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172篇 您的检索式:作者名="Phillips M I"
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1Relationship between the exocrine and endocrine pancreas after acute pancreatitis显示文摘AIM:To determine the prevalence and time course of pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.METHODS:Relevant literature cited in three major biomedical journal databases(EMBASE,MEDLINE,and Scopus)was reviewed independently by two authors.There were no language constraints but the search was limited to human studies.Studies included were cohort studies of adult patients who were discharged after an attack of acute pancreatitis.Patients were excluded if they were under 18 years of age or had a previous diagnosis of prediabetes or diabetes mellitus,pancreatic exocrine insufficiency,or chronic pancreatitis.The main outcome measure was the prevalence of concomitant pancreatic exocrine insufficiency in patients who were diagnosed with prediabetes and diabetes mellitus after an attack of acute pancreatitis.Subgroup analysis was conducted for patients who were diagnosed with prediabetes only and those who were diagnosed withdiabetes mellitus only.Subgroup analysis looking at the time course of concomitant pancreatic exocrine and endocrine insufficiency was also conducted.Pooled prevalence and corresponding 95%confidence intervals were calculated for all outcome measures and P-values<0.05 were deemed statistically significant.RESULTS:Eight clinical studies comprising of 234patients met all eligibility criteria.The pooled prevalence of newly diagnosed prediabetes or diabetes in individuals after acute pancreatitis was 43%(95%CI:30%-56%).The pooled prevalence of pancreatic exocrine insufficiency in individuals after acute pancreatitis was 29%(95%CI:19%-39%).The prevalence of concomitant pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes was 40%(95%CI:25%-55%).The prevalence of concomitant pancreatic exocrine insufficiency among individuals with prediabetes alone and diabetes mellitus alone was 41%(95%CI:12%-75%)and 39%(95%CI:28%-51%),respectively.Further analysis showed that the prevalence of concomitant pancreatic exocrine insufficiency in individuals with prediabetes or diabetes decreases over time after an attack of acute pancreatitis.CONCLUSION:Pancreatic exocrine insufficiency occurs in 40%of individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.Further studies are needed to investigate the pathogenesis of diabetes in this setting.Stephanie L M Das James I C Kennedy Rinki Murphy Anthony R J Phillips John A Windsor Maxim S Petrov 2014World Journal of Gastroenterology2014,20,45:9
2CHRNB2 is the second acetylcholine receptor subunit associated with autosomal dominant nocturnal frontal lobe epilepsy 显示文摘Phillips HA Favre I Kirkpatrick M 2001Am J Hum Genet2001,68,1:1
3Big Pharma′s new model in orphan drugs and rare diseases显示文摘PHILLIPS M I 2013Expert Opinion on Orphan Drugs2013,1,1:1
4Influence of the attachment of acidophilic bacteria during the oxidation of mineral sulfides显示文摘 Phillips C V Blake Ⅱ R C 2000Minerals Engineering2000,13,4:1
5Hands as route of transmissions for Klebsiella species显示文摘 Phillips I 1977Br med J1977,2,:1
6Mangroves as filers of shrimp pond effluent:prelictions and biogeochemical research needs显示文摘Robertson A I Phillips M J 1995Hydrobiologia1995,295,:1
7Minireally invasive treatments of osteoporotic vertebral compression fractures:vertebroplasty and kyphoplasty显示文摘PHILLIPS F M PFEIFER B A LIEBERMAN I H 2003Instr Course Leet2003,52,3:1
8Enhancement of monocyte adhesion to endothelial cells by oxidatively modifide low density lipoprotein in mediated by activation of CD11b显示文摘WeberC Kajiyama S Phillips M I 1995Biolchem Biophys Res Comm1995,206,:1
9CHRNB2 is the second acetylcholine receptor subunit associated with autosomal dominant nocturnal frontal lobe epilepsy显示文摘Phillips HA Favre I Kirkpatrick M 2001Am J Hum Genet2001,68,1:1
10LOX-1 and angiotensin receptors, and their interplay显示文摘Wang X Phillips M I Mehta J L 2011Cardiovasc Drugs Ther2011,25,5:1
11Removal of dis- solved nitrogen, phosphorus and carbon from stormwater by biofihration mesocosms 显示文摘Henderson C Greenway M Phillips I 2007Water Sci Technol2007,55,4:1
12Antisense oligonucleotides: new tools for physiology显示文摘 Gyurko R 1997News Physiol Sci1997,12,:1
13Impacts of greenwaste biochar on ammonia volatilisation from bauxite processing residue sand显示文摘Chen C R Phillips I R Condron L M 2013Plant and Soil2013,367,12:1
14Impacts of greenwaste biochar on ammonia volatilization from bauxite processing residue sand显示文摘Chen C R Phillips I R Condron L M 2013P/ant and Soil2013,367,12:1
15Loss of chromosomal region 10Q23-25 in prostate cancer显示文摘Gray I C Phillips S M Lee S J 1995Cancer Ras1995,55,:1
16An in vivo comparison of the potential for extravertebral cement leak after vertebroplasty and kyphoplasty显示文摘Phillips F M Todd-Wetzel F Lieberman I 2002Spine2002,27,19:1
17Mangroves as filers of shrimp pond effluent: predictions and biogeochemical research needs显示文摘Robertson A I Phillips M J 1995Hydrobiologia1995,295,:1
18Mechanism of shrinkage control in polyester resins containing lowprofile additives 显示文摘Bucknall C B Partridge I K Phillips M J 1991Polymer1991,32,4:1
19Stability of net- worked control systems显示文摘I Zhang Wei Branicky M S Phillips S M 2001IEEE Control Systems2001,21,1:1
20Does the use of antibiotics in food animals pose a risk to human health? A critical review of published data 显示文摘Phillips I Casewell M Cox T 2004J Antimicrob Chemoth2004,53,:1
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