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| 1 | Leukemia:研究鉴定出与34种AML白血病亚群相关联的基因突变显示文摘针对成年急性髓细胞白血病(acute myeloid leukemia,AML)患者的一项新的大型研究将80种癌症相关基因突变与5种AML亚型相关联。这5种AML亚型可通过特异性的染色体异常加以确定。在未来,这些发现可能有助指导基因突变测试和治疗决策。 | A-K Eisfeld K Mrózek J Kohlschmidt D Nicolet S Orwick C J Walker K W Kroll J S Blachly A J Carroll J E Kolitz B L Powell E S Wang R M Stone A de la Chapelle J C Byrd C D Bloomfield | 2017 | 现代生物医学进展2017，17，15： | 7 |
| 2 | Proteinase inhibition of the detection of Listeria monocytogenes in milk using the polymerase chain reaction 显示文摘 | Powell H A Gooding C M Garrett S D | 1994 | Lett Appl Microbiol1994，18，： | 1 |
| 3 | Pilot fatigue in short-haul operations : effects of number of sectors, duty length, and time of day显示文摘 | Powell D M C Spencer M B Holland D | 2007 | Aviation Space and Environmental Medicine2007，78，7： | 1 |
| 4 | Proteinase inhibition of the detection of Listeria monocytogenes in milk using the polymerase chain reaction显示文摘 | Powell H A Gooding C M Garrett S D | 1994 | Letters in Applied Microbiology1994，18，1： | 1 |
| 5 | Effect of LX4211 on glucose homeostasis and body composition in preclinical models 显示文摘 | Powell D R DaCosta C M Smith M | 2014 | J Pharmacol Exp Ther2014，350，2： | 1 |
| 6 | Barriers to supply chain information integration:SMEs adrift of eLands显示文摘 | Harland C M Caldwell N D Powell P | 2007 | Journal of Operations Management2007，25，6： | 1 |
| 7 | Applicability of rare earth element oxides as a sediment tracer for coarse-textured soils 显示文摘 | Kimoto A Nearing M A Zhang X C Powell D M | 2006 | Catena2006，65，： | 1 |
| 8 | Seafloor constructions on the reconstruction of Gondwanaland显示文摘 | Veevers J J Powell C M Johnson B D | 1980 | Earth and Planetary Science Letters1980，51，： | 1 |
| 9 | Indoor air quality in typical temperate zone Australian dwellings显示文摘 | Molloy S B Cheng M Galbally I E Keywood M D Lawson S J Powell J C Gillett R Dunne E Selleck P W | 2012 | Atmospheric Environment2012，54，： | 1 |
| 10 | Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice显示文摘 | POWELL W C KNOX J D NAVRE M | 1993 | Cancer Res1993，53，12： | 1 |
| 11 | The role played byenvironmental factors in the integration of a transfer station in amunicipal solid waste management system 显示文摘 | Bovea M D Powell J C Gallardo A | 2007 | WasteManagement2007，27，4： | 1 |
| 12 | On the automatic activation of attitudes 显示文摘 | Fazio R Sanbonmatsu D Powell M C | 1986 | Journal of Personality and Social Psychology1986，50，： | 1 |
| 13 | The watchdog technique for forcing convergence in algorithm for constrained optimization显示文摘 | CHAMBERLAIN R M POWELL M J D LEMARECHAL C | | 0，，16： | 1 |
| 14 | Influence of sources on plutonium mobility and oxidation state transformations in vadose zone sediments 显示文摘 | Kaplan D I Powell B A Duff M C | 2007 | Environmental Science and Technology2007，41，21： | 1 |
| 15 | The Lewis Thrust/Rocky Mountain trench fault system in Northwest Montana,USA:an example of negative inversion tectonics显示文摘 | POWELL C M WILLIAMS G D | 1989 | Geol Society Spec Pubis1989，44，： | 1 |
| 16 | Influence of sources on plutonium mobility and oxidation state transformations in vadose zone sediments 显示文摘 | Kaplan D I Powell B A Duff M C | 2007 | Environmental Science and Technology2007，41，21： | 1 |
| 17 | Seafloor constructions on the reconstruction of Gondwanaland显示文摘 | Veevers J J Powell C M Johnson B D | 1980 | Earth and Planetary Science Letters1980，51，： | 1 |
| 18 | Expression of the metallopro-teinases matrilysis in Dn-145 cells increasestheir invasive poteontial insevere combined immunodeficient mice显示文摘 | POWELL W C KNOX J D NAVRE M | 1993 | Cancer Res1993，53，： | 1 |
| 19 | Medication beliefs predict medication adherence in ambulatory patients with decompensated cirrhosis显示文摘AIM To investigate the impact of medication beliefs, illness perceptions and quality of life on medication adherence in people with decompensated cirrhosis.METHODS One hundred adults with decompensated cirrhosis completed a structured questionnaire when they attended for routine outpatient hepatology review. Measures of self-reported medication adherence(Morisky Medication Adherence Scale), beliefs surrounding medications(Beliefs about Medicines Questionnaire), perceptions of illness and medicines(Brief Illness Perception Questionnaire), and quality of life(Chronic Liver Disease Questionnaire) were examined. Clinical data were obtained via patient history and review of medical records. Least absolute shrinkage and selection operator and stepwise backwards regression techniques were used to construct the multivariable logistic regression model. Statistical significance was set at alpha = 0.05.RESULTS Medication adherence was ' High ' in 42 % o f participants, 'Medium' in 37%, and 'Low' in 21%. Compared to patients with 'High' adherence, those with 'Medium' or 'Low' adherence were more likely to report difficulty affording their medications(P < 0.001), lower perception of treatment helpfulness(P = 0.003) and stronger medication concerns relative to medication necessity beliefs(P = 0.003). People with 'Low' adherence also experienced greater symptom burden and poorer quality of life, including more frequent abdominal pain(P = 0.023), shortness of breath(P = 0.030), and emotional disturbances(P = 0.050). Multivariable analysis identified having stronger medication concerns relative to necessity beliefs(Necessity-Concerns Differential ≤ 5, OR = 3.66, 95%CI: 1.18-11.40) and more frequent shortness of breath(shortness of breath score ≤ 3, OR = 3.87,95%CI: 1.22-12.25) as independent predictors of 'Low'adherence.CONCLUSION The association between 'Low' adherence and patients having strong concerns or doubting the necessity or helpfulness of their medications should be explored further given the clinical relevance. | Kelly L Hayward Patricia C Valery Jennifer H Martin Antara Karmakar Preya J Patel Leigh U Horsfall Caroline J Tallis Katherine A Stuart Penny L Wright David D Smith Katharine M Irvine Elizabeth E Powell W Neil Cottrell | 2017 | World Journal of Gastroenterology2017，23，40： | 1 |
| 20 | Birth, morphologic, and blood characteristics of free - ranging white - tailed deer neonates 显示文摘 | POWELL M C DELGIUDICE G D | 2005 | J Wildl Dis2005，41，1： | 1 |
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