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| 1 | Opisthorchis viverrini:The carcinogenic human liver fluke显示文摘Opisthorchiasis caused by Opisthorchis viverrini remains a major public health problem in many parts of Southeast Asia, including Thailand, Lao PDR, Vietnam and Cambodia. The infection is associated with a number of hepatobiliary diseases, including cholangitis, obstructive jaundice, hepatomegaly, cholecystitis and cholelithiasis. Multi-factorial etiology of cholangiocarcinoma, mechanical damage, parasite secretions, and immunopathology may enhance cholangiocarcinogenesis. Moreover, both experimental and epidemiological evidences strongly implicate liver fluke infection as the major risk factor in cholangiocarcinoma, cancer of the bile ducts. The liver fluke infection is induced by eating raw or uncooked fish products that is the tradition and popular in the northeastern and northern region, particularly in rural areas, of Thailand. The health education programs to prevent and control opisthorchiasis are still required in the high-risk areas. | Natthawut Kaewpitoon Soraya J Kaewpitoon Prasit Pengsaa Banchob Sripa | 2008 | World Journal of Gastroenterology2008，14，5： | 6 |
| 2 | Food-borne parasitic zoonosis: Distribution of trichinosis in Thailand显示文摘Trichinosis is among the most common food-borne parasitic zoonoses in Thailand and many outbreaks are reported each year. This paper investigates the distribution of the disease in regions of north, north-east, central and south Thailand. Between the earliest recorded of outbreak of trichinosis in Mae Hong Son Province in 1962 and 2006, there have been 135 outbreaks involving 7340 patients and 97 deaths in Thailand. The highest number of cases, 557, was recorded in 1983. Most infected patients were in the 35-44 year age group, and the disease occurred more frequently in men than women during 1962-2003, with no significant sex difference during 2004-2006. Outbreaks were most common in the northern areas, especially in rural areas where raw and under-cooked pork and/or wild animals are eaten. Human infections occur annually in northern Thailand during communal feasts celebrating the Thai New Year. Trichinosis causes have been reported every year, supporting the need for planning education programs. | Natthawut Kaewpitoon Soraya Jatesadapattaya Kaewpitoon Prasit Pengsaa | 2008 | World Journal of Gastroenterology2008，14，22： | 6 |
| 3 | Interleukin-1βinduces human cementoblasts to support osteoclastogenesis显示文摘Injury of the periodontium followed by inflammatory response often leads to root resorption. Resorption is accomplished by osteoclasts and their generation may depend on an interaction with the cells in direct contact with the root, the cementoblasts.Our study aimed to investigate the role of human cementoblasts in the formation of osteoclasts and the effect of interleukin(IL)-1β hereupon. Extracted teeth from healthy volunteers were subjected to sequential digestion by type I collagenase and trypsin.The effect of enzymatic digestion on the presence of cells on the root surface was analyzed by histology. Gene expression of primary human cementoblasts(p HCB) was compared with a human cementoblast cell line(HCEM). The p HCBs were analyzed for their expression of IL-1 receptors as well as of receptor activator of nuclear factor kappa-B ligand(RANKL) and osteoprotegerin(OPG). In a co-culture system consisting of osteoclast precursors(blood monocytes) and p HCBs, the formation of osteoclasts and their resorptive activity was assessed by osteo-assay and ivory slices. The cells obtained after a 120 min enzyme digestion expressed the highest level of bone sialoprotein, similar to that of HCEM. This fraction of isolated cells also shared a similar expression pattern of IL-1 receptors(IL1-R1 and IL1-R2). Treatment with IL-1β potently upregulated RANKL expression but not of OPG. p HCBs were shown to induce the formation of functional osteoclasts. This capacity was significantly stimulated by pretreating the p HCBs with IL-1β prior to their co-culture with human blood monocytes. Our study demonstrated that cementoblasts have the capacity to induce osteoclastogenesis, a capacity strongly promoted by IL-1β. These results may explain why osteoclasts can be formed next to the root of teeth. | nam c-n huynh vincent everts prasit pavasant ruchanee s ampornaramveth | 2017 | International Journal of Oral Science2017，9，4： | 5 |
