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| 1 | Neuroendocrine carcinoma of the ampulla of Vater:a clinicopathologic evaluation显示文摘BACKGROUND:Only 105 cases of neuroendocrine tumor(NET)of the ampulla of Vater have been described, mostly as single case reports.The incidence of NET is rising.The changes in incidence may result from changes in detection.This study was to determine the relative incidence and clinicopathological characteristics of high- grade neuroendocrine carcinoma(small cell carcinoma and large cell carcinoma)of the ampulla of Vater at a single institution. METHODS:Sections from paraffin blocks of tumors of the ampulla of Vater taken from 45 patients who underwent Whipple's procedure and 6 patients who underwent palliative bypass between September 2003 and January 2007 were subjected to immunohistochemical analysis.The clinical and pathological data from 5 patients diagnosed with NET of the ampulla of Vater were analyzed. RESULTS:The patients were 3 men and 2 women,ranging in age from 39 to 47 years(mean 44 years).Operative procedures included Whipple's procedure in 4 patients and palliative bypass in 1 patient.Histopathological examination revealed large-cell neuroendocrine carcinoma in 2 patients,small cell carcinoma in 2,and carcinoid in 1.Three patients with high-grade neuroendocrine carcinoma who had undergone Whipple's procedure died at postoperatively 7,11,and 13 months.The patient who had undergone palliative triple bypass died 3 months after surgery.CONCLUSIONS:The relative incidence of high-grade neuroendocrine carcinomas of the ampulla of Vater is higher than that generally expected.The tumors behave aggressively and have a dismal prognosis despite aggressive treatment. | Eswaran Selvakumar Shanmugasundaram Rajendran Tirupporur Govindaswamy Balachandar Devy Gounder Kannan Satyanesan Jeswanth Palaniappan Ravichandran Rajagopal Surendran | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，4： | 7 |
| 2 | Stem cells:An eventual treatment option for heart diseases显示文摘Stem cells are of global excitement for various diseases including heart diseases. It is worth to understand the mechanism or role of stem cells in the treatment of heart failure. Bone marrow derived stem cells are commonly practiced with an aim to improve the function of the heart. The majority of studies have been conducted with acute myocardial infarction and a few has been investigated with the use of stem cells for treating chronic or dilated cardiomyopathy. Heterogeneity in the treated group using stem cells has greatly emerged. Ever increasing demand for any alternative made is of at most priority for cardiomyopathy. Stem cells are of top priority with the current impact that has generated among physicians. However,meticulous selection of proper source is required since redundancy is clearly evident with the present survey. This review focuses on the methods adopted using stem cells for heart diseases and outcomes that are generated so far with an idea to determine the best therapeutic possibility in order to fulfill the present demand. | Joseph C Bilgimol Subbareddy Ragupathi Lakshmanan Vengadassalapathy Nathan S Senthil Kali-muthu Selvakumar M Ganesan Sadananda Rao Manjunath | 2015 | World Journal of Stem Cells2015，7，8： | 6 |
| 3 | Long-term outcome of gastric access loop in hepaticojejunostomy显示文摘BACKGROUND:The incidence of hepaticojejunostomy stricture is 4%-10% in experienced centres. Many access loops have been designed and used to facilitate endoscopic intervention for this complication of hepaticojejunostomy. In this study, we investigated the effectiveness and safety of gastric access loop. METHODS:A retrospective analysis was conducted on 13 patients who had undergone hepaticojejunostomy with gastric access loop between June 1999 and September 2003. Eleven patients were followed up for a mean period of 51 months (range 20-81 months). Two patients were lost