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14篇 您的检索式：作者名="Prahalathan"

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		题名	作者	年代	出处	被引量
	1	Effect of morin, a flavonoid against DOCA-salt hypertensive rats:a dose dependent study显示文摘Objective:To determine the protective effect of morin, a flavonoid against deoxycorticosterone acetate(DOCA)-salt induced hypertension in male Wistar rats.Methods:Hypertension was induced in uninephrectomized rats by weekly twice subcutaneous injection of DOCA(25 mg/kg bw) and 1% NaCl in the drinking water for six consecutive weeks. Effect of morin against DOCA-salt induced hypertension was evaluated by measuring blood pressure and performing biochemical estimations and histopathological examination of renal tissues.Results:DOCA-salt hypertensive rats showed considerably increased systolic and diastolic blood pressure,serum hepatic marker enzyme activities such as aspartate aminotransferase(AST), alanine aminotransferase(ALT), alkaline phosphatase(ALP) and gamma-glutamyl transpeptidase(GGT)and renal function markers(urea, uric acid and creatinine) in plasma. Oral administration of morin(25, 50 and 75 mg/kg bw) brought back all the above parameters to near normal level.Histopathology of kidney also confirmed the biochemical findings of this study. The effect at a dose of 50 mg/kg bw of morin was more pronounced than that of the other two doses(25 and 75 mg/kg bw).Conclusions:These findings indicate that morin exhibits strong antihypertensive effect against DOCA-salt induced hypertension.	Prahalathan P Kumar S Raja B	2012	Asian Pacific Journal of Tropical Biomedicine2012，2，6：	2
	2	Reprod lipoic acid ameliorates adriamycin-induced testicular mitochondriopathy显示文摘	Prahalathan C Selvakumar E Varalakshmi P	2005	Toxicol2005，20，1：	1
	3	Vanillic acid prevents the deregulation of lipid metabolism, endothelin 1 and up regulation of endothelial nitric oxide synthase in nitric oxide deficient hypertensive rats显示文摘	Subramanian Kumar Pichavaram Prahalathan Murugesan Saravanakumar Boobalan Raja	2014	European Journal of Pharmacology2014，，：	1
	4	Morin attenuates blood pressure and oxidative stress in deoxycorticosterone acetate-salt hypertensive rats: A biochemical and histopathological evalua- tion显示文摘	Prahalathan P Kumar S RajaB	2013	Metabolism: Clinical and Experimental2013，61，8：	1
	5	Protective effect of DL-alpha-lipoic acid in cyclophospha- mide induced oxidative injury in rat testis显示文摘	Selvakumar E Prahalathan C Mythili Y	2004	Reprod Toxicol2004，19，：	1
	6	Protective effect of lipoic acid on cyclophosphamide-induced testicular toxicity显示文摘	Selvakumar E Prahalathan C Sudharsan PT	2006	Clin Chim Acta2006，367，12：	1
	7	Chemoprotective effect of lipoic acid against cyclophosphamide-induced changes in the rat sperm显示文摘	Selvakumar E Prahalathan C Sudharsan PT	2006	Toxicology2006，217，1：	1
	8	Chemoprotective effect of lipoic acid against cyclophocphamide-induced changes in the rat sperm显示文摘	Prahalathan C Sudharan P T	2006	Toxicology2006，217，7：	1
	9	Lipoic acid ameliorates adriamycin-induced testicular mitochondriopathy显示文摘	Prahalathan C Selvakumar E Varalakshmi P	2005	Reprod Toxicol2005，20，1：	1
	10	Chemoprotective effect of lipoic acid against cyclophosphamide-induced changes in the rat sperm显示文摘	Selvakumar E Prahalathan C Sudharsan P T	2006	Toxicology2006，217，7：	1
	11	Protective effect of dl -α-lipoic acid in cyclophosphamide induced oxidative injury in rat testis显示文摘	Elangovan Selvakumar Chidambaram Prahalathan Yenjerla Mythili Palaninathan Varalakshmi	2004	Reproductive Toxicology2004，，2：	1
	12	Modification ofcyclophosphamide-induced clastogenesis and apoptosis in rats bya-lipoic acid显示文摘	Selvakumar E Prahalathan C Varalakshmi P	2006	Mutat Res2006，606，12：	1
	13	Protective effect of lipoic acid on cyclophosphamide-indueed testieular toxicity显示文摘	SELVAKUMAR E PRAHALATHAN C VARALAKSHMI P	2006	Clin Chim Acta2006，367，12：	1
	14	Modification of cyclophosphamide-induced clastogenesis and apoptosis in rats by alpha-lipoic acid显示文摘	SELVAKUMAR E PRAHALATHAN C VARALAKSHMI P	2006	Mutat Res2006，606，12：	1

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