| 4 | Curcumin inhibits WT1 gene expression in human leukemic K562 cells显示文摘瞄准:Wilm 的 tumor1 (WT1 ) 基因高度在骨髓的和淋巴的起源的白血病的胚细胞被表示。因此, WT1 mRNA 和蛋白质用作为白血病的察觉答应肿瘤标记并且疾病前进监视。这研究的目的是在人的白血病的房间线 K562 在 WT1 基因表示上调查杂种狗枯茗的 modulating 效果。方法:K562 房间线上的杂种狗枯茗的细胞毒性被使用 3-(4,5-dimethyl-2 thiazoyl ) 评估 -2,5-diphenyl-tetrazolium 溴化物(MTT ) 试金。K562 房间线为 13 d 与杂种狗枯茗(5, 10,或 15 micromol/L ) 的非细胞毒素的剂量被对待。WT1 蛋白质和 WT1 mRNA 的表示层次被西方的污点分析和反向的抄写聚合酶链反应(RT-PCR ) 分别地估计。结果:姜黄色素在 50% 点与禁止的集中在 K562 白血病的房间上有细胞毒素的效果(IC50 ) 约 20 microg/mL (54.3 micromol/L ) 。在为 2 d 的 5, 10,和 15 micromol/L 的集中,杂种狗枯茗的非细胞毒素的剂量减少了在 K562 房间的 WT1 蛋白质和 WT1 mRNA 的水平以一种剂量依赖者方式排队。同样,在 10 micromol/L 的集中的杂种狗枯茗显著地减少了以一种时间依赖者方式的 WT1 蛋白质和 mRNA 的水平。结论:杂种狗枯茗的禁止的效果在 WT1 蛋白质和 WT1 mRNA 的层次与减少被联系。当前的学习为未来提供一个分子的基础在白血病的病人的临床的试用。因此,杂种狗枯茗能是为人的白血病的一个有希望的化学疗法的代理人。 | Songyot ANUCHAPREEDA PattraTHANARATTANAKORN SomjaiSITTIPREECHACHARN Prasit CHANARAT Pornngarm LIMTRAKUL | 2006 | Acta Pharmacologica Sinica2006，27，3： | 3 |
| 5 | Knowledge, attitude and practice related to liver fluke infection in northeast Thailand显示文摘AIM: To investigate the knowledge, attitude and practice (KAP) in prevention and control of liver fluke infection in northeast Thailand. METHODS: A descriptive KAP survey pertaining to liver fluke infection was carried out in June 2005 to October 2006 using structured questionnaires. Data were collected by questionnaires consisting of general parameters, knowledge, attitude, practice, and a history of participation in the prevention and control of liver fluke infection.RESULTS: A total of 1077 persons who were inter-viewed and completed the questionnaires were enrolled in the study. The majority were females (69.5%) and many of them were 15-20 years of age (37.26%). The questionnaires revealed that information resources on liver fluke infection included local public health volunteers (31.37%), public health officers (18.72%), televisions (14.38%), local heads of sub-districts (12.31%), doctors and nurses (9.18%), newspaper (5.72), internets (5.37%), and others (12.95%). Fifty-five point eleven percent of the population had a good level of liver fluke knowledge concerning the mode of disease transmission and 79.72% of the population had a good level of prevention and control knowledge with regards to defecation and consumption. The attitude and practice in liver fluke prevention and control were also at a good level with a positive awareness, participation, and satisfaction of 72.1% and 60.83% of the persons studied. However, good health behavior was found in 39.26% and 41.42% of the persons studied who had unhygienic defecation and ate raw cyprinoid's fish. The result also showed that 41.25% of the persons studied previously joined prevention and control campaigns. CONCLUSION: The persons studied have a high level of liver fluke knowledge and positive attitude. However, improvement is required regarding personal hygiene specifically with hygienic defecation and consumption of undercooked fish. | Natthawut Kaewpitoon Soraya J Kaewpitoon Prasit Pengsaa Chutigan Pilasri | 2007 | World Journal of Gastroenterology2007，13，12： | 3 |
| 6 | Opisthorchiasis in Thailand: Review and current status显示文摘Opisthorchiasis caused by Opisthorchis viverrini (O. viverrini) remains a major public health problem in many parts of Southeast Asia including Thailand, Lao PDR, Vietnam and Cambodia. The infection is associated with a number of hepatobiliary diseases, including cholangitis, obstructive jaundice, hepatomegaly, cholecystitis, chole- lithiasis and cholangiocarcinoma. The liver fluke infection was induced by eating raw or uncooked fish products that is the tradition and popular in the northeastern and northern region, particularly in rural areas of Thailand. Health education programs to prevent and control opisthorchiasis are still required in high-risk areas. | Natthawut Kaewpitoon Soraya J Kaewpitoon Prasit Pengsaa | 2008 | World Journal of Gastroenterology2008，14，15： | 3 |
