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| 1 | 狂犬病预防控制技术指南(2016版)显示文摘狂犬病是由狂犬病病毒感染引起的一种动物源性传染病,临床大多表现为特异性恐风、恐水、咽肌痉挛、进行性瘫痪等。近年来,狂犬病报告死亡数一直位居我国法定报告传染病前列,给人民群众生命健康带来严重威胁。为指导基层疾控机构做好狂犬病的预防控制工作,尤其是暴露后的预防处置,降低狂犬病所致死亡,中国疾病预防控制中心组织专家,参考世界卫生组织和美国疾控中心的技术指南,以及国内外最新研究进展,制定了《狂犬病预防控制技术指南(2016版)》。本指南系统回顾了狂犬病的病原学、临床学、实验室诊断、流行病学、疫苗和被动免疫制剂的种类、机制、效果、安全性和不良反应监测与处置,以及暴露预防处置方法等内容的科学证据,在此基础上对狂犬病暴露前和暴露后预防处置的伤口处置、疫苗接种和被动免疫制剂使用等技术给出了推荐建议。本指南适用于从事狂犬病防控工作的各级各类疾病预防控制机构、狂犬病暴露预防处置门诊、医疗机构感染科和急诊科等专业人员。根据狂犬病的国内外研究进展,本指南今后将不断更新、完善。 | Chinese Center for Disease Control and Prevention | 2016 | 中国病毒病杂志2016，6，3： | 84 |
| 2 | 全国艾滋病检测技术规范(2015年修订版)显示文摘前言艾滋病在我国的流行已数十年,随着感染者和临床病人的不断增加、感染人群的变化,艾滋病检测工作量逐渐加大,对监测和检测的需求也不断增加,承担艾滋病检测的实验室已遍及全国各级医疗、疾病预防控制、采供血、妇幼保健机构,出入境检验检疫、军队等各个系统。 | Chinese Center for Disease Control and Prevention | 2016 | 中国病毒病杂志2016，6，6： | 164 |
| 3 | Morphological and functional changes of mitochondria in apoptotic esophageal carcinoma cells induced by arsenic trioxide显示文摘AIM:To demonstrate that mitochondrial morphological andfunctional changes are an important intermediate link in thecourse of apoptosis in esophageal carcinoma calls inducedby As_2O_3.METHODS:The esophageal carcinoma call line SHEEC1,established in our laboratory,was cultured in 199 growthmedium,supplemented with 100mL·L^(-1)calf serum and3 mol·L^(-1)As_2O_3(the same below).After 2,4,6,12,24 hof drug adding,the SHEECl calls were collected for light-and electron-microscopic examination.The mitochondriawere labeled by Rhodamine fluorescence probe and thefluorescence intensity of the mitochondria was measured byflow cytorneter and cytofluorimetric analysis.Further,themitochondrial transmembrane potential(MTP,ΔΨm)change was also calculated.RESULTS:The mitochondrial morphological change afteradding As_2O_3 could be divided into three stages.In theearly-stage(2-6h)after adding As203,an adaptiveproliferation of mitochondria appeared;in the mid-stage(6-12 h)a degenerative change was observed;and in the late-stage(12-24 h)the mitochondria swelled with outermembrane broken down and then calls death with apoptoticchanges of nucleus.The functional change of themitochondria indicated by fluorescent intensity,whichreflected the MTP status of mitochondria,was in accordancewith morphological change of the mitochondria.Thefluorescent intensity increased at early-stage,decUned inmid-stage and decreased to the lowest in the late-stage.24h after As_2O_3 adding,the cell nucleus showed typicalapoptotic changes.CONCLUSION:Under the inducement of As_2O_3,the earlyapoptotic changes of SHEEC1 cells ware the apparentmorphological and functional changes of mitochondria,afterwards the nucleus changes followed.It is consideredthat changes of mitochondria are an important intermediatelink in the course of apoptosis of esophageal carcinoma cells induced by As_2O_3. | Zhong-Ying Shen Jian Shen Qiao-Shan Li Department of Pathology,Medical College of Shantou University,Shantou 515031,Guandong Province,China Cai-Yun Chen Central Lab.Medical College of Shantou University Jiong-Yu Chen Central Lab.of Tumor Hospital,Medical College of Shantou University Yi Zeng Institute of Virology,Chinese Academy of Preventive Medicine,Beijing 100052,China | 2002 | World Journal of Gastroenterology2002，8，1： | 35 |
| 4 | Stability of SARS Coronavirus in Human Specimens and Environment and Its Sensitivity to Heating and UV Irradiation显示文摘The causal agent for SARS is considered as a novel coronavirus that has never been described both in human and animals previously. The stability of SARS coronavirus in human specimens and in environments was studied. Methods Using a SARS coronavirus strain CoV-P9,which was isolated from pharyngeal swab of a probable SARS case in Beijing, its stability in mimic human specimens and in mimic environment including surfaces of commonly used materials or in household conditions, as well as its resistances to temperature and UV irradiation were analyzed. A total of 106 TCID50 viruses were placed