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| 1 | Hyperbaric oxygen therapy improves cognitive functioning after brain injury显示文摘Hyperbaric oxygen therapy has been widely applied and recognized in the treatment of brain injury;however,the correlation between the protective effect of hyperbaric oxygen therapy and changes of metabolites in the brain remains unclear.To investigate the effect and potential mechanism of hyperbaric oxygen therapy on cognitive functioning in rats,we established traumatic brain injury models using Feeney’s free falling method.We treated rat models with hyperbaric oxygen therapy at 0.2 MPa for 60 minutes per day.The Morris water maze test for spatial navigation showed that the average escape latency was significantly prolonged and cognitive function decreased in rats with brain injury.After treatment with hyperbaric oxygen therapy for 1 and 2 weeks,the rats’spatial learning and memory abilities were improved.Hydrogen proton magnetic resonance spectroscopy analysis showed that the N-acetylaspartate/creatine ratio in the hippocampal CA3 region was significantly increased at 1 week,and the N-acetylaspartate/choline ratio was significantly increased at2 weeks after hyperbaric oxygen therapy.Nissl staining and immunohistochemical staining showed that the number of nerve cells and Nissl bodies in the hippocampal CA3 region was significantly increased,and glial fibrillary acidic protein positive cells were decreased after a 2-week hyperbaric oxygen therapy treatment.Our findings indicate that hyperbaric oxygen therapy significantly improves cognitive functioning in rats with traumatic brain injury,and the potential mechanism is mediated by metabolic changes and nerve cell restoration in the hippocampal CA3 region. | Su Liu Guangyu Shen Shukun Deng Xiubin Wang Qinfeng Wu Aisong Guo | 2013 | Neural Regeneration Research2013，8，35： | 16 |
| 2 | Optimization of Stocking Density for the Sea Cucumber, Apostichopus japonicus Selenka, Under Feed-Supplement and Non-Feed-Supplement Regimes in Pond Culture显示文摘Optimal stocking densities were investigated for the sea cucumber Apostichopus japonicus Selenka under feed-supplement and non-feed-supplement regimes in net enclosures for 333 d. Substantial weight loss occurred during the aestivation phase (AE). Decreased growth rates were also observed during the winter phase (WT). In contrast, sea cucumbers showed rapid growth during the spring (SP) and autumn (AU) phases. Feeding regimes considerably influenced the growth performance, i.e., sea cucumbers grew faster under feed-supplement regime than under non-feed-supplement regime (P < 0.05). The average survival rates of sea cucumbers under feed-supplement regime were higher than those under non-feed-supplement regime for both the autumn phase and spring phase, but the differences were only significant for the latter phase (P < 0.05). The fitted B-N curves showed that the optimal stocking densities, in terms of net production, were 22.3 ind. m-2 for feed-supplement regime and 14.1 ind. m-2 for non-feed-supplement regime. | QIN Chuanxin DONG Shuanglin TAN Fuyi TIAN Xiangli WANG Fang DONG Yunwei GAO Qinfeng | 2009 | Journal of Ocean University of China2009，8，3： | 10 |
| 3 | Seasonal Changes in Food Uptake by the Sea Cucumber Apostichopus japonicus in a Farm Pond: Evidence from C and N Stable Isotopes显示文摘This study investigated the seasonal changes in carbon (C) and nitrogen (N) stable isotope values of several typical food sources of Apostichopus japonicus in a farm pond, including particulate organic matter (POM), macroalgae, benthic microalgae and animals such as nematode and copepod. The stable isotope technique was used to quantify relative contributions of various sources to the food uptake by A. japonicus. The results showed that significant changes occurred in the C and N stable isotope values of sea cucumber food sources due to the seasonality of micro-or macroalgae prosperity and the fluctuation of environmental conditions. The sea cucumber A. japonicus exhibited corresponding alterations in feeding strategy in response to the changes in food conditions. Calculation with a stable isotope mixing model showed that macroalgae was the principal food source for A. japonicus throughout the 1-yr investigation, with the relative contribution