| 7 | Prospective study of the prevalence and co-morbidities of obstructive sleep apnea in active-duty army personnel in the three southernmost provinces of Thailand using questionnaire screening显示文摘Background: It is crucial for the army to know the prevalence of obstructive sleep apnea(OSA) syndrome in activeduty army personnel. Little information has been reported on the prevalence of OSA and clinical features in activeduty army personnel. This study was aimed to estimate the prevalence of snoring and risk of developing OSA in activeduty army personnel in Thailand and to identify the co-morbidities of OSA. In total, 1107 participants who were aged20–60 years and were deployed to the three southernmost provinces of Thailand were enrolled. All the participants completed the Phramongkutklao(PMK) Hospital OSA Questionnaire that was modified and validated from the Berlin Questionnaire and underwent physical examination. The participants were 1107 active-duty army personnel in the three southernmost provinces of Thailand, both males and females, aged 20–60 years.Methods: The PMK OSA Questionnaire was used to assess the risk of OSA together with interviewing for snoring,fatigue, falling asleep and day-time sleepiness. Physical examination of the neck, chest and hip circumference,and height was performed. Information concerning physical training, co-morbid diseases, smoking and alcoholic consumption was collected.Results: The prevalence of snoring was 58.5, and 4.8% met the PMK OSA Questionnaire criteria, thus indicating a high risk of OSA. The information obtained indicated that laryngopharyngeal reflux(LPR), current smoking and alcoholic consumption were significantly higher in the high-risk OSA group.Conclusions: Early detection and treatment of OSA in active-duty army personnel are imperative. Physical examination and polysomnography can be used to reveal the high-risk group. High body mess index(BMI), laryngopharyngeal reflux, current smoking and alcoholic consumption are modifiable factors for OSA and are avoidable. A policy to decrease the BMI and risk of LPR, as well as to stop smoking and alcoholic consumption, should be applied. | Anisong Pilakasiri Prasit Mahakit | 2019 | Military Medical Research2019，6，2： | 2 |
| 8 | Enhanced giant dielectric properties and improved nonlinear electrical response in acceptor-donor (Al^(3+), Ta^(5+))-substituted CaCu_(3)Ti_(4)0_(12) ceramics显示文摘The giant dielectric bchavior of CaCu_(3)Ti_(4)0_(12)(CCTO)has been widely investigated owing to its potential applications in electronics;however,the loss tangent(tan8)of this material is too large for many applications.A partial substitution of CCTO ceramics with either Al^(3+) or Ta^(5+)-ions generally results in poorer nonlinear properties and an associated increase in tan8(to~0.29-1.15).However,first-principles calculations showed that self-charge compensation occurs between these two dopant ions when co-doped into Tit sites,which can improve the electrical properties of the grain boundary(GB).Surprisingly,in this study,a greatly enhanced breakdown electric field(~200--6588 V/cm)and nonlinear coefficient(-4.8-15.2)with a significantly reduced tan8(~0.010--0.036)were obtained by simultaneous partial substitution of CCTO with acceptor-donor(Al^(3+),Ta^(5+))dopants to produce(Al^(3+),Ta^(5+))-CCTO ceramics.The reduced tan8 and improved nonlinear properties were attributed to the synergistic effects of the co-dopants in the doped CCTO structure.The signifcant reduction in the mean grain size of the(Al^(3+),Ta^(5+))-CCTO ceramics compared to pure CCTO was mainly because of the Ta^(5+)-ions.Accordingly,the increased GB density due to the reduced grain size and the larger Schottky barrier height(Ф_(b))at the GBs of the co-doped CCTO ceramics were the main reasons for the greatly increased GB resistance,improved nonlinear properties,and reduced tan8 values compared to pure and single-doped CCTO.In addition,high dielectric constant values(ε'≈(0.52-2.7)×10^(4))were obtained.A fine-grained microstructure with highly insulating GBs was obtained by Ta doping,while co-doping with Ta^(5+) and Al^(3+ )resulted in a high Ф_(b).The obtained results are expected to provide useful guidelines for developing new giant dielectric ceramics with excellent dielectric properties. | Jakkree BOONLAKHORN Narong CHANLEK Jedsada MANYAM Pornjuk SREPUSHARAWOOT Sriprajak KRONGSUK Prasit THONGBAI | 2021 | Journal of Advanced Ceramics2021，10，6： | 2 |
| 9 | Liquidity and Capital Structure; The case of Thailand 显示文摘 | Prasit U Seksak J Pornsit J | 2011 | Journal of Multinational Financial Management2011，2，： | 1 |