in each tested condition, and changes of the viral infectivity in samples after treatments were measured by evaluating cytopathic effect (CPE) in cell line Vero-E6 at 48 h after infectionn. Results The results showed that SARS coronavirus in the testing condition could survive in serum, 1:20 diluted sputum and feces for at least 96 h, whereas it could remain alive in urine for at least 72 h with a low level of infectivity. The survival abilities on the surfaces of eight different materials and in water were quite comparable, revealing reduction of infectivity after 72 to 96 h exposure. Viruses stayed stable at 4℃, at room temperature (20℃) and at 37℃ for at least 2 h without remarkable change in the infectious ability in cells, but were convened to be non-infectious after 90-, 60- and 30-min exposure at 56℃, at 67℃ and at 75℃, respectively. Irradiation of UV for 60 min on the virus in culture medium resulted in the destruction of viral infectivity at an undetectable level. Conclusion The survival ability of SARS coronavirus in human specimens and in environments seems to be relatively strong. Heating and UV irradiation can efficiently eliminate the viral infectivity. | SHU-MING DUAN, XIN-SHENG ZHAO, RUI-FU WEN, JING-JING HUANG, GUO-HUA PI, SU-XIANG ZHANG, JUN HAN, SHENG-LI BI, LI RUAN, XIAO-PING DONGAND SARS RESEARCH TEAMInstitute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention,Ying-Xin Rd. 100, Beijing 100052, China | 2003 | Biomedical and Environmental Sciences2003，16，3： | 29 |
| 5 | 中国丙型病毒性肝炎医院感染防控指南显示文摘丙型病毒性肝炎是一种主要经血液传播的疾病,丙型病毒性肝炎病毒(HCV)慢性感染可导致肝脏慢性炎症坏死及纤维化,部分患者可发展为肝硬化甚至肝细胞癌(HCC),对患者的健康和生命危害极大,已成为严重的社会和公共卫生问题。由于丙型病毒性肝炎患者症状隐匿, | Nosocomial Infection Control Branch of Chinese Preventive Medicine Association | 2013 | 传染病信息2013，26，2： | 28 |
| 6 | Guidelines for diagnosis and treatment of HIV/AIDS in China (2005)显示文摘 | Chinese Medical Association and Chinese Center for Disease Control and Prevention | 2006 | Chinese Medical Journal2006，，19： | 23 |
| 7 | 扩散法被动式个体采样器的设计原理、试验装置和性能评价方法显示文摘介绍了被动式个体采样器的设计原理实验装置和性能评价方法。分别测定了对10种主要室内气体污染物[SO2、NO2、CO2、NH3、HCHO、HF、C6H6、C6H5·CH3、C6H4·(CH3)2、CHCl3]的采样速率(单面采样50~140ml/min,双面增加一倍),相对标准差<10%,与有动力的标准方法相比较,总不确定度<±25%。这种采样器体积小似一枚徽章,重量轻仅10g,使用方便。现场验证和使用表明,可适用于室内空气污染和个体接触量的监测。 | Cui Jiusi(Institute of Environmental Health Monitoring, Chinese Academy of Preventive Medicine, Beijing 100021, China) | 1994 | 卫生研究1994，23，S1： | 23 |
| 8 | 中国成人乙型肝炎免疫预防技术指南显示文摘一、引言
乙型肝炎(乙肝)是由乙肝病毒(HBV)引起的以肝脏损坏为主要病变的传染病,全球均有分布,但我国是HBV感染率较高的国家。我国自1992年起在全国实施新生儿接种乙肝疫苗工作,并将乙肝疫苗纳入儿童计划免疫管理。1992和2006年我国开展了两次乙肝血清流行病学调查, | Chinese Prevention Medicine Association,National Immunization Program,Chinese Center for Disease Control and Prevention | 2012 | 中国病毒病杂志2012，2，1： | 22 |
| 9 | 钢筋混凝土框架结构拟静力倒塌试验研究及数值模拟竞赛Ⅲ:模拟结果分析显示文摘为研究汶川地震中钢筋混凝土框架结构震害机理,清华大学开展了钢筋混凝土框架结构拟静力倒塌的系列试验研究,包括1个3层4跨RC框架、2个关键梁柱节点和4个关键框架柱。结合试验举行了相应的数值模拟分析竞赛,并将试验和数值模拟结果全部在互联网上公布,供有关科研和工程人员参考。本文介绍了钢筋混凝土框架柱、节点和整体框架的数值模拟竞赛结果,以及相应的结论和建议。 | Collapse Prevention Committee of Architectural Society of China | 2012 | 建筑结构2012，42，11： | 23 |
| 10 | Telomere and telomerase in the initial stage of immortalization of esophageal epithelial cell显示文摘AIM: To search for the biomarker of cellular immortalization,the telomere length, telomerase activity and its subunits incultured epithelial cells of human fetal esophagus in theprocess of immortalization.METHODS: The transgenic cell line of human fetalesophageal epithelium (SHEE) was established with E6 E7genes of bt man papillomavirus (HPV) type 18 in ourlaboratory. Morphological phenotype of cultured SHEE cellsfrom the 6th to 30th passages, was examined by phasecontrast microscopy, the telomere length was assayed bySouthern blot method, and the activity of telomerase wasanalyzed by telomeric repeat amplification protocol (TRAP).Expressions of subunits of telomerase, hTR and hTERT,were assessed by RT-PCR. DNA content in cell cycle wasdetected by flow cytometry. The cell apoptosis wasexamined by electron microscopy (EM) and TUNEL