averaging 28.1% - 63.2%. The relative contributions of other food sources such as copepod and nematode, POM, benthic microalgae to the total food uptake by sea cucumber averaged 22.6% - 39.1%, 6.3% - 22.2%, 2.8% - 6.5%, and 2.8% - 4.2%, respectively. Together these results indicated that the seasonal changes in food sources led to the obvious temporal differences in the relative contribution of various food sources utilized by A. japonicus. Such findings provide the basic scientific information for improving the aquaculture techniques of A. japonicus, particularly for optimizing the food environment of A. japonicus culture in farm ponds. | SUN Zhenlong GAO Qinfeng DONG Shuanglin Paul K. S. Shin WANG Fang | 2013 | Journal of Ocean University of China2013，12，1： | 9 |
| 4 | m6A demethylase FTO attenuates cardiac dysfunction by regulating glucose uptake and glycolysis in mice with pressure overload-induced heart failure显示文摘Dear Editor,N6-methyladenosine(m6A)is the most common posttranscriptional mammalian mRNA modification involved in multiple biological processes and diseases.1 However,its role in cardiac energy metabolism changes during heart failure(HF)remains elusive.Here we explored the role of m6A demethylase fat mass and obesity-associated protein(FTO)in glucose metabolism during pressure overload-induced HF.Methylated RNA immunoprecipitation sequencing(MeRIP-seq)was performed to map transcriptome-wide m6A modifications in transverse aortic constriction(TAC)and sham hearts.The number of identified m6A peaks was higher in the TAC than in the sham hearts(Fig.1a).Consistent with previous reports,the m6A peaks were enriched in 3’-untranslated regions in both the TAC and sham hearts(Fig.1b).2 The m6A peaks were characterized by the canonical RGAAR(R=A or G)motif(Fig.1c). | Beijian Zhang Hao Jiang Jian Wu Yun Cai Zhen Dong Yongchao Zhao Qinfeng Hu Kai Hu Aijun Sun Junbo Ge | 2021 | Signal Transduction and Targeted Therapy2021，6，12： | 6 |
| 5 | Influence of torrefaction pretreatment on biomass gasification technology显示文摘Torrefaction is a slow pyrolysis process that is carried out in the relatively low temperature range of 220-300°C.The influence of torrefaction as a pretreatment on biomass gasification technology was investigated using a bench-scale torrefaction unit,a bench-scale laminar entrained-flow gasifier,and the analysis techniques TGA-FTIR and low temperature nitrogen adsorption.A series of experiments were performed to examine the characteristics of the torrefaction process,the properties of torrefaction products,and the effects of torrefaction on gas composition,cold gas efficiency and gasification efficiency.The results showed that during the torrefaction process the moisture content of biomass were reduced,and the wood fiber structure of the material was destroyed.This was beneficial to storage,transport and subsequent treatments of biomass in large scale.For solid products,torrefaction increased the energy density,decreased the oxygen/carbon ratio,and created a more complex pore structure.These improved the syngas quality and cold gas efficiency.Combustible gases accounted for about 50% of non-condensable gaseous torrefaction products.Effective use of the torrefaction gases can save energy and improve efficiency.Overall,biomass torrefaction technology has good application prospects in gasification processes. | CHEN Qing ZHOU JinSong LIU BingJun MEI QinFeng LUO ZhongYang | 2011 | Chinese Science Bulletin2011，56，14： | 6 |
| 6 | Statistical Inference for Partially Linear Regression Models with Measurement Errors显示文摘在这篇论文,作者为某 covariates 与错误被测量的部分线性的回归模型调查统计推理的三个方面。第一,一个带宽选择过程被建议,它是基于差别的技术的联合;GCV 方法。第二,一个 goodness-of-fit 测试过程被建议,它是概括可能性技术的延期。第三,为参量的部分的一个可变选择过程被提供基于非凹面 penalization;改正的侧面最不摆平。作为一样“可变选择经由非,凹面惩罚了可能性;它的神谕性质“(J。Amer。统计员。Assoc, 96, 2001, 1348 1360 ) ,产生评估者与规则化参数的一种合适的选择有一个神谕性质,这被显示出;惩罚功能。模拟研究被进行说明建议过程的有限样品表演。 | Jinhong YOU Qinfeng XU Bin ZHOU | 2008 | Chinese Annals of Mathematics,Series B2008，29，2： | 6 |