| 10 | Systematic review of the effect of telmisartan on insulin sensitivity in hypertensive patients with insulin resistance or diabetes显示文摘 | Suksomboon N Poolsup N Prasit T | 2012 | J Clin Pharm Ther2012，37，3： | 1 |
| 11 | Nonlinear Aerostatic Stability Analysis of Suspension Bridges 显示文摘 | BOONYAPINYO V LAUHATANON Y LUKKUNA- PRASIT P | 2006 | Engineering Structures2006，28，5： | 1 |
| 12 | Effect of chlorine on corrosion in drinking water systems显示文摘 | Abigail F Cantor Jae K Park Prasit Vaiyavatjamai | 2003 | American Water Works Association2003，95，5： | 1 |
| 13 | Ethanol production from sweet sorghum juice in batch and fed-batch fermentations by Saccharomyces cerevisiae显示文摘 | Lakkana Laopaiboon Pornthap Thanonkeo Prasit Jaisil Pattana Laopaiboon | 2007 | World Journal of Microbiology and Biotechnology2007，，10： | 1 |
| 14 | Preparation and Characterization of Novei Bone Scaffoids Based on Electrospun Polycaprolactone Fibers Fil ed with Nanoparticles显示文摘 | Patcharaporn W Neeracha S Prasit P | | 0，，01： | 1 |
| 15 | Synthesis and giant dielectric behavior of Cafu3Ti4012 ceramics prepared by polymerized complex method 显示文摘 | CHIVALRAT M PRASIT T SANTI M | 2008 | Materials Chemistry and Physics2008，109，23： | 1 |
| 16 | Elucidating authorship issues as an element of research quality at Thailand’s National Science and Technology Development Agency显示文摘Authorship in a scientific publication is an indicator of significant intellectual contribution in scientific work.Regardless of the discipline,it is important for research-related personnel to receive credit and take responsibility for their publications.There are currently several systems of listing authorship that arise from many factors such as research complexity,pressure to obtain funding,hierarchical structure,and promotion.Some of these may unfortunately lead to authorship abuse.Raising awareness and understanding of authorship guidelines can help prevent abuses and disputes.National Science and Technology Development Agency(NSTDA)is a national research agency of Thailand with about 2000 research staff members.The research emphasis of the agency is mainly technology development for application in broad areas,ranging from engineering to medicine,including forensic science.We conducted a survey to identify the level of awareness of NSTDA research staff and their authorship practices.A questionnaire was designed based on the International Committee of Medical Journal Editors(ICMJE)authorship guidelines and used to survey 15%of randomly selected NSTDA research staff.Nearly 90%of them responded to the interview.Among the respondents,60%were not sure about authorship criteria.When presented with the ICMJE criteria,more than 90%agreed with the criteria except for the third one,approval of the final manuscript before submission,33%of respondents thought that authors are only responsible for their particular contribution.However,nearly 80%agreed that every author is responsible for the integrity of the whole manuscript.These results offered an important foundation for forming a strategy to raise awareness about authorship in NSTDA.Following survey analysis,we organized several seminars and developed learning materials and an authorship guideline to increase the level of awareness of authorship for researchers. | Sudarat Luepongpattana Aviga Soonmongkol Supattra Laorrattanasak Ansucha Prucksunand Prasit Palittapongarnpim | 2021 | Forensic Sciences Research2021，6，3： | 1 |
| 17 | Increasing Incidence of Hip Fracture in Chiang Mai, Thailand显示文摘 | Prasit Wongtriratanachai Sirichai Luevitoonvechkij Thawee Songpatanasilp Siripoj Sribunditkul Taninnit Leerapun Sompant Phadungkiat Sattaya Rojanasthien | 2012 | Journal of Clinical Densitometry2012，，： | 1 |
| 18 | Preparation and characterization of microwave-treated carboxymethyl chitin and carboxymethyl chitosan films for potential use in wound care application显示文摘 | WONGPANIT PANYA SANCHAVANAKIT NEERACHA PAVASANT PRASIT | 2005 | Macromol Biosci2005，5，10： | 1 |
| 19 | Systematic review of the effect of telmisartan on insulin sensitivity in hypertensive patients with insulin resistance or diabetes 显示文摘 | Suksomboon N Poolsup N Prasit T | 2012 | J Clin Pharm Ther2012，37，3： | 1 |
| 20 | Recovery patterns of liver function after complete and partial surgical biliary decompression 显示文摘 | Prasit W | 1996 | Am J Surg1996，171，2： | 1 |
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