label.RESULTS: SHEE cells from the 6 th to 10 th passagesshowed cellular proliferation with a good differentiation.From the 12 th to the 16 th passages, many senescent andapoptotic cells appeared, and the telomere length sharplyshortened from 23 kb to 17 kb without expression of hTERTand telornerase activity. At the 20 th passage, SHEE cellsovercame the senescence and apoptosis and restored theirproliferative activity with expression of telomerase andhTERT at low levels, but the telomere length shortenedcontinuously to the lowest of 3 kb. After the 30 th passagecells proliferation was restored by increment of cells at S andG2M phase in the cell cycle end telomerase activity expressedat high levels and with maintenance of telomere length.CONCLUSION: At the early stage of SHEE cells, telomeresare shortened without expression of telomerase and hTERTcausing cellular senescence and cell death. From the 20 thto the 30 th passages, the activation of telomerase andmaintenance of telomere length show a progressive processfor immortalization of esophageal epithelial cells. Theexpression of telomerase may constitute a biomarker fordetection of immortalization of cells. | Zhong-Ying Shen Li-Yan Xu Wei-Jia Cai Min-Hua Chen Jian Shen,Department of Tumor Pathology,Medical College of Shantou University,Shantou 515031,Guangdong Province,China En-Min Li,Department of Biochemistry and Molecular Biology,Medical College of Shantou University,Shantou 515031,Guangdong Province,China Yi Zeng,Institute of Virology,Chinese Academy of Preventive Medicine,Beijing 100052,China | 2002 | World Journal of Gastroenterology2002，8，2： | 21 |
| 11 | 肠道病毒71型灭活疫苗使用技术指南显示文摘肠道病毒71型(enterovirus type 71,EV71)是人类肠道病毒的一种。EV71感染可引起多种疾病,其中以手足口病(hand,foot and mouth disease,HFMD)最为常见。2007年以来,EV71感染相关HFMD在我国婴幼儿人群中持续流行,发病率高,并导致一定比例的患儿死亡。由于EV71病毒主要通过接触传播,儿童普遍易感且隐性感染比例高,常规卫生学预防措施实施难度大、防控效果差。 | Chinese Center for Disease Control and Prevention | 2016 | 中国病毒病杂志2016，6，4： | 20 |
| 12 | Meta-analysis of the relationship between Epstein-Barr virus infection and clinicopathological features of patients with gastric carcinoma显示文摘Epstein-Barr virus (EBV) infection has been causally associated with occurrence of many malignant neoplasms. EBV-encoded small RNAs (EBERs) have been detected from about 10% of gastric carcinoma tissue cells, suggesting that EBV infection is associated with the development of gastric carcinoma. The present study pooled the data from the papers concerning EBV-related gastric cancers and performed a meta-analysis of 22 research papers. Among these papers, a total of 5475 cases with gastric cancer were enrolled, of whom 411 cases were found EBV-positive, with the EBV-positive rate being 7.5%. Among the EBV-positive gastric cancer cases, the detection rate was 11.1% in males and 3.0% in females. Compared with EBV-negative gastric cancer, EBV-positive gastric cancer had less lymph node metastasis. Based on the histological typing, of the EBV-positive gastric cancers, the diffuse type was 8.1%, and intestinal type was 8.0%. The examined specimen types included stored paraffin blocks and fresh surgically removed specimens, their EBV positive rates were 7.9% and 6.5% respectively. In terms of geographical distribution, the detection rate of EBV-positive gastric cancer was 9.4% in America, 6.1% in Asia and 9.1% in Europe. Meta-analysis showed that EBV infection occurred only in gastric cancer tissue cells and was significantly associated with the patients’ gender, lymph node metastases, and the location where tumor tissue generated and geographical distribution (P<0.05), but was not significantly associated with the patients’ histological types of tumor and the types of specimens (P>0.05). These results suggested that EBV-positive gastric cancer has distinct clinicopathological features. | LI ShuYing1,2, DU HaiJun3, WANG Zhan3, ZHOU Ling3, ZHAO XiaoYu1 & ZENG Yi3 1 College of Life Sciences, Hebei University, Baoding 071002, China 2 Department of Pathogenic Biology, Faculty of Biological Science, North China Coal Medical College, Tangshan 063000, China 3 National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (Chinese CDC), State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Beijing 100052, China | 2010 | Science China(Life Sciences)2010，53，4： | 17 |
