|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Long-term outcome and prognostic factors of patients with hilar cholangiocarcinoma显示文摘AIM: To evaluate the long-term outcome and prognostic factors of patients with hilar cholangiocarinoma. METHODS: Ninety-six consecutive patients underwent treatment for malignant hilar bile duct tumors during 1995–2005. Of the 96 patients, 20 were initially treated with surgery (n = 2 R0 / n = 18 R1). In non-operated patients, data analysis was performed retrospectively. RESULTS: Among the 96 patients, 76 were treated with endoscopic transpapillary (ERC, n = 45) and/or percutaneous transhepatic biliary drainage (PTBD, n = 31). The mean survival time of these 76 patients undergoing palliative endoscopic and/or percutaneous drainage was 359 ± 296 d. The mean survival time of patients with initial bilirubin levels > 10 mg/dL was significantly lower (P < 0.001) than patients with bilirubin levels < 10 mg/dL. The mean survival time of patients with Bismuth stage Ⅱ (n = 8), Ⅲ (n = 28) and Ⅳ (n = 40) was 496 ± 300 d, 441 ± 385 d and 274 ± 218 d, respectively. Thus, patients with advanced Bismuth stage showed a reduced mean survival time, but the difference was not significant. The type of biliary drainage had no significant beneficial effect on the mean survival time (ERC vs PTBD, P = 0.806). CONCLUSION: Initial bilirubin level is a significant prognostic factor for survival of patients. In contrast, age, tumor stage according to the Bismuth-Corlette classification, and types of intervention are not significant prognostic parameters for survival. Palliative treatment with endoscopic or percutaneous biliary drainage is still suboptimal, new diagnostic and therapeutic tools need to be evaluated. | Andreas Weber Sonja Landrock Jochen Schneider Manfred Stangl Bruno Neu Peter Born Meinhard Classen Thomas Rsch Roland M Schmid Christian Prinz | 2007 | World Journal of Gastroenterology2007，13，9： | 23 |
| 2 | Late biliary complications in human alveolar echinococcosis are associated with high mortality显示文摘AIM:To evaluate the incidence of late biliary complications in non-resectable alveolar echinococcosis(AE)under long-term chemotherapy with benzimidazoles.METHODS:Retrospective analysis of AE patients with biliary complications occurring more than three years after the diagnosis of AE.We compared characteristics of patients with and without biliary complications,analyzed potential risk factor for biliary complications and performed survival analyses.RESULTS:Ninety four of 148 patients with AE in Zurich had non-resectable AE requiring long-term benzimidazole chemotherapy,of which 26(28%)patients developed late biliary complications.These patients had a median age of 55.5(35.5-65)years at diagnosis of AE and developed biliary complications after 15(8.25-19)years of chemotherapy.The most common biliary complications during long-term chemotherapy were late-onset cholangitis(n=14),sclerosing cholangitis-like lesions(n=8),hepatolithiasis(n=5),affection of the common bile duct(n=7)and secondary biliary cirrhosis(n=7).Thirteen of the 26 patients had undergone surgery(including 12 resections)before chemotherapy.Previous surgery was a risk factor for late biliary complications in linear regression analysis(P=0.012).CONCLUSION:Late biliary complications can be observed in nearly one third of patients with non-resectable AE,with previous surgery being a potential risk factor.After the occurrence of late biliary complications,the median survival is only 3 years,suggesting that late biliary complications indicate a poor prognostic outcome. | Pascal Frei Benjamin Misselwitz Meher K Prakash Alain M Schoepfer Bettina M Prinz Vavricka Beat Müllhaupt Michael Fried Kuno Lehmann Rudolf W Ammann Stephan R Vavricka | 2014 | World Journal of Gastroenterology2014，20，19： | 5 |