to follow up. RESULTS:On follow-up, 8 patients had patent jejuno- gastrostomy (end to side anastomosis between Roux loop of jejunum and stomach) and hepaticojejunostomy. Three patients developed stricture of jejunogastrostomy at 41 months, 63 months and 81 months of follow-up. Among these 3 patients, one also had hepaticojejunostomy stricture. In the patient with hepaticojejunostomy stricture, dilatation of jejunogastrostomy stricture was attempted but failed. None of the patients had any evidence of bile gastritis/cholangitis. There was no procedure related morbidity/mortality. CONCLUSIONS:Further studies involving large numbers of patients are required before wide application of gastric access loop in hepaticojejunostomy though it is a safer option than percutaneous transhepatic manipulations or revision surgery. | Eswaran Selvakumar Shanmugasundaram Rajendran Tirupporur G. Balachandar Devy Gounder Kannan Satyanesan Jeswanth Palaniappan Ravichandran Rajagopal Surendran | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，2： | 6 |
| 4 | Synthesis of silver nanoparticles using Acalypha indica leaf extracts and its antibacterial activity against water borne pathogens显示文摘 | C. Krishnaraj E.G. Jagan S. Rajasekar P. Selvakumar P.T. Kalaichelvan N. Mohan | 2009 | Colloids and Surfaces B: Biointerfaces2009，，1： | 4 |
| 5 | The effect of leaves extracts of Clitoria ternatea Linn against the fish pathogens显示文摘Objective:To investigate the antimicrobial activity of Clitoria ternatea(C.ternatea) against the fish pathogens viz.,Pseudomonas aeruginosa(P.aeruginosa),Escherichia coli(E.coli),Klebsiella pneumonia(K.pneumonia),Bacillus subtilis(B.subtilis),Aeromonas formican(A.formicans)s, Aeromonas hydrophila(A.hydrophila) and Streptococcus agalactiae(S.agalactiae )isolated from diseased Tilapia(Oreochromis niloticus).Methods:The extracts of C.ternatea was tested against P.aeruginosa,E.coli,K.pneumonia,B.subtilis,A.formicans,A.hydrophila and S.agalactiae by the agar well diffusion method.Results:Different extracts of C.ternatea showed inhibitory effects against P.aeruginosa,E.coli,K.pneumonia,B.subtilis,A.formicans,A.hydrophila and S. agalactiae.Ethyl acetate extracts of C.ternatea showed maximum of zone of inhibition against A. formicans(18 mm),A.hydrophilia(19 mm),B.subtilis(19 mm) and P.aeruginosa(21 mm) next to that ethanol extract of C.ternatea showed A.formicans(18 mm) and E.coli(14 mm) followed by Acetone extract showed maximum zone of inhibition S.agalactiae(19 mm) and K.pneumonia(17 mm).Conclusions:The antimicrobial activities of all the four plant extracts are comparable and their potential as alternative in the treatment of infectious by these microorganisms was present in the fish.Susceptibility testing is conducted on isolates using drugs selected on the basis of their importance to human medicine and use in fish production. | Selvamaleeswaran Ponnusamy Wesely Ebenezer Gnanaraj Johnson Marimuthu Antonisamy Velusamy Selvakumar Jeyakumar Nelson | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，9： | 4 |
| 6 | Watershed Prioritization of Palar Sub-watershed Based on the Morphometric and Land Use Analysis显示文摘Morphometric analysis is an indispensable tool for hydrological investigation that involves the development and management of drainage basin. This study characterizes the micro watersheds in the Palar sub-watershed using morphometric analysis and assesses its risk by land use and land cover features in a particular micro watershed. Palar sub-watershed is divided into 6 micro watersheds for prioritization based on morphometric and land use analysis. Several morphometric parameters(linear, shape and relief)are determined from the drainage map; ranks are assigned based on their capacity to induce erodability and degradation. Final ranking is based on the composite index calculated from the sum of the ranks of each morphometric parameter. Morphometric analysis reveals