| 13 | Emergency assessment of seismic landslide susceptibility: a case study of the 2008 Wenchuan earthquake affected area显示文摘The 8.0 Mw Wenchuan earthquake triggered widespread and large scale landslides in mountainous regions.An approach was used to map and assess landslide susceptibility in a given area.A numerical rating system was applied to fi ve factors that contribute to slope instability.Factors such as lithology,topography,streams and faults have an important influence as event-controlling factors for landslide susceptibility assessment.A f inal map is provided to show areas of low,medium,and high landslide susceptibility.Areas identifi ed as having high landslide susceptibility were located in the central,northeastern,and far south regions of the study area.The assessment results will help decision makers to select safe sites for emergency placement of refuges and plan for future reconstruction.The maps may also be used as a basis for landslide risk management in the study area. | Tang Chuan,Zhu Jing and Liang Jingtao State Key Laboratory of Geo-Hazard Prevention,Chengdu University of Technology,Chengdu 610059,China Professor Associate Professor Graduate Student | 2009 | Earthquake Engineering and Engineering Vibration2009，8，2： | 16 |
| 14 | Generation of a recombinant herpes simplex virus which can provide packaging function for recombinant adeno-associated virus显示文摘The generation of a recombinant HSV (rHSV) that can provide packaging function for rAAV production is described. A set of cosmids including cos48, cos28, cos6, cos14 and cos56, which represents the HSV-1 genome was used for generation of this rHSV. Rep and cap genes of AAV-2 were inserted into Xba Ⅰ site of UL2 gene on cos6, generating cos6-rcΔUL2. After being digested with Pac Ⅰ , cos6-rcΔUL2 and the other 4 cosmids were cotrans-fected into BHK-21 cells. The recombinant virus HSV1-rc/ΔUL2 carrying rep and cap genes was generated due to the homologous recombination of the 5 cosmids. The results showed that the existence of rep and cap genes on this rHSV was stable from passage to passage and the rHSV could support the packaging of rAAV either in cells transiently transfected with AAV vector or in stable cell line harboring AAV vector. Further modification of this rHSV and optimization of conditions involved in rAAV preparation may lead to a large-scale production of rAAV in the near future. | WU Zhijian, WU Xiaobing and HOU YundeState Key Laboratory for Molecular Virology and Genetic Engineering , Institute of Virology , Chinese Academy of Preventive Medicine , Beijing 100052, China Corresponding author | 1999 | Chinese Science Bulletin1999，44，8： | 15 |
| 15 | 1997年全国艾滋病哨点监测报告显示文摘1997年,全国HIV监测哨点共调整为60个,分布在27个省(自治区、直辖市)。性病门诊哨点和长卡哨点中只检出极少数HIV感染者。1997年,在3个暗娼哨点中的检出率约为1%~2%,而1996年同期仅为不到0.5%;在12个吸毒哨点中有7个哨点(包括2个新增哨点)报告了HIV感染者,而在1996年同期8个哨点中有3个哨点报告了感染者。新疆自治区报告了83例(20.8%)感染者,而在前几年同期同一哨点只有32例(8.0%)。在大部分吸毒监测哨点中的静注比例正不断增加或保持一个较高水平。暗娼人群中有60%从不使用避孕套。该监测结果表明,局部地区吸毒者中HIV感染率在不断上升,HIV波及的地区在不断地增多,HIV感染已开始向性乱人群扩散;可引起HIV流行的危险因素在不断增加。 | Department of Disease Control,Ministry of Health,People′s Republic of China 1 Center for AIDS Surveillance,Chinese Academy of Preventive Medicine 2 Group of National HIV Sentinel Surveillance Program (Written by Qu Shuquan 2,Sun Xinhua 1,Zheng X | 1998 | 中国性病艾滋病防治1998，4，4： | 15 |
