.2021). | Dali Tong Mei Zhang Yunru Yang Han Xia Haiyang Tong Huajun Zhang Weihong Zeng Muziying Liu Yan Wu Huan Ma Xue Hu Weiyong Liu Yuan Cai Yanfeng Yao Yichuan Yao Kunpeng Liu Shifang Shan Yajuan Li Ge Gao Weiwei Guo Yun Peng Shaohong Chen Juhong Rao Jiaxuan Zhao Juan Min Qingjun Zhu Yanmin Zheng Lianxin Liu Chao Shan Kai Zhong Zilong Qiu Tengchuan Jin Sandra Chiu Zhiming Yuan Tian Xue | 2023 | Protein & Cell2023，14，1： | 0 |
| 6 | Existence of Ground States for Fractional Kirchhoff Equations显示文摘In this paper, we study a fractional Kirchhoff problem and establish the existence of nontrivial nonnegative ground states under some suitable conditions. | Qingjun LOU Zhiqing HAN | 2018 | Journal of Mathematical Research with Applications2018，38，6： | 0 |
| 7 | A unique photosystem I reaction center from a chlorophyll d-containing cyanobacterium Acaryochloris marina显示文摘Photosystem I(PSI)is a large protein supercomplex that catalyzes the light-dependent oxidation of plastocyanin(or cytochrome c6)and the reduction of ferredoxin.This catalytic reaction is realized by a transmembrane electron transfer chain consisting of primary electron donor(a special chlorophyll(Chl)pair)and electron acceptors A_(0),A_(1),and three Fe_(4)S_(4) clusters,F_(X),F_(A),and F_(B).Here we report the PSI structure from a Chl d-dominated cyanobacterium Acaryochloris marina at 3.3Åresolution obtained by single-particle cryo-electron microscopy.The A.marina PSI exists as a trimer with three identical monomers.Surprisingly,the structure reveals a unique composition of electron transfer chain in which the primary electron acceptor A_(0) is composed of two pheophytin a rather than Chl a found in any other well-known PSI structures.A novel subunit Psa27 is observed in the A.marina PSI structure.In addition,77 Chls,13α-carotenes,two phylloquinones,three Fe-S clusters,two phosphatidyl glycerols,and one monogalactosyl-diglyceride were identified in each PSI monomer.Our results provide a structural basis for deciphering the mechanism of photosynthesis in a PSI complex with Chl d as the dominating pigments and absorbing far-red light. | Caihuang Xu Qingjun Zhu Jing-Hua Chen Liangliang Shen Xiaohan Yi Zihui Huang Wenda Wang Min Chen Tingyun Kuang Jian-Ren Shen Xing Zhang Guangye Han | 2021 | Journal of Integrative Plant Biology2021，63，10： | 0 |
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