micro watersheds 5 and 6 as most susceptible and 2 and 3 as low susceptible. Land use is mapped using IRS ID LISS III satellite data. The risk in terms of watershed degradation involved to each micro watershed is based on the ranks of each land use feature, obtained from a similar composite index as that of morphometric analysis. Land use analysis shows that micro watersheds 2 and 4 fall under high priority category while 5 and 6 under low priority category. Integration of the morphometric and land use analysis shows that only micro watershed 1 falls under the same category in both analyses. Control measures are suggested to contain degradation depending on its specific land use pattern and morphometric features. This study can be used to prepare a comprehensive watershed plan for the development or for planning resource conservation strategies, by integrating land use features with the drainage characteristics of the region, in particular for a hill ecosystem as the prioritization is at micro level. | Evangelin Ramani SUJATHA Radhakrishnan SELVAKUMAR Balasubramaniam RAJASIMMAN | 2014 | Journal of Mountain Science2014，11，4： | 2 |
| 7 | Local outlier factor and stronger one class classifier based hierarchical model for detection of attacks in network intrusion detection dataset显示文摘 | Alampallam Ramaswamy VASUDEVAN Subramanian SELVAKUMAR | 2016 | Frontiers of Computer Science2016，10，4： | 2 |
| 8 | Thermal, electrical and wear be-havior of sintered Cu-W nanocomposite显示文摘 | Selvakumar N Vettivel S C | 2013 | Materials and De-sign2013，46，4： | 1 |
| 9 | Profile design considerations for minimizing base transit time in SiGe HBTs for all levels of injection before onset of Kirk effect 显示文摘 | KWOK K H SELVAKUMAR C R | 2001 | IEEE Tran Elec Dev2001，48，8： | 1 |
| 10 | Dynamic caching for semantic o- riented adaptive search in unstructured P2P networks 显示文摘 | Ramachandran G Selvakumar K | 2014 | Asian Journal of Information Technology2014，13，3： | 1 |
| 11 | Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4translocation in heart muscle显示文摘 | HU X SELVAKUMAR P | 2004 | Am J Physiol Endocrinol Metab2004，287，5： | 1 |
| 12 | Alternative techniques for arterialization in multivisceral grafting 显示文摘 | Lodge JP Pollard SG Selvakumar S | 1997 | Transplant Proc1997，29，3： | 1 |
| 13 | Syn- thesis, SAR, and antibacterial activity of novel oxazo- lidinone analogues prossessing urea functionality 显示文摘 | Selvakumar N Rajulu G G Reddy K C S | 2008 | bioorg Med Chem Lett2008，18，2： | 1 |
| 14 | Biolarvicidal activity of extracellular metabolites of the keratinophilic fungus Triehophyton mentagrophytes against arvae of Aedes aegypti-a major vector for Chikungunya and dengue显示文摘 | Murugesan A G Prabu C S Selvakumar C | 2009 | FOLIA MICROBIOLOGICA2009，54，3： | 1 |
| 15 | A watershed-scale design optimization model for stormwater best management practices 显示文摘 | Lee J G Selvakumar A Alvi K | 2012 | Environmental Modelling & Software2012，37，： | 1 |
| 16 | A new particle swarm optimization solution to nonconvex e- conomic dispatch problems 显示文摘 | SELVAKUMAR A I THANUSHKODI K | 2007 | IEEE Transactions on Power Systems2007，22，1： | 1 |
| 17 | Electroless Ni- Co- P ternary alloy deposits:preparation and characteristics 显示文摘 | Narayanan T S N S Selvakumar S Stephen A | 2003 | Surface and Coatings Technology2003，172，： | 1 |
| 18 | Nano RNA aptamer wire for analysis of vitamin B-12显示文摘 | Selvakumar L S Thakur M S | 2012 | Analytical Biochemistry2012，427，2： | 1 |
| 19 | Reprod lipoic acid ameliorates adriamycin-induced testicular mitochondriopathy显示文摘 | Prahalathan C Selvakumar E Varalakshmi P | 2005 | Toxicol2005，20，1： | 1 |
| 20 | Comparisong of DNA sequencing,PCR-SSCP and PhaB assays with indirect sensitivity testing for detection of rifampicin resistance in mycobacterium tuberculosis显示文摘 | SELVAKUMAR N KUMAR V | 2003 | Int J Tuberc Lung Dis2003，7，7： | 1 |
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