| 16 | Application of cusp catastrophe theory to reliability analysis of slopes in open-pit mines显示文摘A method of slope reliability analysis was developed by imposing a state equation on the limit equilibrium theory, given the basis of a fixed safety factor technique. Among the many problems of reliability analysis, the most important problem is to find a performance function. We have created a new method of building a limit state equation for planar slip surfaces by applying the mathematical cusp catastrophe theory. This new technique overcomes the defects in the traditional rigid limit equilibrium theory and offers a new way for studying the reliability problem of planar slip surfaces. Consequently, we applied the technique to a case of an open-pit mine and compared our results with that of the traditional approach. From the results we conclude that both methods are essentially consistent, but the reliability index calculated by the traditional model is lower than that from the catastrophic model. The catastrophe model takes into consideration two possible situations of a slope being in the limit equilibrium condition, i.e., it may or may not slip. In the traditional method, however, a slope is definitely considered as slipping when it meets the condition of a limit equilibrium. We conclude that the catastrophe model has more actual and instructive importance compared to the traditional model. | YANG Kun, WANG Tongxu, MA Zhitao Key Laboratory of Mine Disaster Prevention and Control, Shandong University of Science and Technology, Qingdao 266510, China | 2010 | Mining Science and Technology2010，20，1： | 15 |
| 17 | Complete nucleotide sequence of a novel porcine circovirus-like agent and its infectivity in vitro显示文摘A novel agent (hence termed as P2) was isolated from pig sera in China, which contained covalently bound circular genomic DNAs of 993 nucleotides. Sequence analyses indicated that the agent was closely related to the porcine circovirus (PCV). The molecular clone of P2 was constructed subsequently and used for the following studies. Intracytoplasmic inclusions and intranuclear inclusions were only found in PK-15 cells transfected with the tandem dimer of P2 molecular DNA clone. Intracytoplasmic inclusions were round or irregular in shape and 0.1-0.4 μm in diameter, and intranuclear inclusions were electronically denser than intracytoplasmic inclusions and had two general shapes: round/small (0.1 μm in diameter) and hexagonal/large (0.5―1.4 μm in diameter). The inclusions were not membranously bound. The cells transfected with the tandem dimer of P2 molecular DNA clone were tested positive for P2 DNA at passages 5. The P2 antigen could be detected in both transfected and passaged PK-15 cells. This is the first report regarding the complete nucleotide sequence of a small DNA genome in a circovirus-like infectious agent in vitro. | WEN LiBin1, HE KongWang1, YANG HanChun2, NI YanXiu1, ZHANG XueHan1, GUO RongLi1 & PAN QunXin1 1 Key Laboratory of Animal and Poultry Diseases Diagnostic of the Ministry of Agriculture, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China 2 Key Laboratory of Preventive Veterinary Medicine of Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China | 2008 | Science China(Life Sciences)2008，51，5： | 14 |
| 18 | Human avian influenza A (H5N1) virus infection in China显示文摘Highly pathogenic influenza A (H5N1) virus causes a widespread poultry deaths worldwide. The first human H5N1 infected case was reported in Hong Kong Special Administrative Region of China in 1997. Since then, the virus re-emerged in 2003 and continues to infect people worldwide. Currently, over 400 human infections have been reported in more than 15 countries and mortality rate is greater than 60%. H5N1 viruses still pose a potential pandemic threat in the future because of the continuing global spread and evolution. Here, we summarize the epidemiological, clinical and virological characteristics of human H5N1 infection in China monitored and identified by our national surveillance systems. | XU CuiLin, DONG LiBo, XIN Li, LAN Yu, CHEN YongKun, YANG LiMei & SHU YueLong State Key Laboratory for Viral Genetic and Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), Beijing 100052, China | 2009 | Science China(Life Sciences)2009，52，5： | 14 |
