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| 1 | Relationship of MTHFR gene polymorphisms with renal and cardiac disease显示文摘AIM: To investigate the effects of different methylenetetrahydrofolate reductase(MTHFR) 677C>T gene polymorphism and hyperhomocysteinemia for the development of renal failure and cardiovascular events, which are controversial.METHODS: We challenged the relationship, if any, of MTHFR 677C>T and MTHFR 1298A>C polymorphisms with renal and heart function. The present article is a reappraisal of these concepts, investigating within a larger population, and including a subgroup of dialysis patients, if the two most common MTHFR polymorphisms, C677 T and A1298 C, as homozygous, heterozygous or with a compound heterozygous state, show different association with chronic renal failure requiring hemodialysis. MTHFR polymorphism could be a favorable evolutionary factor, i.e., a protective factor for many ominous conditions, like cancer and renal failure. A similar finding was reported in fatty liver disease in which it is suggested that MTHFR polymorphisms could have maintained and maintain their persistence by an heterozygosis advantage mechanism. We studied a total of 630 Italian Caucasian subject aged 54.60 ± 16.35 years, addressing to the increased hazard of hemodialysis, if any, according to the studied MTHFR genetic polymorphisms. RESULTS: A favorable association with normal renal function of MTHFR polymorphisms, and notably of MTHFR C677 T is present independently of the negative effects of left ventricular hypertrophy, increased IntraRenal arterial Resistance and hyperparathyroidism. CONCLUSION: MTHFR gene polymorphisms could have a protective role on renal function as suggested by their lower frequency among our dialysis patients in end-stage renal failure; differently, the association with left ventricular hypertrophy and reduced left ventricular relaxation suggest some type of indirect, or concurrent mechanism. | Francesca M Trovato Daniela Catalano Angela Ragusa G Fabio Martines Clara Pirri Maria Antonietta Buccheri Concetta Di Nora Guglielmo M Trovato | 2015 | World Journal of Nephrology2015，4，1： | 10 |
| 2 | Fabrication,microstructures,and optical properties of Yb:Lu_(2)O_(3) laser ceramics from co-precipitated nano-powders显示文摘The Yb:Lu_(2)O_(3)precursor made up of spherical particles was synthesized through the co-precipitation method in the water/ethanol solvent.The 5 at% Yb:Lu_(2)O_(3)powder is in the cubic phase after calcination at 1100℃ for 4 h.The powder also consists of spherical nanoparticles with the average particle and grain sizes of 96 and 49 nm,respectively.The average grain size of the pre-sintered ceramic sample is 526 nm and that of the sample by hot isostatic pressing grows to 612 nm.The 1.0 mm-thick sample has an in-line transmittance of 81.6%(theoretical value of 82.2%)at 1100 nm.The largest absorption cross-section at 976 nm is 0.96×1^(0-20)cm^(2) with the emission cross-section at 1033 nm of 0.92×10^(-20)cm^(2) and the gain cross sections are calculated with the smallest population inversion parameter β of 0.059.The highest slope efficiency of 68.7% with the optical efficiency of 65.1% is obtained at 1033.3 nm in quasi-continuous wave(QCW)pumping.In the case of continuous wave(CW)pumping,the highest slope efficiency is 61.0% with the optical efficiency of 54.1%.The obtained laser performance indicates that Yb:Lu_(2)O_(3)ceramics have excellent resistance to thermal load stresses,which shows great potential in high-power solid-state laser applications. | Ziyu LIU Guido TOCI Angela PIRRI Barbara PATRIZI Yagang FENG Jiabei WEI Feng WU Zhaoxiang YANG Matteo VANNINI Jiang LI | 2020 | Journal of Advanced Ceramics2020，9，6： | 4 |
