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| 1 | A red water occurrence in drinking water distribution systems caused by changes in water source in Beijing, China: mechanism analysis and control measures显示文摘 | Xiaojian ZHANG Zilong MI Yang WANG Shuming LIU Zhangbin NIU Pinpin LU Jun WANG Junnong GU Chao CHEN | 2014 | Frontiers of Environmental Science & Engineering2014,8,3: | 7 |
| 2 | Biostability in distribution systems in one city in southern China: Characteristics, modeling and control strategy显示文摘This study investigated the bacterial regrowth in drinking water distribution systems receiving finished water from an advanced drinking water treatment plant in one city in southern China. Thirteen nodes in two water supply zones with different aged pipelines were selected to monitor water temperature, dissolved oxygen(DO), chloramine residual, assimilable organic carbon(AOC), and heterotrophic plate counts(HPC). Regression and principal component analyses indicated that HPC had a strong correlation with chloramine residual. Based on Chick-Watson's Law and the Monod equation, biostability curves under different conditions were developed to achieve the goal of HPC 100 CFU/mL. The biostability curves could interpret the scenario under various AOC concentrations and predict the required chloramine residual concentration under the condition of high AOC level. The simulation was also carried out to predict the scenario with a stricter HPC goal( 50 CFU/mL) and determine the required chloramine residual. The biological regrowth control strategy was assessed using biostability curve analysis. The results indicated that maintaining high chloramine residual concentration was the most practical way to achieve the goal of HPC 100 CFU/mL. Biostability curves could be a very useful tool for biostability control in distribution systems. This work could provide some new insights towards biostability control in real distribution systems. | Pinpin Lu Xiaojian Zhang Chiqian Zhang Zhangbin Niu Shuguang Xie Chao Chen | 2014 | Journal of Environmental Sciences2014,26,2: | 7 |
| 3 | Ecological principle meets cancer treatment: treating children with acute myeloid leukemia with low-dose chemotherapy显示文摘Standard chemotherapy regimens for remission induction of pediatric acute myeloid leukemia(AML) are associated with significant morbidity and mortality. We performed a cohort study to determine the impact of reducing the intensity of remission induction chemotherapy on the outcomes of selected children with AML treated with a low-dose induction regimen plus granulocyte colony stimulating factor(G-CSF)(low-dose chemotherapy(LDC)/G-CSF). Complete response(CR) after two induction courses was attained in 87.0%(40/46) of patients receiving LDC/G-CSF. Post-remission therapy was offered to all patients, and included standard consolidation and/or stem cell transplantation. During the study period, an additional 94 consecutive children with AML treated with standard chemotherapy(SDC) for induction(80/94(85.1%) of the patients attained CR after induction Ⅱ, P = 0.953) and post-remission. In this non-randomized study, there were no significant differences in 4-year event-free(67.4 vs. 70.7%;P = 0.99)and overall(70.3 vs. 74.6%, P = 0.69) survival in the LDC/G-CSF and SDC cohorts, respectively. After the first course of induction, recovery of white blood cell(WBC) and platelet counts were significantly faster in patients receiving LDC/G-CSF than in those receiving SDC(11.5 vs. 18.5 d for WBCs(P < 0.001);15.5 vs. 22.0 d for platelets(P < 0.001)). To examine the quality of molecular response, targeted deep sequencing was performed. Of 137 mutations detected at diagnosis in 20 children who attained hematological CR after two courses of LDC/G-CSF(n = 9) or SDC(n = 11), all of the mutations were below the reference value(variant allelic frequency <2.5%) after two courses, irrespective of the treatment group. In conclusion, children with AML receiving LDC/G-CSF appear to have similar outcomes and mutation clearance levels, but significantly lower toxicity than those receiving SDC. Thus, LDC/G-CSF should be further evaluated as an effective alternative to remission induction in pediatric AML. | Yixin Hu Aili Chen Xinchang Zheng Jun Lu Hailong He Jin Yang Ya Zhang Pinpin Sui Jingyi Yang Fuhong He Yi Wang Peifang Xiao Xin Liu Yinmei Zhou Deqing Pei Cheng Cheng Raul C. Ribeiro Shaoyan Hu Qian-fei Wang | 2019 | National Science Review2019,6,3: | 3 |
| 4 | Research on Silicon-Based Terahertz Communication Integrated Circuits显示文摘With the increasing number of users and emerging new applications, the demand for mobile data traffic is growing rapidly. The limited spectrum resources of the traditional microwave and millimeter-wave frequency bands can no longer support the future wireless communication systems with higher system capacity and data throughput. The terahertz(THz) frequency bands have abundant spectrum resources, which can provide sufficient bandwidth to expand channel capacity and increase transmission data rate. In addition, with the rapid development of silicon-based semiconductor technology,its characteristic size keeps decreasing, and the radio frequency performance of active devices is gradually approaching the performance of III-V semiconductor technology. The realization of THz communication systems based on low-cost, high-stability, and easy-to-integrate silicon-based process has become a feasible solution. This review summarizes the reported silicon-based THz communication systems, as well as the key sub-circuit chips in these systems, including the local oscillator, power amplifier, low noise amplifier, on-chip antenna and transceiver chip, etc. | ZHOU Peigen CHEN Jixin TANG Siyuan YU Jiayang WANG Chen LI Huanbo LU Haiyan YAN Pinpin HOU Debin CHEN Zhe HONG Wei | 2022 | Chinese Journal of Electronics2022,31,3: | 0 |