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| 1 | 青藏高原东南缘芒康地区河流地貌演化的磷灰石U-Th/He记录显示文摘青藏高原东南缘地处印度与欧亚板块碰撞侧向逃逸的特殊构造部位,地势起伏相对较缓,形成三江并流的独特地貌格局。然而,对于东南缘大尺度地形地貌形成机制与水系演化的认识仍存在很大的分歧。本文获得的澜沧江流域芒康地区5个基岩样品磷灰石U-Th/He年龄表明该地区在早一中中新世(23-15Ma)经历了一次区域性冷却事件,且冷却速率在5Ma期间从40℃/Ma降低到28℃/Ma以下。目前可获得的青藏高原东缘一东南缘的低温年代学数据表明:尽管川西一藏东一滇北一带具有相似地貌特征,但高海拔、低起伏地貌面的形成是穿时性的,不能将它作为一个区域上连续的等时面来计算和探讨一个统一的区域抬升启动时间;三江地区地形属于非稳态的过渡型地形,尤其芒康一左贡地区剥蚀速率的差异比较清晰地展示了澜沧江流域地形演化处于非稳态期。此外,河流下切是塑造澜沧江流域的地形地貌主要驱动力之一:干流的侵蚀速率远远高于支流的侵蚀速率;河流下切强烈的地区(如德钦)对应的侵蚀速率及地形起伏度都较大,芒康地区微弱的地形起伏度取决于较低的侵蚀速率。第三纪以来的印度一欧亚板块碰撞导致青藏高原崛起的同时,也对周边尤其藏东南三江地区的地形地貌塑造及气候变化产生重大的影响。 | 肖萍 刘静 王伟 钟宁 曾令森 Raphael Pik 谢克家 | 2015 | 第四纪研究2015，35，2： | 12 |
| 2 | Clinical applications, limitations and future role of transient elastography in the management of liver disease显示文摘Transient elastography(TE) is a reliable tool for the non-invasive assessment of liver fibrosis in routine clinical practice. TE is currently approved for use in Europe, Asia and the United States. The widespread adoption of this technology is certain to increase the use of TE worldwide. Although TE has been well validated in chronic viral hepatitis, its clinical role in other liver diseases remains less clear. The advent of new treatment for chronic hepatitis C and emerging prevalence of non-alcoholic steatohepatitis raises new questions on the role of TE in current clinical practice. This review aims to examine the clinical applications, limitations and future role of TE in current clinical practice in light of the changing epidemiology of liver diseases and new clinical management paradigms. In current clinical practice, TE is the most accurate noninvasive method for diagnosis of liver cirrhosis. TE is useful to rule out fibrosis and cirrhosis but does not have sufficient accuracy to discern between various stages of fibrosis. The clinical role of TE has evolved from cross-sectional point-in-time assessment of fibrosis and cirrhosis to the more relevant role of prediction of vital clinical end-points. This provides clinicians with the ability to modify treatment strategies based on the information provided by TE. TE has evolved over the past decade to become an essential tool to assist the clinician in the management of chronic liver disease. | Pik Eu Chang George Boon-Bee Goh Jing Hieng Ngu Hiang Keat Tan Chee Kiat Tan | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，1： | 5 |
| 3 | 云南德钦白马雪山岩体热历史及其对青藏高原三江地区构造地貌演化的指示意义显示文摘青藏高原三江地区高程缓降、河流及深切峡谷发育,重建其构造-热年代时空演化为把握该地区地形地貌发育演化的内在驱动力提供科学依据。本研究以云南德钦白马雪山岩体为研究对象,开展磷灰石(U-Th)/He及裂变径迹年代学分析,结合已发表的U-Pb和Ar-Ar年代学结果来重塑该地区的构造-热演化历史和地形演化。研究表明,该地区经历了多期快速冷却事件:三叠世的岩浆侵位活动,早白垩世和中-晚始新世的快速冷却,以及中新世和上新世以来的快速剥蚀。青藏高原隆升致使全球气候变化的同时也导致其周缘地区经受强烈侵蚀:中新世以来(21~11Ma)快速冷却速率为10℃/Myr,而上新世以来(ca.5Ma)冷却速率从10℃/Myr增至15℃/Myr。假定区域现今地温梯度为25~35℃/km,河谷剖面不同位置的侵蚀速率及剥蚀量的空间分布特征进一步表明(靠近澜沧江主干道处侵蚀速率远高于其支流,且对应的年龄相对年轻),河流下切及溯源侵蚀的多重效应导致该地区快速剥蚀、剥露,地形起伏加大的瞬态地貌演化规律。 | 肖萍 刘静 王伟 曾令森 谢克家 Raphaёl PIK 钟宁 | 2015 | 岩石学报2015，31，5： | 3 |