| 7 | Individual Variation in Growth in Sea Cucumber Apostichopus japonicus(Selenck) Housed Individually显示文摘The exceptionally large individual growth variation has been previously recognized in several sea cucumber cohorts.However,there is a lack of information regarding the mechanism of such individual differences.In this study,the sea cucumber Apostichopus japonicus(Selenka) was reared individually in order to eliminate possible effects of social interaction,stocking density,etc.The results showed that there were substantial differences in growth among the sea cucumber individuals during the 100-day experiment.The special growth rate of the sea cucumber individuals differed by up to three folds(from 0.40% to 1.01%),and the coefficient of variation in body weight increased from 12.04% to 40.51%.The final wet body weight,food intake and food conversion efficiency for each sea cucumber were generally positively correlated with their initial wet body weight(P<0.05).Energy budget of the animals showed that the food energy spent on respiration was much greater(about four folds) but energy deposited for growth was much less for(initially) smaller than for larger A.japonicus.The present result implies that there are obvious genetic differences among the sea cucumber individuals,largely accounting for the individual growth variation of the cohort sea cucumber.These results will provide some basic data for promoting selective breeding and farming of the sea cucumber. | LIANG Miao DONG Shuanglin GAO Qinfeng WANG Fang TIAN Xiangli | 2010 | Journal of Ocean University of China2010，9，3： | 5 |
| 8 | Effects of wing flexibility on aerodynamic performance of an aircraft model显示文摘The low-speed wind tunnel experiment is carried out on a simplified aircraft model to explore the influence of wing flexibility on the aircraft aerodynamic performance.The investigation involves the measurements of force,membrane deformation and velocity field at Reynolds number of 5.4×10^(4)-1.1×10^(5).In the lift curves,two peaks are observed.The first peak,corresponding to the stall,is sensitive to the wing flexibility much more than the second peak,which nearly keeps constant.For the optimal case,in comparison with the rigid wing model,the delayed stall of nearly5°is achieved,and the relative lift increment is about 90%.It is revealed that the lift enhanced region corresponds to the larger deformation and stronger vibration,which leads to stronger flow mixing near the flexible wing surface.Thereby,the leading-edge separation is suppressed,and the aerodynamic performance is improved significantly.Furthermore,the effects of sweep angle and Reynolds number on the aerodynamic characteristics of flexible wing are also presented. | Qinfeng GUO Xi HE Zhuo WANG Jinjun WANG | 2021 | Chinese Journal of Aeronautics2021，34，9： | 4 |
| 9 | 生物多样性的干扰、生活史及优化管理显示文摘在许多生态系统中,日益增长的人类活动已经加剧了干扰的频度和强度。结果,在地球上,短命物种(包括许多外来的物种)在丰富度上可能会有巨大的提高;同时长寿命的物种又可能消失。这个结论可以通过对理论和经验研究中大量演替循环的观察得到。这篇文章主要讨论现有生态管理政策和保护中两个受到忽视的问题:①生活史的限制因素;③未来全球变暖趋势。同时也强调了这两个因素在平衡干扰的频度和强度以优化生物多样性保持和生态系统管理方面的重要性。 | Qinfeng Guo 伍建榕 | 2003 | AMBIO-人类环境杂志2003，32，6： | 4 |
| 10 | A study of specific interaction of the transcription factor and the DNA element by atomic force microscopy显示文摘Atomic force microscopy (AFM) was employed to quantitatively detect the interaction between a transcription factor, ZmDREBIA, and its target DNA sequence (DRE).The specificity of the interaction was revealed by comparing the binding probability of ZmDREBIA to DRE element with core sequence ACCGAC and to the ERE element with core sequence AGCCGCC. Moreover, the single-molecular unbinding force between ZmDREBIA and DRE element was determined using Poisson statistical method to be 99±9 pN.The results indicated that AFM could serve as a sensitive and reliable technique to probe the interaction properties of the transcription factor and DNA element at single-molecular level, thus indicating that AFM is advantageous over the traditional methods, such as the electrophoretic mobility shift assay, regarding to the functional analysis of transcription factors. | QINFeng JIANGYaxin MAXinyong CHENFeng FANGXiaohong BAIChunli LIYiqin | 2004 | Chinese Science Bulletin2004，49，13： | 4 |
