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| 1 | Four 14(13→12)‑Abeolanostane Triterpenoids with 6/6/5/6‑Fused Ring System from the Roots of Kadsura coccinea显示文摘Four new rearranged 6/6/5/6-fused lanostane-type triterpenoids,kadcoccitanes A-D(1-4),were isolated from the roots of Kadsura coccinea,and their structures were mainly elucidated by comprehensive analysis of their spectroscopic data.Additionally,the structure of 1 was ambiguously verifed by single-crystal X-ray difraction,while the structure of 2,which features a novel 8,16-epoxy motif,was validated by quantum chemical calculation of NMR parameters and ECD spectrum.Moreover,1 and 4 were found to exhibited anticoagulant activity,while 3 and 4 were found to possess anti-platelet aggregation activity. | Hou-Chao Xu Kun Hu Han-Dong Sun Pema-Tenzin Puno | 2019 | Natural Products and Bioprospecting2019，9，3： | 4 |
| 2 | Secondary Metabolites from the Endophytic Fungus Xylaria sp.hg1009显示文摘A detailed chemical investigation of the secondary metabolites produced by the endophytic fungus Xylaria sp.isolated from the stems of Isodon sculponeatus afforded six new compounds,xylariahgins A-F(1-6),two new natural products(7 and 8),along with two known compounds(9 and 10)(Fig.1).The structures of all compounds were unambiguously established by analyzing their spectroscopic data or referring to pertinent literature.Compounds 1-8 were tested for their cytotoxic activity against five human tumor cell lines. | Rong Chen Jian-Wei Tang Xing-Ren Li Miao Liu Wen-Ping Ding Yuan-Fei Zhou Wei-Guang Wang Xue Du Han-Dong Sun Pema-Tenzin Puno | 2018 | Natural Products and Bioprospecting2018，8，2： | 2 |
| 3 | Analysis of the primary and compensatory curvatures following Zielk instrumentation for idiopathic scoliosis显示文摘 | Johnson JR Ostermann PA | 1989 | Spine1989，14，： | 1 |
| 4 | Functional outcome of patients with salvageable limbs with grades Ⅲ-B and Ⅲ-C open fractures of the tibia显示文摘 | Puno RM Grossfeld SL Henry SL | 1996 | Microsurgery1996，17，3： | 1 |
| 5 | Functional outcome of patients with salvageable limbs with grades ⅢB and ⅢC open fractures of the tibia显示文摘 | Puno RM Grossfeld SL Henry SL | 1996 | Microsurgery1996，17，： | 1 |
| 6 | Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signaling pathways: novel insights into vis- fatin-induced angiogenesis 显示文摘 | Adya R Tan BK Puno A | 2008 | Cardiovasc Res2008，78，2： | 1 |
| 7 | Postoperative respiratory complicati-ons innon-idiopathic scoliosis显示文摘 | Anderson PR Puno MR Lovell SL | 1985 | Aeta Anaesthesiol Seand1985，2，9： | 1 |
| 8 | Salvage of instrumen- tal lumbar fusions complicated by surgical wound infection 显示文摘 | Glassman SD Dimar JR Puno RM | 1996 | Spine ( Phila Pa 1976)1996，21，18： | 1 |
| 9 | Treatment recommenda-tions for idiopathic scoliosis: an assessment of the Lenkeclassification显示文摘 | Puno RM An KC Puno RL | 2003 | Spine2003，28，18： | 1 |
| 10 | Perioperative complications of posterior lumbar clecompression and arthrodesis in older adults 显示文摘 | Carreon LY Puno RM Dimar JR el al | 2003 | J Bone Joint Surg Am2003，85，11： | 1 |
| 11 | Treatment recommendations for idiopathic scoliosis:an assessment of the Lenke classification显示文摘 | Puno RM An KC Puno RL | 2003 | Spine2003，28，18： | 1 |
| 12 | Functional outcome of patients with salvageable limbs with grades I]-B and III-C open fractures of the tibia显示文摘 | Puno RM Grossfeld SL Henry SL | 1996 | Microsurgery1996，17，3： | 1 |
| 13 | Critical analysis of results of treatment of 201 tibial shaft fracture显示文摘 | Puno RM Teynor JT Nagano J | 1986 | Clin Orthop1986，212，5： | 1 |
| 14 | Functional outcome of patients with salvageable limbs with grades Ⅲ-B and Ⅲ-C open fractures of the tibia显示文摘 | Puno RM Grossfeld SL Henry SL | 1996 | Microsurgery1996，17，3： | 1 |
| 15 | Treatment recommendations for idiopathic scoliosis:an assessment of the Lenke classification显示文摘 | Puno RM An KC Puno RL | | 0，，1976： | 1 |
| 16 | Postoperative respiratory complications in non-idiopathic scoliosis 显示文摘 | Anderson PR Puno MR Lovell SL | 1985 | Acta Anaesthesiol Scand1985，29，2： | 1 |
| 17 | Non-neurologic complications following surgery for adolescent idiopathic scoliosis显示文摘 | Carreon LY Puno RM Lenke LG | 2007 | J Bone Joint Surg Am2007，89，11： | 1 |
| 18 | Pestaloamides A and B,two spiro-heterocyclic alkaloid epimers from the plant endophytic fungus Pestalotiopsis sp.HS30显示文摘Pestaloamides A and B(1 and 2),two novel alkaloids featuring an unprecedented spiro[imidazothiazoledione-alkylidenecyclopentenone]scaffold,were obtained from the cultures of an endophytic fungus Pestalotiopsis sp.HS30 which inhabited the stems of Isodon xerophilus.Their planar structures and absolute configurations were fully determined by extensive spectroscopic analysis and X-ray crystallography.In addition,both compounds 1 and 2 showed the latent tumor immunotherapy activity through markedly promoting the cell surface engagement of NKG2 D ligands involving MICA/B and ULBP1 in HCT116 cells. | Xiao-Zheng Su Yi-Ying Zhu Jian-Wei Tang Kun Hu Xiao-Nian Li Han-Dong Sun Yan Li Pema-Tenzin Puno | 2020 | Science China Chemistry2020，63，9： | 1 |
| 19 | Visfatin induces human endothelinl VEGF andMMP-2/9 production viaMAPK and PI3K/Akt signalling path ways:novel insights into visfatin-induced angiogenesis显示文摘 | Adya R Tan BK Puno A | 2008 | Cadiovasc Res2008，78，2： | 1 |
| 20 | Long-term effects of tibi-al angular malunion on the knee and ankle joints显示文摘 | Puno R M Vaughan J J Stetten M L | 1991 | J Orthop Trau-ma1991，5，3： | 1 |
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