|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Bacterial biota in reflux esophagitis and Barrett's esophagus显示文摘AIM: To identify the bacterial flora in conditions such as Barrett's esophagus and reflux esophagitis to determine if they are similar to normal esophageal flora.METHODS: Using broad-range 16S rDNA PCR,esophageal biopsies were examined from 24 patients [9with normal esophageal mucosa, 12 with gastroesophageal reflux disease (GERD), and 3 with Barrett's esophagus].Two separate broad-range PCR reactions were performed for each patient, and the resulting products were cloned.In one patient with Barrett's esophagus, g9 PCR clones were analyzed.RESULTS: Two separate clones were recovered from each patient (total = 48), representing 24 different species, with 14 species homologous to known bacteria,5 homologous to unidentified bacteria, and 5 were not homologous (<97% identity) to any known bacterial 16S rDNA sequences. Seventeen species were found in the reflux esophagitis patients, 5 in the Barrett's esophagus patients, and 10 in normal esophagus patients.Further analysis concentrating on a single biopsy from an individual with Barrett's esophagus revealed the presence of 21. distinct bacterial species. Members of four phyla were represented, including Bacteroidetes,Firmicutes, Proteobacteria, and Actinobacteria.Microscopic examination of each biopsy demonstrated bacteria in intimate association with the distal esophageal epithelium, suggesting that the presence of these bacteria is not transitory.CONCLUSION: These findings provide evidence for a complex, residential bacterial population in esophageal reflux-related disorders. While much of this biota is present in the normal esophagus, more detailed comparisons may help identify potential disease associations. | Zhiheng Pei Liying Yang Richard M Peek Jr Steven M Levine David T Pride Martin J Blaser | 2005 | World Journal of Gastroenterology2005，11，46： | 11 |
| 2 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 3 | Critical role for Gab2 in transformation by BCR/ABL显示文摘 | Sattler M Mohi M G Pride Y B | | 0，，05： | 1 |
| 4 | The Impact of Channel Leadership Behavior on Intrachannel Conflict 显示文摘 | Patrick L Schul William M Pride and Taylor L Little | 1983 | Journal of Marketing1983，47，3： | 1 |
| 5 | Electrophysiological mechanisms in a canine model of erythromycin-associated long QT syndrome 显示文摘 | Rubart M Pressler ML Pride HP | 1993 | Circulation1993，88，4： | 1 |
| 6 | Tumour necrosis factor- c gene promoter polymorphism in chronic obstructive pulmonary disease 显示文摘 | Higham M A Pride N B Alikhan A | 2000 | Eur Respir J2000，15，2： | 1 |
| 7 | Interleukin-12 redirects murine immune responses to soluble or aluminum phosphate adsorbed HSV-2 glycoprotein D towards Thl and CD4 + CTL responses 显示文摘 | Cooper D Pride M W Guo M | 2004 | Vaccine2004，23，2： | 1 |
| 8 | A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase显示文摘 | Sattler M Pride YB Ma P | 2003 | Cancer Res2003，63，17： | 1 |
| 9 | Electroseismic waves from point sourcesi n layered media显示文摘 | Haartsen M W and Pride S R | 1997 | J Geophys Res1997，102，24： | 1 |
| 10 | Seismic attenuation due to wave-induced flow显示文摘 | PRIDE S R BERRYMAN J G HARRIS J M | 2004 | Journal of Geophysical Re- search2004，109，01： | 1 |
| 11 | Strategic adaptability and firm performance: A market-contingent perspective 显示文摘 | McKee D O Varadarajan P R Pride W M | 1989 | Journal of Marketing1989，53，： | 1 |
| 12 | Seismic attenuation due to wave-induced flow显示文摘 | Pride S R Berryman J G Harris J M | | 0，，： | 1 |
| 13 | Management of a renal artery aneurysm with coil embolization显示文摘 | Pride Y B Nguyen M C Garcia L A | 2008 | J Invasive Cardiol2008，20，： | 1 |
| 14 | A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPRMET tyrosine kinase显示文摘 | Attler M Pride YB | 2003 | Cancer Res2003，63，17： | 1 |
| 15 | Progress in the active immunotherapeutic approach to Alzheimer's disease: clinical investigations into AN1792-associated meningoencephalitis显示文摘 | Pride M Seubert P Grundman M | 2008 | Neurodegener Dis2008，5，34： | 1 |
| 16 | Interleukin-12 redirects murine immune responses to soluble or aluminum phosphate adsorbed HSV-2 glycoprotein D towards Thl and CD4 +CTL responses 显示文摘 | Cooper D Pride MW Guo M et ol | 2004 | Vaccine2004，23，2： | 1 |
| 17 | SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL 显示文摘 | Sattler M Verma S Pride YB Salgia R Rohrschneider LR Griffin JD | 2001 | J Biol Chem2001，276，： | 1 |
| 18 | Electrophysiological mechanisms in a canine model of erythromycin-associated long QT syndrome显示文摘 | Pressler ML Pride HP | 1993 | Circulation1993，88，： | 1 |
| 19 | A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase显示文摘 | Sattler M Pride YB Ma P | 2003 | Cancer Res2003，63，17： | 1 |
| 20 | Seismic attenuation due towave-induced flow显示文摘 | Pride S R Berryman J G Harris J M | 2004 | Journal of Geophysical Research2004，109，01： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员