| 3 | Physiology of gastric enterochromaffin-like cells显示文摘 | PRINZ C ZANNER R GRATZL M | 2003 | Ann Rev Physiol2003，65，： | 1 |
| 4 | School bonding in children and adolescents : Conceptualization, assessment, and associat- ed variables 显示文摘 | Maddox S J Prinz R J | 2003 | Clinical Child and Family Psychology Review2003，6，1： | 1 |
| 5 | Measurement of Temperature and Reaction Species in the Cathode Diffusion Layer of a Free- Convection Fuel Cell 显示文摘 | Fabian T O' Hayre R Prinz F B | 2007 | Journal of The Electrochemical Society2007，154，9： | 1 |
| 6 | Genetic analysis of three US population groups using an X-chromosomal STR decaplex显示文摘 | Gomes I Prinz M Pereira R | 2007 | Int J Legal Med2007，121，3： | 1 |
| 7 | Potent family-18 chitinase inhibitors X-ray structures, affinities, and binding mechanisms显示文摘 | PANTOOM S VETTER I R PRINZ H | 2011 | Journal of Biological Chemistry2011，286，24： | 1 |
| 8 | The CR (Renazzo-type) carbonaceous chondrite group and its implications显示文摘 | Weisberg M K Prinz M Clayton R N Mayeda T K | 1993 | Geochim Cosmochim Acta1993，57，7： | 1 |
| 9 | Difficult problems in thyroid surgery显示文摘 | PRINZ R A ROSSI H L KIM A W | 2002 | Curr Probl Surg2002，39，1： | 1 |
| 10 | Synergistic effect of Helicobacter pylori virulence factors and interleukin-1 polymorphisms for the development of severe histological changes in the gastric mucosa显示文摘 | Rad R Prinz C Neu B | 2003 | J Infect Dis2003，188，2： | 1 |
| 11 | Synergistic effect of Helicobaeter pylori virulence factors and interleukin-I polymorphisms for the development of severe histological changes in the gastric mueosa 显示文摘 | Bad R Prinz C Neu B | 2003 | J Infect Dis2003，188，2： | 1 |
| 12 | Analysis of large versus small pheochromocytomas: operative approaches and patient outcomes显示文摘 | Wilhelm S M Prinz R A Barbu A M | 2006 | Surgery2006，140，4： | 1 |
| 13 | Synergistic effect of Helieobacter pylori virulence factors and interleukin-1 polymorphisms for the development of severe histological changes in the gastricmucosa 显示文摘 | Prinz C Neu B | 2003 | J Infect Dis2003，188，2： | 1 |
| 14 | Development of the Meso-and Macroporous Structure of Coals with Rank as Analysed with Small Angle Neutron Scattering and Adsorption Experiments 显示文摘 | Prinz D Pyckhout-Hintzen W Littke R | 2004 | Fuel2004，83，： | 1 |
| 15 | Evaluation of surfactants for use in the spray treatment of iron chlorosis in citrus trees显示文摘 | Neumann P M Prinz R | 1974 | J SciFood Agr1974，25，： | 1 |
| 16 | Left ventricular dyssyn- ehrony predicts clinical response to CRT--a long-term follow-up sin- gle-center prospective observational cohort study 显示文摘 | Prinz C Lehmann R Schwarz M | 2013 | Eehoeardio- graphy2013，30，8： | 1 |
| 17 | Genetic analysis of three US population groups using an X-chromosomal STR decaplex显示文摘 | Gomes I Prinz M Pereira R | 2007 | Int J Legal Med2007，121，3： | 1 |
| 18 | Development of the meso-and macro-porous structure of coals with rank as analyzed with small angle neutron scattering and adsorption experiments显示文摘 | PRINZ D PYCKHOUT-HINTZEN W LITTKE R | 2004 | Fuel2004，83，45： | 1 |
| 19 | Smnatostatin analog treatment of a cervical thoracic duct fistula显示文摘 | Valentine C N Barresi R Prinz R A | 2002 | Head Neck2002，24，： | 1 |
| 20 | Why the Brazil nuts are on top:size segregation of particulate matter by shaking显示文摘 | Rosato A D Strandburg K J Prinz F Swendsen R H | 1987 | Physical Review Letters1987，58，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员