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| 1 | Embolization of splenorenal shunt associated to portal vein thrombosis and hepatic encephalopathy显示文摘Hepatic encephalopathy(HE)is a cognitive disturbance characterized by neuropsychiatric alterations.It occurs in acute and chronic hepatic disease and also in patients with portosystemic shunts.The presence of these portosystemic shunts allows the passage of nitrogenous substances from the intestines through systemic veins without liver depuration.Therefore,the embolization of these shunts has been performed tocontrol HE manifestations,but the presence of portal vein thrombosis is considered a contraindication.In this presentation we show a cirrhotic patient with severe HE and portal vein thrombosis who was submitted to embolization of a large portosystemic shunt.Case report:a 57 years-old cirrhotic patient who had been hospitalized many times for persistent HE and hepatic coma,even without precipitant factors.She had a wide portosystemic shunt and also portal vein thrombosis.The abdominal angiography confirmed the splenorenal shunt and showed other shunts.The larger shunt was embolized through placement of microcoils,and the patient had no recurrence of overt HE.There was a little increase of esophageal and gastric varices,but no endoscopic treatment was needed.Since portosystemic shunts are frequent causes of recurrent HE in cirrhotic patients,portal vein thrombosis should be considered a relative contraindication to perform a shunt embolization.However,in particular cases with many shunts and severe HE,we found that one of these shunts can be safely embolized and this procedure can be sufficient to obtain a good HE recovery.In conclusion,we reported a case of persistent HE due to a wide portosystemic shunt associated with portal vein thrombosis.As the patient had other shunts,she was successfully treated by embolization of the larger shunt. | Letícia de Campos Franzoni Fábio Cardoso de Carvalho Rafael Gomes de Almeida Garzon Fábio da Silva Yamashiro Laís Augusti Lívia Alves Amaral Santos Mariana de Souza Dorna Júlio Pinheiro Baima Talles Bazeia Lima Carlos Antonio Caramori Giovanni Faria Silva Fernando Gomes Romeiro | 2014 | World Journal of Gastroenterology2014，20，42： | 6 |
| 2 | Gut-microbiome-brain axis:the crosstalk between the vagus nerve,alpha-synuclein and the brain in Parkinson's disease显示文摘This critical review of the literature shows that there is a close link between the microbiome,the gut,and the brain in Parkinson's disease.The vagus nerve,the main component of the parasympathetic nervous system,is involved in the regulation of immune response,digestion,heart rate,and control of mood.It can detect microbiota metabolites through its afferents,transferring this gut information to the central nervous system.Preclinical and clinical studies have shown the important role played by the gut microbiome and gut-related factors in disease development and progression,as well as treatment responses.These findings suggest that the gut microbiome may be a valuable target for new therapeutic strategies for Parkinson's disease.More studies are needed to better understand the underlying biology and how this axis can be modulated for the patient's benefit. | Júlio César Claudino dos Santos Leandro Freitas Oliveira Felipe Micelli Noleto Camilla Teixeira Pinheiro Gusmão Gerly Anne de Castro Brito Glauce Socorro de Barros Viana | 2023 | Neural Regeneration Research2023，18，12： | 2 |
| 3 | Mold fluxes for continuous casting of steel 显示文摘 | Pinheiro C A Samarasekera I V Brimacombe J K | 1995 | Iron and Steel Maker1995，22，4： | 1 |
| 4 | Prostatic arterial embolization for benign prostatic hyperplasia:short-and intermediate-term results显示文摘 | Pisco J Campos Pinheiro L Bilhim T | 2013 | Radiology2013，266，： | 1 |
| 5 | Photosynthesis underdrought and salt stress:Regulation mechanisms from whole plant to cell 显示文摘 | CHAVES M M FLEXAS J PINHEIRO C | 2009 | Annals of Botany2009，103，： | 1 |
| 6 | Effective Ionization Coefficientsand Electron Drift Velocities in Gas Mixtures of SF6 withHe, Xe, CO2 and N2 from Boltzmann Analysis显示文摘 | Pinheiro M J Loureiro J | 2002 | AppliedPhysics2002，35，23： | 1 |
| 7 | Line Current Harmonics Reduction in Hybrid Multilevel Converters Using Phase-Shifting Transformers 显示文摘 | Rech C Pinheiro J R | 2004 | IEEE Power Electronics Specialists Conference2004，35，1： | 1 |
| 8 | Determination of Formaldehyde by Acetaldehyde in Urine by HPLC显示文摘 | Deandrade J B Deandrade M V Pinheiro H L C | 1999 | American Laboratory1999，31，10： | 1 |
| 9 | Mold flux for continuous casting of steel显示文摘 | Pinheiro C A Samarasekera I V Brimacombe J K | 1996 | Iron and Steelmaker1996，，23： | 1 |
| 10 | EGFR amplification and lack of activating mutations in metaplastic breast carcinomas显示文摘 | Reis-Filho J Pinheiro C Lambros M | 2006 | Pathol2006，209，4： | 1 |
| 11 | Duodenal-jejunal bypass for the treatment of type 2 diabetes in patients with body mass index of 22 ~ 34 kg/m2:a report of 2 cases显示文摘 | COHEN R V SCH1AVON C A PINHEIRO J S | 2007 | Surg Obes Relat Dis2007，3，2： | 1 |
| 12 | Effects of early feed restriction and enzyme supplementation on digestiveenzyme activities in broilers显示文摘 | Pinheiro D F Cruz V C Sartori J R | 2004 | Poultry Science2004，83，： | 1 |
| 13 | Hybrid multilevel converters: unified analysis and design considerations显示文摘 | Rech C Pinheiro J R | 2007 | IEEE Transactions on Industrial Electronics2007，54，2： | 1 |
| 14 | New repetitive control system of PWM inverters with improved dynamic performance under nonperiodic disturbances 显示文摘 | Rech C Pinheiro J R | 2004 | IEEE PESC 042004，，： | 1 |
| 15 | Neuroendoscopic endonasal transseptal approach to the sellar region:study of the first 100 cases显示文摘 | Gondim J Pinheiro I | 2003 | Arq Neuropsiquiatr2003，61，3： | 1 |
| 16 | Malignant mesothelioma mortality in the United States, 1999-2001 显示文摘 | BANG K M PINHEIRO G A WOOD J M | 2006 | Int J Occup Environ Health2006，12，1： | 1 |
| 17 | Effect of humic acid on Cd(Ⅱ),Cu(Ⅱ)and Pb(Ⅱ)uptake by freshwater algae:kinetic and cell wall speciation considerations显示文摘 | Lamelas C Pinheiro J P Slaveykova V I | 2009 | Environmental Science and Technology2009，43，3： | 1 |
| 18 | High prevalence of silicosis among stone carvers in Brazil显示文摘 | ANTAO V C PINHEIRO G A KAVAKAMA J | 2004 | American Journal of Industrial Medicine2004，45，： | 1 |
| 19 | Role of monocarboxylate transporters in human cancers: state of the art显示文摘 | Pinheiro CA Longatto-Filho J Azevedo-Silva | 2012 | J Bioenerg Biomembr2012，44，1： | 1 |
| 20 | Photosynthe-sis under drought and salt stress: regulation mechanisms from whole plant to cell 显示文摘 | CHAVES M M FLEXAS J PINHEIRO C | 2009 | Annals of Botany2009，103，55： | 1 |
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