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	题名	作者	年代	出处	被引量
1	Pituitary hormone circadian rhythm alterations in cirrhosis patients with subclinical hepatic encephalopathy显示文摘AIM:To analyze pituitary hormone and melatonin circadian rhythms, and to correlate hormonal alterations with clinical performance, hepatic disease severity and diagnostic tests used for the detection of hepatic encephalopathy in cirrhosis. METHODS:Twenty-six patients with cirrhosis were enrolled in the study. Thirteen patients hospitalized for systemic diseases not affecting the liver were included as controls. Liver disease severity was assessed by the Child-Pugh score. All patients underwent detailed neurological assessment, electroencephalogram (EEG), brain magnetic resonance imaging (MRI), assays of pituitary hormone, cortisol and melatonin, and complete blood chemistry evaluation. RESULTS: Pituitary hormone and melatonin circadian patterns were altered in cirrhosis patients without clinical encephalopathy. Circadian hormone alterations were different in cirrhosis patients compared with controls. Although cortisol secretion was not altered in any patient with cirrhosis, the basal cortisol levels were lowand correlated with EEG and brain MRI abnormalities. Melatonin was the only hormone associated with the severity of liver insufficiency. CONCLUSION: Abnormal pituitary hormone and melatonin circadian patterns are present in cirrhosis before the development of hepatic encephalopathy. These abnormalities may be early indicators of impending hepatic encephalopathy. Factors affecting the human biologic clock at the early stages of liver insufficiency require further study.	Dimitrios Velissaris Menelaos Karanikolas Andreas Kalogeropoulos Ekaterini Solomou Panagiotis Polychronopoulos Konstantinos Thomopoulos Chrissoula Labropoulou-Karatza	2008	World Journal of Gastroenterology2008，14，26：	9
2	Expression of bcl-2protein in bronchoalveolar lavage cell populations from patients with idiopathic pulmonary fibrosis 显示文摘	Mermigkis C M Tsakanika K Polychronopoulos V	2001	Acta Cyto12001，45，6：	1
3	A review on ox- aliplatin-induced peripheral nerve danmge显示文摘	Argyriou AA Polychronopoulos P Iconomou G	2008	Cancer Treat Rev2008，34，4：	1
4	Acute inter-stitial pneumonia显示文摘	Bouros D Nicholson A C Polychronopoulos V	2000	Eur Respir J2000，15，2：	1
5	The role of Mediterranean diet in the epidemiology of metabolic syndrome; Converting epidemiology to clinical practice显示文摘	Panagiotakos DB Polychronopoulos E	2005	Lipids Health Dis2005，4，1：	1
6	Stochastic shortest path problems with recourse显示文摘	George H Polychronopoulos John N Tsitsiklis	1996	Networks (S0028-3045)1996，27，2：	1
7	Clinical and elec- trophysiologieal features of peripheral neuropathy induced hy adminis- tration of cisplatin plus paclitaxel-based chemotherapy显示文摘	Argyriou AA Polychronopoulos P Koutras A	2007	Eur J Cancer Care (Engl)2007，16，3：	1
8	A review on oxaliplatin-induced peripheral nerve damage显示文摘	Argyriou AA Polychronopoulos P Iconomou G	2008	Cancer Treatment Reviews2008，34，：	1
9	Organi- zing pneumonia显示文摘	Drakopangiotakis F Polychronopoulos V Judson MA	2008	Am J Med sei2008，335，1：	1
10	Airway involvement in Wegener's granulomatosis显示文摘	Polychronopoulos VS Prakash UB Goblin JM		0，，04：	1
11	Airway involve- ment in sarcoidosis显示文摘	POLYCHRONOPOULOS V S PRAKASH U B S	2009	Chest J2009，136，5：	1
12	The role of Mediterranean diet in the epidemiology of metabolic syndrome; converting epidemiology to clinical practice显示文摘	Panagiotakos D B Polychronopoulos E	2005	Lipids Health Dis2005，4，1：	1
13	Sensor fusion for predicting vehi- cles' path for collision avoidance systems显示文摘	Polychronopoulos Aris Tsogas Manolis Amditis Angelos J	2007	IEEE Transactions on Intelligent Transportation Systems2007，8，3：	1
14	Comparative study of accelerated solvent extraction and super- critical fluid extraction of total phenolics and flavonoids from Sideritis raeseri subsp attica and study of antioxidant activity 显示文摘	Papaefstathiou G Polychronopoulos P Aligiannis N	2008	Planta Medica2008，74，9：	1
15	Organizing pneumonia显示文摘	DRAKOPANAGIOTAKIS F POLYCHRONOPOULOS V JUDSON MA	2008	Am J Med Sci2008，335，：	1
16	Airway involvement in sarcoidosis 显示文摘	Polychronopoulos VS Prakash UB	2009	Chest2009，136，：	1
17	Ap- optosis in lung injury and fibrosis显示文摘	Drakopanagiotakis F Xifteri A Polychronopoulos V	2008	Eur Respir J2008，32，6：	1
18	Incidence and characteristics of peripheral neuropathy during oxaliplatin-based chemotherapy for metastatic colon cancer显示文摘	Argyriou Andreas A Polychronopoulos Panagiotis Iconomou Gregoris	2007	Acta oncologica2007，46，8：	1
19	Organizing pneumonia显示文摘	D rakopanagiotakis F Polychronopoulos V Judson MA	2008	Am J Med Sci2008，335，1：	1
20	A review on oxaliplatin-induced peripheral nerve damage 显示文摘	Argyriou Andreas A Polychronopoulos Panagiotis Iconomou Gregoris	2008	Cancer treatment reviews2008，34，4：	1

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