|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Epidural anesthesia improves pancreatic perfusion and decreases the severity of acute pancreatitis显示文摘AIM: To study the safety of epidural anesthesia(EA),its effect on pancreatic perfusion and the outcome of patients with acute pancreatitis(AP).METHODS: From 2005 to August 2010,patients with predicted severe AP [Ranson score ≥ 2,C-reactive protein > 100 or necrosis on computed tomography(CT)] were prospectively randomized to either a group receiving EA or a control group treated by patientcontrolled intravenous analgesia. Pain management was evaluated in the two groups every eight hours using the visual analog pain scale(VAS). Parameters for clinical severity such as length of hospital stay,use of antibiotics,admission to the intensive care unit,radiological/clinical complications and the need for surgical necrosectomy including biochemical data were recorded. A CT scan using a perfusion protocol was performed on admission and at 72 h to evaluate pancreatic blood flow. A significant variation in blood flow was defined as a 20% difference in pancreatic perfusion between admission and 72 h and was measured in the head,body and tail of the pancreas.RESULTS: We enrolled 35 patients. Thirteen were randomized to the EA group and 22 to the control group. There were no differences in demographic characteristics between the two groups. The Balthazar radiological severity score on admission was higher in the EA group than in the control group(mean score 4.15 ± 2.54 vs 3.38 ± 1.75,respectively,P = 0.347) and the median Ranson scores were 3.4 and 2.7 respectively(P = NS). The median duration of EA was 5.7 d,and no complications of the epidural procedure were reported. An improvement in perfusion of the pancreas was observed in 13/30(43%) of measurements in the EA group vs 2/27(7%) in the control group(P = 0.0025). Necrosectomy was performed in 1/13 patients in the EA group vs 4/22 patients in the control group(P = 0.63). The VAS improved during the first ten days in the EA group compared to the control group(0.2 vs 2.33,P = 0.034 at 10 d). Length of stay and mortality were not statistically different between the 2 groups(26 d vs 30 d,P = 0.65,and 0% for both respectively).CONCLUSION: Our study demonstrates that EA increases arterial perfusion of the pancreas and improves the clinical outcome of patients with AP. | Samira M Sadowski Axel Andres Philippe Morel Eduardo Schiffer Jean-Louis Frossard Alexandra Platon Pierre-Alexandre Poletti Leo Bühler | 2015 | World Journal of Gastroenterology2015，21，43： | 21 |
| 2 | Aberrant Wnt/β-Catenin Pathway Activation in Idiopathic Pulmonary fibrosis显示文摘 | Chilosi M Poletti V Zamo A | 2003 | Am J Pathol2003，162，5： | 1 |
| 3 | Bronchiolitis obliterans with organizing pneumonia (BOOP), presenting as a ring-shaped opacity at HRCT (the atoll sign): a case report显示文摘 | Zompatori M Poletti V Battista G | 1999 | Radiol Med (Torino)1999，97，4： | 1 |
| 4 | The effect of risk perception on the 2009 H1N1 pandemic influenza dynamics显示文摘 | Poletti P Ajelli M Merler S | | 0，，02： | 1 |
| 5 | Low triiodothyronine and exercise capacity in heart failure显示文摘 | Fontana M Passino C Poletti R | 2012 | Int J Cardiol2012，154，2： | 1 |
| 6 | Aberrant Wnt/p-catenin pathway activationin idiopathic pulmonary fibm-sis显示文摘 | Chilosi M Poletti V Zamb A | 2003 | Am J Pathol2003，162，5： | 1 |
| 7 | Diagnostic invasive procedures in diffuse infiltrative lung diseases显示文摘 | Poletti V Chilosi M Olivieri D | 2004 | Respiration2004，71，： | 1 |
| 8 | Diffuse panbronchiolitise显示文摘 | Poletti V Casoni G Chilosi M | 2006 | Eur Respir J2006，28，： | 1 |
| 9 | Study of the hot de- formation behaviour in Ti-5A1-5Mo-5V-3Cr-IZr 显示文摘 | Warchomicka F Poletti C Stockinger M | 2011 | Materials Science and Engineering : A2011，528，28： | 1 |
| 10 | The effect of native Al2O3 skin disruption on properties of fine AI powder compacts显示文摘 | BALOG M POLETTI C SIMANCIK F | 2011 | Journal of Alloys and Compounds2011，509，1： | 1 |
| 11 | Law of mixture used to model the flow behavior of a duplex stainless steel at high temperatures显示文摘 | MOMENI A DEHGHANI K POLETTI M C | 2013 | Materials Chemistry and Physics2013，139，23： | 1 |
| 12 | 显示文摘 | Romagna M Gasponi A | 1995 | Monaldi Arch Chest Dis1995，50，3： | 1 |
| 13 | Traumatic injuries: role of imaging in the management of the polytrauma victim (conserva-tive expectation)显示文摘 | Poletti PA Wintermark M Schnyder P | 2002 | Eur Radiol2002，12，： | 1 |
| 14 | Three-dimensional surround sound systems based on spherical harmonics显示文摘 | Poletti M A | 2005 | Journal of the Audio Engineering Society2005，53，11： | 1 |
| 15 | Aberrant Wnt/betacatenin pathway activation in idiopathic pulmonary fibrosis显示文摘 | Chilosi M Poletti V Zamo A | 2003 | Am J Pathol2003，162，5： | 1 |
| 16 | Low triiodothyronine and exercise capacity in heart failure显示文摘 | Fontana M Passino C Poletti R | 2012 | Int J Cardiol2012，154，2： | 1 |
| 17 | Behavioral and psycho- logical symptoms of dementia: factor analysis and relationship with cognitive impairment显示文摘 | Poletti M Nuti A Cipriani G | 2013 | Eur Neurol2013，69，2： | 1 |
| 18 | Microstructure development in hot deformed AA6082 显示文摘 | Poletti C Rodriguez-Hortala M | 2011 | Mater Sci Eng A2011，528，： | 1 |
| 19 | Deformation mechanism- sin the near- β titanium alloy Ti -55531 显示文摘 | Dikovits M Poletti C Warchomicka F | 2013 | Metallurgical and Materials Transactions A2013，44，3： | 1 |
| 20 | Effects of recombinant human granulocyte colony-stimulating factor (rhG-CSF) on murine bone marrow and spleen erythropoiesis 显示文摘 | Barrios L Agustini M I Poletti O H | 1998 | Acta Physiol Pharmacol Ther Latinoam1998，48，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员