| 4 | Ant community succession within eucalypt plantations on used pasture and implications for taxonomic sufficiency in biomonitoring显示文摘 | Schnell M R Pik A J Dangerfield J M | 2003 | Austral Ecology2003，28，： | 1 |
| 5 | Dynamic intraspinous spacer technology for posterior stabilization: case-control study on the safety, sagittal angulation, and pain outcome at 1 -year follow-up evaluation 显示文摘 | Kim K A McDonald M Pik J H | 2007 | Neurosurg Focus2007，22，1： | 1 |
| 6 | Synthesis of the enantiomers ofPk 11195 and comparison of their behaviours as radi- oligands for Pk binding sites in rats显示文摘 | Shah F Hume SP Pik/e VW | 1994 | Nucl Med Biol1994，21，4： | 1 |
| 7 | Clinical accuracy of fluoroscopic computer-assisted pedicle screw fixation:a CT anal- ysis显示文摘 | Rampersaud YR Pik JH Salonen D | 2005 | Spine2005，30，7： | 1 |
| 8 | Microsurgery for small arteriovenous malformations of the brain:results in 110 consecutive patients显示文摘 | Pik JH Morgan MK | 2000 | Neurosurgety2000，47，3： | 1 |
| 9 | Ant community succession within eucalypt plantations on used pasture and implications for taxonomic sufficiency in biomonitoring 显示文摘 | SCHNELL M R PIK A J DANGERFIELD J M | 2003 | Austral Ecology2003，28，： | 1 |
| 10 | Dynamic intraspinous spacer technology for posterior stabilization: case-control study on the safety, sagittal angulation, and pain outcome at 1-year follow-up evaluation显示文摘 | Kim KA McDonald M Pik JH | 2007 | Neurosurg Focus2007，22，1： | 1 |
| 11 | Robo-Erectus: A low-cost autonomous humanoid soccer robot 显示文摘 | Chang Jiu Zhou Pik Kong Yue | 2004 | Advanced Robotics2004，，7： | 1 |
| 12 | The lunar surface as an impact counter显示文摘 | pik E J | 1960 | Monthly Notices of the Royal Astronomical Society1960，120，5： | 1 |
| 13 | Cinacalcet hydrochloride for the treatment of hyperparathyroidism显示文摘 | Verheyen N Pik S Eller K | 2013 | Expert Opin Pharmacother2013，14，6： | 1 |
| 14 | Microsurgery for small arteriovenous malformations of the brain:Results in 110 consecutive patients显示文摘 | Morgan MK | 2000 | Neurosurgery2000，47，： | 1 |
| 15 | 查看详情显示文摘 | (O)pik E J | | 0，，： | 1 |
| 16 | Electrodeposition of CuInSe2 thin films onto Mo-glass substrates显示文摘 | Kois J Bereznev S Mellikov E -pik A | 2006 | Thin Solid Films2006，，： | 1 |
| 17 | 查看详情显示文摘 | Lautner G Kaev J Reut J (O)pik A Rappich J Syritski V Gyurcsányi R E | | 0，，： | 1 |
| 18 | Effect of breathing supplemental oxygen on motion sickness in healthy adults显示文摘 | ZIAVRA N V YEN PIK SANG F D GOLDING J F | 2003 | Mayo Clin Proc2003，78，5： | 1 |
| 19 | Production of curdlan-type polysaccharide by Alcaligenes faecalis in batch and continuous culture显示文摘 | Phillips K R Pik J Lawford H G | 1983 | Canadian Journal of Microbiology1983，29，： | 1 |
| 20 | Enhancement of solubility and dissolution of Coenzyme Q10 using solid dispersion formulation显示文摘 | Nepal PIK Han HK Choi HK | 2010 | IntJ Pharm2010，383，12： | 1 |
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