| 19 | Studies on Human Dietary Requirements and Safe Range of Dietary Intakes of Selenium in China and Their Application in the Prevention of Related Endemic Diseases显示文摘The human dietary selenium requirement in China has been estimated by various methods. The minimum dietary selenium requircment for the prevention of Keshan disease (KD) was found to be around 17 μg/d. On the other hand, an intake of 40 μg/d is required to maintain the plasma glutathione peroxidase (GPx) activity at plateau. Hence 40 μg/d is considered as the adequate dietary selenium requirement. Studies conducted in a chronic selenosis area indicate thai the toxic dietary selenlum inlake (adverse effect level), which would maintain the characteristic fingernail changes, was approximately 1600 μg/d. The mean value of dietary selenium intakes, which enabled the five patients to recover from fingernail lesions, was found to be 819 ±126μg/d. At a 95% confidence limit, the lower limit is around 600μg/d. Therefore, 600 and 400μg/d were suggested as the individual daily maximum safe selenium intake and the safe dietary selenium intake, respectively,The results were used in the prevention of Se-related endemic KD and Kashin-Beck disease (KBD) | YANG GUANG-QI AND XIA YI-MING (Department of Trace Element Nutrition, Institute of Nutrition and Food Hygiene, Chinese Academy of Preventive Medicine, Beijing 100050, China) | 1995 | Biomedical and Environmental Sciences1995，8，3： | 14 |
| 20 | Risk Factors for Lung Cancer in Non-smokers in Xuanwei County of China显示文摘Tobacco smoking and some types of occupational exposures have consistently been considered as important etiologic factors of lung cancer in industrial countrie.At the First World Conference of Lung Cancer(Wyndwer,1983),it was stressed that more attention should be paid to finding out the causes of lung cancer in non-smokers. In Xuanwei County,Yunnan Province,annual lung cancer death rate was 27.7per 100,000 in males,among China's highest,and 25.3per 100,000 in females,the China's highest.The remale's lung cancer death rate in Xuanwei County was even much higher than that of the same period in USA white women(ECACM,1979;Mulvihill,1976),Marked district variation in cancer mortality exists within xuanwei County.The county can be ivided into high-,medium-and low-mortality areas.Over90% of the population are farmers.The local residents traditionally burned three major kinds of fuels:“smoky” coal,“smokeless”coal and “wood”,for heating and cooking.The three lung cancer high mortality areas,including “Chengguan”,“Rongcheng”and “Laibin”communes,mainly burned the “smoky”!coal from Laibin smoky-coal mine.The fuel was burned in a shallow,unventiated fire pit in the floor of the dwelling.Fuel burning in shallow unventialated pits has resulted in high indoor air pollution levels.The concentrations of airborne particles(pm10) inside houses during smoky coal and wood combustion were very high.Indoor concentration of suspended particulates and dichloromethane extractable organics were 244.4mg/m^3 and 17.6mg/m^3 in burning of “smoky”coal;22.2mg/m^3,12.3mg/m^3 for burning wood;and 1.8mg/m^3,0.5mg/m^3 for burning of smokeless coals.Levels of individual polycyclic aromatic hydrocarbons.including benzo(a)pyrene,were generally highest during burning of smoky coal,intermediate in burning wood,and least in smokeless coal.Women did most household chores.which include starting fire and cooking.Less than 0.2% of females smoked tobacco.The population-based casecontrol study presented here is to evaluate the influence of factors on the occurrence of lung cancer in non-smoking women in Xuanwei County and to supplement the etiologic factors of lung cancer in Xuanwei County. | LAN QING, CHEN WEI, CHEN HONG, AND HE XING-ZHOUInstitute of Environmental Health and Engineering, Chinese Academy of Preventive Medicine 29 Nan Wei Road, Beijing 100050, China | 1993 | Biomedical and Environmental Sciences1993，6，2： | 13 |
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