|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effects of partial portal vein arterialization on the hilar bile duct in a rat model显示文摘BACKGROUND: Liver revascularization is frequently required during the enlarged radical operation for hilar cholangio carcinoma involving the hepatic artery. Researchers have carried out a number of experiments applying partial porta vein arterialization (PVA) in clinical practice. In this study we aimed to establish a theoretical basis for clinical application o partial PVA and to investigate the effects of partial PVA on ra hilar bile duct and hepatic functions. METHODS: Thirty rats were randomly and equally assigned into 3 groups: control (group A), hepatic artery ligation+bile duct recanalization (group B), and partial PVA+bile duc recanalization (group C). Proliferation and apoptosis o rat hilar bile duct epithelial cells, arteriolar counts of the peribiliary plexus (PBP) of the bile duct wall, changes in serum biochemistry, and pathologic changes in the bile duc were assessed 1 month after operation. RESULTS: The proliferation of hilar bile duct epithelial cells in group B was greater than in groups A and C (P<0.01). No apoptotic hilar bile duct epithelial cells were detected in any of the groups. The PBP arteriolar counts of the hilar bile duc wall were similar in groups A and C (P>0.05), but the coun was lower in group B than in group A (P<0.01). No statistically significant differences in alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and albumin were found in the 3 groups. The gamma-glutamyltransferase value was higher in group B than in groups A and C (P<0.01) The hepatic tissues of groups A and C showed no significan abnormality. Chronic inflammatory changes in the hilar bile duct walls were observed only in group B. CONCLUSION: Partial PVA can restore the arterial blood supply of the hilar bile duct and significantly extenuate the injury to hilar bile duct epithelial cells resulting from hepatic artery ligation. | Shao-Hua Guo, Chong-Hui Li,Yong-Liang Chen, Jian-Ning Song,Ai-Qun Zhang and Cheng Zhou Department of Hepatobiliary Surgery (Guo SH, Li CH, Chen YL, Song JN, Zhang AQ and Zhou C) and Department of Surgical Oncology (Guo SH), General Hospital of PLA, Beijing 100853, China | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，5： | 8 |
| 2 | Phylogeography of the Atlantic bonito (Sarda sarda) in the northern Mediterranean:the combined effects of historical vicariance,population expansion,secondary invasion,and isolation by distance显示文摘 | Vinas J Bremer J A Pla C | 2004 | Molecular Phylogenetics and Evolution2004，33，： | 1 |
| 3 | Com- position and functional properties of enriched fiber prod- ucts obtained from pumpkin ( Cucurbita moschata Duch- esne ex Poiret) 显示文摘 | de Escalada Pla M F Ponce N M Stortz C A | 2007 | LWT-Food Science and Technolo- gy2007，40，7： | 1 |
| 4 | Genetic structure of the European anchovy, Engraulis e ncrasicolus, in the north-west Mediterranean 显示文摘 | TUDELA S GARCfA-MARfN J L PLA C | 1999 | J Exp Mar Biol Ecol1999，234，1： | 1 |
| 5 | Sensitivity of osteocytes to biomechanical stress in vitro 显示文摘 | Klein-Nulend J Van Der Plas A Semeins C M | 1995 | FASEB J1995，9，： | 1 |
| 6 | The predictive value of cerebrospinal fluid Epstein-Barr viral load as a marker of primary central nervous system lymphoma in HIV-infected persons显示文摘 | Corcoran C Rebe K van der Plas H | 2008 | J Clin Virol2008，42，4： | 1 |
| 7 | Petrologic and stable isotope constraints on hydrothermal alteration and serpentinization of the EPR shallow mantle at Hess Deep (Site 895) 显示文摘 | FRUH-GREEN G L PLAS A LECUYER C | 1996 | Proceedings of Ocean Drilling Program: Scientific Results1996，147，： | 1 |
| 8 | Modelling and simulation of batch and semi-batch emulsion copolymerization of styrene and butyl acrylate显示文摘 | Ginsburger E Pla F Fonteix C | 2003 | ChemEngin Sci2003，58，19： | 1 |
| 9 | Genetic structure of the European anchovy, Engraulis encrasicolus, in the northwest Mediterranean 显示文摘 | Tudela S Garca-Marn J L Pla C | 1999 | Journal of Experimental Marine Biology and Ecology1999，234，： | 1 |
| 10 | Deletion of the last two exons of the mitochondrial nad7 gene results in lack of the NAD7 polypeptide in a Nicotiana sylvestris CMSmutant显示文摘 | Pla M Mathieu C De Paepe R Chetrit P Vedel P | 1995 | Mol Gen Genet1995，248，： | 1 |
| 11 | The Shol adaptor protein links oxidative stress to morphogenesis and cell wall biosynthesis in the fungal pathogen Candida albicans 显示文摘 | Nombela C Pla J | 2005 | Mol Cell Biol2005，25，10： | 1 |
| 12 | Induced expression of the Candida albicans multidrug resistance gene CDR1 in response to fluconazole and other antifungals 显示文摘 | Gil C Pla J | 1998 | Yeast1998，14，： | 1 |
| 13 | Akt- directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival显示文摘 | Rathmell J C Fox C J Plas D R | 2003 | Mol Cell biol2003，23，20： | 1 |
| 14 | Modelling and Simulation of Batch and Semi-batch Emulsion Copolymerization of Styrene and Butyl acrylate 显示文摘 | Ginsburger E Pla F Fonteix C | 2003 | Chemical Engineering Science2003，58，19： | 1 |
| 15 | Combinations of maggot excretions/secretions and antibiotics are effective a- gainst Staphylococcus aureus biofilms and the bacteria derived therefrom显示文摘 | Van Der Plas M Dambrot C Dambrot C | 2010 | Antimicrob Chemother2010，65，5： | 1 |
| 16 | The Shol adaptor protein links oxidative stress to morphogenesis and cell wall biosynthesis in the fungal pathogen Candida aJbicans 显示文摘 | Roman E Nombela C Pla J | 2005 | Mol Cell Biol2005，25，10： | 1 |
| 17 | Fluorescence detection of bladder tumors with 5-aminolevulinic acid 显示文摘 | Riedl C Plas E Pfluger H | 1999 | J Endourol1999，13，： | 1 |
| 18 | Deletion of the last two exons of the mitochondriM nad7 gene results in lack of the NAD7 polypeptide in a Nicotiana sylvestris CMS mutant显示文摘 | Pla M Mathieu C De Paepe R et M | 1995 | Mol Gen Genet1995，248，： | 1 |
| 19 | Silent casualties from themeasles outbreak in South Africa显示文摘 | Albertyn C van der Plas H Hardie D | 2011 | S Afr Med J2011，101，： | 1 |
| 20 | Effect of raindrop impact and its relationship with aggregate stability to different disaggregation forces显示文摘 | RAMOS M C NACCI S PLA I | 2003 | CATENA2003，53，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员