| 11 | DNA Barcoding and Mini-DNA Barcoding Reveal Mislabeling of Salmonids in Different Distribution Channels in the Qingdao Area显示文摘There is an increasing demand for salmonid authentication due to the globalization of the salmonid trade.DNA barcoding and mini-DNA barcoding are widely used for identifying fish species based on a fragment of the mitochondrial cytochrome c oxidase subunit I(COI)sequence.In this study,rainbow trout(Oncorhynchus mykiss),steelhead trout(O.mykiss),and Atlantic salmon(Salmo salar)collected from two salmonid aquaculture bases in China were authenticated by DNA barcoding(about 650 bp)and mini-DNA barcoding(127 bp)to evaluate the accuracy of the two methods in the identification of different salmonid species.The results revealed that both methods could effectively distinguish O.mykiss and S.salar with 100%accuracy.However,the two methods failed to separate rainbow trout(O.mykiss)and steelhead trout(O.mykiss),which are the same species but cultured in different water environments.Moreover,salmonid samples from three main distribution channels in the Qingdao area(traditional supermarkets,online supermarkets,and sushi bars)were identified by the two methods.Substitution of S.salar with O.mykiss was discovered,and the 27.78%overall substitution rate of salmonids in the Qingdao area was higher than those in other regions reported in previous studies.In addition,the mislabeling rates of salmonids from traditional supermarkets,online supermarkets,and sushi bars were compared in this study.The mislabeling rate was significantly greater in sushi bars(50%)than in the other two channels(16.67%),suggesting that stronger monitoring and enforcement measures are necessary for the aquatic food catering industry. | HAN Cui DONG Shuanglin LI Li GAO Qinfeng ZHOU Yangen | 2021 | Journal of Ocean University of China2021，20，6： | 3 |
| 12 | Protective electrode/electrolyte interphases for high energy lithium-ion batteries with p-toluenesulfonyl fluoride electrolyte additive显示文摘High energy density lithium-ion batteries using Ni-rich cathode(such as LiNi0.6Co0.2Mn0.2O2) suffer from severe capacity decay.P-toluenesulfonyl fluoride(pTSF) has been investigated as a novel film-forming electrolyte additive to enhance the cycling performances of graphite/LiNi0.6Co0.2Mn0.2O2 pouch cell.In comparison with the baseline electrolyte,a small dose of pTSF can significantly improve the cyclic stability of the cell.Theoretical calculations together with experimental results indicate that pTSF would be oxidized and reduced to construct protective interphase film on the surfaces of LiNi0.6Co0.2Mn0.2O2 cathode and graphite anode,respectively.These S-containing surface films derived from pTSF effectively mitigate the decomposition of electrolyte,reduce the interphasial impedance,as well as prevent the dissolution of transition metal ions from Ni-rich cathode upon cycling at high voltage.This finding is beneficial for the practical application of high energy density graphite/LiNi0.6Co0.2Mn0.2O2 cells. | Yanxia Che Xiuyi Lin Lidan Xing Xiongcong Guan Rude Guo Guangyuan Lan Qinfeng Zheng Wenguang Zhang Weishan Li | 2021 | Journal of Energy Chemistry2021，30，1： | 3 |
| 13 | Sustainability Evaluation of Different Systems for Sea Cucumber(Apostichopus japonicus) Farming Based on Emergy Theory显示文摘Emergy analysis is effective for analyzing ecological economic systems. However, the accuracy of the approach is affected by the diversity of economic level, meteorological and hydrological parameters in different regions. The present study evaluated the economic benefits, environmental impact, and sustainability of indoor, semi-intensive and extensive farming systems of sea cucumber(Apostichopus japonicus) in the same region. The results showed that A. japonicus indoor farming system was high in input and output(yield) whereas pond extensive farming system was low in input and output. The output/input ratio of indoor farming system was lower than that of pond extensive farming system, and the output/input ratio of semi-intensive farming system fell in between them. The environmental loading ratio of A. japonicus extensive farming system was lower than that of indoor farming system. In addition, the emergy yield and emergy exchange ratios, and emergy sustainability and emergy indexes for sustainable development were higher in extensive farming system than those in indoor farming system. These results indicated that the current extensive farming system exerted fewer negative influences on the environment, made more efficient use of available resources, and met more sustainable development requirements than the indoor farming system. A. japonicus farming systems showed more emergy benefits than fish farming systems. The pond farming systems of A. japonicus exploited more free local environmental resources for production, caused less potential pressure on the local environment, and achieved higher sustainability than indoor farming system. | WANG Guodong DONG Shuanglin TIAN Xiangli GAO Qinfeng WANG Fang | 2015 | Journal of Ocean University of China2015，14，3： | 2 |
