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| 1 | Mayombian ethnic,vegetables low intake,insulin treatment,diabetic nephropathy and severe diabetic retinopathy are determinants of blindness in diabetic Africans显示文摘AIM:to determine the frequency and causes of blindness in diabetic Africans.METHODS:The study was a cross-sectional survey carried out among known black diabetics consecutively admitted at the Teaching Hospital,University of Kinshasa,between 2005 and 2007.Examination methods included interviewer-administered structured question naire,eye examinations(visual acuity,tonometry,funduscopy),and fasting plasma glycaemia test.RESULTS:Of the 227 patients examined,15.9% had blindness.Univariate analyses showed significant association between female,severity of diabetic retinopathy,Mayombian ethnic group,use of insulin treatment,low intake of vegetables,diabetic nephropathy,open angle glaucoma and blindness in all diabetics.After logistic regression,only diabetic nephropathy,use of insulin treatment,macular oedema,Mayombian ethnic group and vegetables low intake were the independent risk factors of blindness in all diabetics.However,after logistic regression in the sub-group with diabetic retinopathy,only open angle glaucoma and proliferative diabetic retinopathy were the independent determinants of blindness.CONCLUSION:The majority of the causes of blindness in these diabetic Africans are avoidable.It is recommended that appropriate diabetes care,nutrition education,periodic eye examination and laser photocoagulation facilities should be provided for treating diabetics in sub-Saharan Africa. | Mvitu Muaka Moise Longo-Mbenza Benjamin Cibanda Yokobo Enoch Longo Phemba Igor | 2013 | International Journal of Ophthalmology(English edition)2013，6，5： | 6 |
| 2 | Retinopathy in non diabetics, diabetic retinopathy and oxidative stress: a new phenotype in Central Africa?显示文摘AIM:To evaluate the rates of retinopathy without diabetes and diabetic retinopathy(DR),associated with some markers of oxidative stress,antioxidants and cardiometabolic risk factors.METHODS:We determined the prevalence of DR in 150type 2 diabetes mellitus(T2DM)patients,that of retinopathy in 50 non diabetics,the levels of body mass index(BMI),waist circumference(WC),blood pressure,lipids,8-isoprostane,8-hydroxydeoxyguanosine(8-oHdG),gamma-glutamyl transferase(GGT),oxidized low density lipoprotein(LDL)(OxLDL),thiobarbituric acid reacting substances(TBARS),reduced glutathione(GSH),superoxide dismutase(SOD),uric acid,creatinine,albumin,total antioxidant status(TAOS),zinc,selenium,magnesium,vitamin C,vitamin D,vitamin E,glucose,apolipoprotein B(ApoB).RESULTS:The prevalences of DR at 53y and Rtp at62y were 44%(n=66)and 10%(n=5),respectively.Thehighest levels of 8-isoprostane,8-OHdG,TBARS,SOD,and OxLDL were in DR.The lowest levels of vitamin D,vitamin C,TAOS,and vitamin E were in DR.In the casecontrol study discriminant analysis,the levels of vitamin C,vitamin D,ApoB,8-OHdG,creatinine,Zn,vitamin E,and WC distinguished significantly non-diabetics without DR(controls),T2DM patients without DR and T2DM patients with DR.CONCLUSION:Anticipation of DR onset is significantly associated with the exageration of oxidative stress biomarkers or decrease of antioxidants in African type 2diabetics.Prevention of oxidative stress and abdominal obesity is needed.Supplementation in vitamin C,D,and E should be recommended as complement therapies of T2DM. | Benjamin Longo-Mbenza Moise Mvitu Muaka Wayiza Masamba Lucien Muizila Kini Igor Longo Phemba Dalida Kibokela Ndembe Doris Tulomba Mona | 2014 | International Journal of Ophthalmology(English edition)2014，7，2： | 4 |
| 3 | Prophylactic Use of Transjugular Intrahepatic Portosystemic Shunt Aids in the Treatment of Refractory Ascites: Metaregression and Trial Sequential Meta-analysis显示文摘 | Ren Pin Chen Xiao Ju Zhu Ge Zhi Ming Huang Xiao Hua Ye Chang Yuan Hu Guang Rong Lu De Yi Lu Igor Longe Phemba | 2014 | Journal of Clinical Gastroenterology2014，，3： | 2 |
| 4 | Mayombian 种族,蔬菜低吸入,胰岛素处理,糖尿病的 nephropathy 和严重糖尿病的 retinopathy 是在糖尿病的非洲人的盲目的决定因素显示文摘AIM:to determine the frequency and causes of blindness in diabetic Africans.METHODS:The study was a cross-sectional survey carried out among known black diabetics consecutively admitted at the Teaching Hospital,University of Kinshasa,between 2005 and 2007.Examination methods included interviewer-administered structured question naire,eye examinations(visual acuity,tonometry,funduscopy),and fasting plasma glycaemia test.RESULTS:Of the 227 patients examined,15.9% had blindness.Univariate analyses showed significant association between female,severity of diabetic retinopathy,Mayombian ethnic group,use of insulin treatment,low intake of vegetables,diabetic nephropathy,open angle glaucoma and blindness in all diabetics.After logistic regression,only diabetic nephropathy,use of insulin treatment,macular oedema,Mayombian ethnic group and vegetables low intake were the independent risk factors of blindness in all diabetics.However,after logistic regression in the sub-group with diabetic retinopathy,only open angle glaucoma and proliferative diabetic retinopathy were the independent determinants of blindness.CONCLUSION:The majority of the causes of blindness in these diabetic Africans are avoidable.It is recommended that appropriate diabetes care,nutrition education,periodic eye examination and laser photocoagulation facilities should be provided for treating diabetics in sub-Saharan Africa. | Mvitu Muaka Moise Longo-Mbenza Benjamin Cibanda Yokobo Enoch Longo Phemba Igor | 2013 | International Journal of Ophthalmology(English edition)2013，6，5： | 0 |
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