| 3 | 共沉淀纳米粉体制备Yb:CaF2激光陶瓷及其性能研究(英文)显示文摘利用共沉淀法合成的粉体,通过真空烧结结合热压烧结后处理制备了掺镱的氟化钙透明陶瓷(Yb:CaF2)。在600℃预烧1 h,700℃热压烧结2 h制备的5at%Yb:CaF2透明陶瓷在1200 nm处的直线透射率达到92.0%。对陶瓷的显微结构、光谱特性和激光性能进行了测试和讨论。研究结果表明,陶瓷样品的显微结构均匀,平均晶粒尺寸为360 nm。此外,计算得到Yb:CaF2陶瓷在977nm处的吸收截面和1030nm处的发射截面分别为0.39×10–20和0.26×10–20cm2。最后,对Yb:CaF2陶瓷激光性能进行了表征,得到最大输出功率为0.9 W,最大斜率效率为23.6%。 | 韦家蓓 TOCI Guido PIRRI Angela PATRIZI Barbara 冯亚刚 VANNINI Matteo 李江 | 2019 | 无机材料学报2019，34，12： | 4 |
| 4 | 固体激光用Nd:Lu_(2)O_(3)透明陶瓷的制备和光学性能研究显示文摘Nd:Lu_(2)O_(3)材料由于具有高热导率、低声子能量和优异的光学特性而成为非常有前景的高功率固体激光器用的增益介质。但Lu_(2)O_(3)单晶的熔点超过2400℃,难以生长,而Lu_(2)O_(3)陶瓷既能在低温下制备,又具有与晶体相当的光学性质和激光性能从而备受关注。本研究制备了高透明的Nd:Lu_(2)O_(3)陶瓷并对其光学性质和激光性能进行探究。以共沉淀法制备的纳米粉体为原料,采用真空烧结结合热等静压(HIP)两步烧结法制备了1.0at%Nd:Lu_(2)O_(3)透明陶瓷。对制备的粉体、素坯和陶瓷的微结构进行了表征:HIP后处理的陶瓷平均晶粒尺寸是724.2nm。厚度为1.0mm的1.0at%Nd:Lu_(2)O_(3)透明陶瓷在1100 nm处的直线透过率是82.4%,样品在806 nm处的吸收截面为1.50×10^(-20)cm^(2),而根据荧光光谱计算得到的发射截面为6.5×10^(–20)cm^(2)。分别在878.8和895.6 nm波长激发下,1.0at%Nd:Lu_(2)O_(3)透明陶瓷(4)^F3/2→(4)^I11/2跃迁的平均荧光寿命均为169ms。当输出耦合镜的透过率TOC=2.0%时,退火后的1.0at%Nd:Lu_(2)O_(3)透明陶瓷获得了最大输出功率为0.47 W的准连续(QCW)激光输出,斜率效率为8.7%。本研究成功制备了显微结构均匀、高透明度的1.0at%Nd:Lu_(2)O_(3)陶瓷,并展示了其在固体激光增益介质领域的广阔应用潜力。 | 刘子玉 TOCI Guido PIRRI Angela PATRIZI Barbara 冯亚刚 陈肖朴 胡殿君 田丰 吴乐翔 VANNINI Matteo 李江 | 2021 | 无机材料学报2021，36，2： | 3 |
| 5 | Symptomatic pneumocephalus asso- ciated with lumbar dural tear and reverse trendelenburg posi- tioning: a case report and review of the literature 显示文摘 | Pirris SM Nottmeier EW | 2013 | Case Rep Neurol Med2013，2013，79： | 1 |
| 6 | The fluid mechanics of pulsed laser propulsion显示文摘 | Simons G A Pirri N A | 1977 | AIAA Journal1977，15，6： | 1 |
| 7 | Antimicrobial peptides: an overview of a promising class of therapeutics显示文摘 | Giuliani A Pirri G Nicoletto S | 2007 | Cent Eur J Biol2007，2，1： | 1 |
| 8 | Lifestyle interventions,insulin resistance,and renal artery stiffness in essential hypertension显示文摘 | TROVATO G M PIRRI C MARTINES G F | 2010 | Clin Exp Hypertens2010，32，： | 1 |
| 9 | A retrospective study of iliac crest bone grafting techniques with allograft reconstruction:do patients even know which iliac crest was harvested显示文摘 | Pirris SM Nottmeier EW Kimes S | 2014 | J Neurosurg Spine2014，21，4： | 1 |
| 10 | Towards a broader understanding of authority in student–teacher relationships显示文摘 | Gale Macleod James MacAllister Anne Pirrie | 2012 | Oxford Review of Education2012，，4： | 1 |
| 11 | Theory for momentum transfer to a surface with a high-power laser显示文摘 | Pirri A N | 1973 | The Physics of Fluids1973，16，9： | 1 |
| 12 | Synthesis and bio- logical characterisation of sirtuin inhibitors based on the tenovins 显示文摘 | McCarthy AR Pirrie L Hoilick JJ | 2012 | Bioorg Med Chem2012，20，5： | 1 |
| 13 | Plasma energy transfer to metal surfaces irradiated by pulsed lasers显示文摘 | Pirri A N Root R G P Wu K S | 1978 | AIAA J1978，16，12： | 1 |
| 14 | α-SiC:H films deposited by PECVD from silane+acetylene and silane+acetylene+hydrogen gas mixture显示文摘 | GIORGIS F PIRRI C F TRESSO E RAVA P | 1997 | Diamond and Related Materials1997，6，： | 1 |
| 15 | Synthesis of novel 60ullerene-flavonoid dyads显示文摘 | Maria D L Marcorin G L Pirri G | 2002 | Tetrahedron Letters2002，43，9： | 1 |
| 16 | Lipopeptides as anti-in- fectives : a practical perspective 显示文摘 | Pirri G Giuliani S Nicoletto S | 2009 | Central European Journal of Biology2009，4，3： | 1 |
| 17 | Antimicrobial peptides: an overview of a promising class of therapeutics显示文摘 | Giuliani A Pirri G Nicoletto S F | 2007 | Cent Eur J Biol2007，2，1： | 1 |
| 18 | 显示文摘 | Reitano R Foti G Pirri C F | 2001 | Materials Science and Engineering:C2001，15，12： | 1 |
| 19 | Risk factors at pretreat- ment predicting treatment-induced nausea and vomiting in Australian cancer patients A prospective, longitudi- nal,observational study显示文摘 | Pirri C Katris P Trotter J | 2011 | Support Care Cancer2011，19，10： | 1 |
| 20 | Physics fluid显示文摘 | PIRRI A N | 1976 | 16(9):1435-14401976，16，9： | 1 |
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