| 14 | Reactive Inorganic Vapor Deposition of Perovskite Oxynitride Films for Solar Energy Conversion显示文摘The synthesis of perovskite oxynitrides,which are promising photoanode candidates for solar energy conversion,is normally accomplished by high-temperature ammonolysis of oxides and carbonate precursors,thus making the deposition of their planar films onto conductive substrates challenging.Here,we proposed a facile strategy to prepare a series of perovskite oxynitride films.Taking SrTaO_(2)N as a prototype,we prepared SrTaO_(2)N films on Ta foils under NH_(3) flow by utilizing the vaporized SrCl_(2)/SrCO_(3) eutectic salt.The SrTaO_(2)N films exhibit solar water-splitting photocurrents of 3.0 mA cm^(-2) at 1.23 V vs.RHE(reversible hydrogen electrode),which increases by 270%compared to the highest photocurrent(1.1 mA cm^(-2) at 1.23 V vs.RHE)of SrTaO_(2)N reported in the literature.This strategy may also be applied to directly prepare a series of perovskite oxynitride films on conductive substrates such as ATaO_(2)N(A=Ca,Ba)and ANbO_(2)N(A=Sr,Ba). | Tao Fang Huiting Huang Jianyong Feng Yingfei Hu Qinfeng Qian Shicheng Yan Zhentao Yu Zhaosheng Li Zhigang Zou | 2019 | Research2019，，1： | 2 |
| 15 | On strong Markov property for Fleming-Viot processes显示文摘In this note,we prove that any Fleming-Viot process on a Polish space is strongly Markovian provided so is the mutation process. | LI QinFeng MA ChunHua XIANG KaiNan | 2013 | Science China Mathematics2013，56，10： | 2 |
| 16 | Effects of sleep deprivation on polysomnography and executive function in patients with depression显示文摘 | Lu Yingzhi Ren Qingtao Zong Li Wu Yingli Zhang Qinfeng Ma Xiuqing Pu Jinyu Dong Hanzhen Liu Qingqing Tang Yunxiang Song Lisheng Chen Xingshi Pan Xiao Cui Yi | 2014 | Chinese Medical Journal2014，，18： | 2 |
| 17 | Preconditioning with Hyperbaric Oxygen Induces Tolerance Against Renal Ischemia-Reperfusion Injury Via Increased Expression of Heme Oxygenase-1显示文摘 | Xiaozhou He Xianlin Xu Min Fan Xiao Chen Xuejun Sun Guanghua Luo Lujun Chen Qinfeng Mu Yuehua Feng Qingyan Mao Zhifu Chao | 2011 | Journal of Surgical Research2011，，2： | 2 |
| 18 | Nitrogen and Phosphorus Budget of a Polyculture System of Sea Cucumber(Apostichopus japonicus), Jellyfish(Rhopilema esculenta) and Shrimp(Fenneropenaeus chinensis)显示文摘The nitrogen(N) and phosphorus(P) budget and the ecological efficiency of a polyculture system of sea cucumber(Apostichopus japonicus), jellyfish(Rhopilema esculenta) and shrimp(Fenneropenaeus chinensis) were studied in a cofferdam, 120.2 ha in size. The nutrients were supplied by spring tide inflow. In total, 139600 kg N yr-1 and 9730 kg P yr-1 input to the system; while 118900 kg N yr-1 and 2840 kg P yr-1 outflowed from the system concurrently, thus the outflow was 85.7%(N) and 29.2%(P) of inflow. The production of N and P was 889.5 kg yr-1 and 49.28 kg yr-1(sea cucumber) and 204 kg yr-1 and 18.03 kg yr-1(jellyfish and shrimp), respectively. The utilization rate of N and P by polycultured animals was 7.8‰ and 6.9‰, respectively, 21.9% and 38% higher than that of monocultured sea cucumber. Our results indicated that the polyculture system was an efficient culture system of animals and a remediation system of coastal environment as well; it scavenged 14.3% and 70.8% of N and P, respectively. Such an ecological efficiency may be improved further by increasing either the stocking density or the size of sea cucumber or both. | LI Junwei DONG Shuanglin GAO Qinfeng ZHU Changbo | 2014 | Journal of Ocean University of China2014，13，3： | 2 |
| 19 | Distribution of HCN, NH3 ,NO and N2 in an entrained flow gasifier显示文摘 | Chen Zhong Yuan Shuai Liang Qinfeng | 2009 | Chemical Engineering Journal2009，148，： | 1 |
| 20 | In situ observation of the effects of local irradiation on cytotoxic and regulatory T lymphocytes in cervical cancer tissue显示文摘 | Qinfeng S Depu W Xiaofeng Y | 2013 | Radiat Res2013，179，5： | 1 |
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